Crystal structure of the breakage–reunion domain of DNA gyrase

Nature - Tập 388 Số 6645 - Trang 903-906 - 1997
João H. Morais‐Cabral1, Andrew P. Jackson1, Clare V. Smith1, Nita SHIKOTRA1, Anthony Maxwell1, Robert Liddington1
1Department of Biochemistry, University of Leicester, LE1 7RH, Leicester, UK

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Tài liệu tham khảo

Reece, R. J. & Maxwell, A. DNA gyrase: structure and function. CRC Crit. Rev. Biochem. Mol. Biol. 26, 335–375 (1991).

Wigley, D. B. in Nucleic Acids and Molecular Biology(eds Eckstein, F. &Lilley, D. M. J.) 165–176 (Springer, Berlin and Heidelberg, (1995)).

Berger, J. M., Gamblin, S. J., Harrison, S. C. & Wang, J. C. Structure at 2.7 Å resolution of a 92K yeast DNA topoisomerase II fragment. Nature 379, 225–232 (1996).

Reece, R. J. & Maxwell, A. Probing the limits of the DNA breakage–reunion domain of the Escherichia coli DNA gyrase A protein. J. Biol. Chem. 266, 3540–3546 (1991).

Kampranis, S. C. & Maxwell, A. Conversion of DNA gyrase into a conventional type II topoisomerase. Proc. Natl Acad. Sci. USA 93, 14416–14421 (1996).

Caron, P. R. & Wang, J. C. Appendix II: Alignment of primary sequences of DNA topoisomerases. Adv. Pharmacol. 29B, 271–297 (1994).

Kirchhausen, T., Wang, J. C. & Harrison, S. C. DNA gyrase and its complexes with DNA: direct observation by electron microscopy. Cell 41, 933–943 (1985).

Krueger, S.et al. Neutron and light-scattering studies of DNA gyrase and its complex with DNA. J. Mol. Biol. 211, 211–220 (1990).

Schultz, S. C., Shields, G. C. & Steitz, T. A. Crystal structure of a CAP–DNA complex: the DNA is bent by 90°. Science 253, 1001–1007 (1991).

Somers, W. S. & Phillips, S. E. V. Crystal structure of the met repressor–operator complex at 2.8 Å resolution reveals recognition by β-strands. Nature 359, 387–393 (1992).

Willmott, C. J. R. & Maxwell, A. Asingle point mutation in the DNA gyrase A protein greatly reduces the binding of fluoroquinolones to the gyrase-DNA complex. Antimicrob. Agents Chemother. 37, 126–127 (1993).

Roca, J. & Wang, J. C. DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism. Cell 77, 609–616 (1994).

Roca, J., Berger, J. M., Harrison, S. C. & Wang, J. C. DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. Proc. Natl Acad. Sci. USA 93, 4057–4062 (1996).

Otwinowski, Z. in Data Collection and Processing(eds Sawyer, L., Isaacs, N. &Bailey, S.) 56–62 (SERC, Warrington, UK, (1993)).

Collaborative Computational Project, N. 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760–763 (1994).

Jones, T. A. Interactive computer-graphics—FRODO. Meth. Enzymol. 115, 157–171 (1985).

Brünger, A. T. X-PLOR Version 3.1, a System for Crystallography and NMR.(New Haven, Connecticut, (1992)).

Kraulis, P. J. Molscript—a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallog. 24, 946–950 (1991).

Merrit, E. A. & Murphy, M. E. P. Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr. D 50, 869–873 (1994).

Bacon, D. J. & Anderson, W. F. Afast algorithm for rendering space-filling molecule pictures. J. Mol. Graph. 6, 219–220 (1988).

Lindsley, J. E. & Wang, J. C. On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II. J. Biol. Chem. 268, 8096–8104 (1993).

Nicholls, A. GRASP: Graphical representation and analysis of surface properties.(Columbia University, New York, (1992)).