Curcumin-primed exosomes potently ameliorate cognitive function in AD mice by inhibiting hyperphosphorylation of the Tau protein through the AKT/GSK-3β pathway

Nanoscale - Tập 11 Số 15 - Trang 7481-7496
Hao Wang1,2,3,4, Hai-juan Sui5,6,2,3, Yan Zheng1,2,3,4, Yibin Jiang1,2,3,4, Yijie Shi1,2,3,4, Jia Liang6,2,7,3, Liang Zhao1,2,3,4
1Jinzhou 121000
2Jinzhou Medical University
3P. R. China
4School of Pharmacy, Jinzhou Medical University, Jinzhou 121000, P. R. China
5Department of Pharmacology, Jinzhou Medical University, Jinzhou, P R China
6Jinzhou
7Life Science Institution, Jinzhou Medical University, Jinzhou, P R China

Tóm tắt

Curcumin-primed exosomes (Exo-Cur) can better relieve the symptoms of AD by inhibiting phosphorylation of Tau protein through AKT/GSK-3β pathway.

Từ khóa


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