Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation

Laboratory Investigation - Tập 101 - Trang 733-744 - 2021
Diego A. Pedroza1, Ramadevi Subramani1,2, Kira Tiula2, Anthony Do2, Navya Rashiraj2, Adriana Galvez2, Animesh Chatterjee2, Alejandra Bencomo2, Servando Rivera2, Rajkumar Lakshmanaswamy1,2
1Graduate School of Biomedical Sciences, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA
2Center of Emphasis in Cancer, Department of Molecular and Translational Medicine, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA

Tài liệu tham khảo

Siegel, 2020, Cancer statistics, 2020, CA Cancer J Clin, 70, 7, 10.3322/caac.21590 Shehu, 2011, The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells, Mol Endocrinol, 25, 754, 10.1210/me.2010-0261 Kabos, 2012, Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures, Breast Cancer Res Treat, 135, 415, 10.1007/s10549-012-2164-8 Nilsson, 2001, Mechanisms of estrogen action, Physiol Rev, 81, 1535, 10.1152/physrev.2001.81.4.1535 Yager, 2006, Estrogen carcinogenesis in breast cancer, N Engl J Med, 354, 270, 10.1056/NEJMra050776 Liang, 2018, Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609), J Hematol Oncol, 11, 124, 10.1186/s13045-018-0670-9 Howlader, 2014, US incidence of breast cancer subtypes defined by joint hormone receptor and HER2 status, J Natl Cancer Inst, 106, dju055, 10.1093/jnci/dju055 Craven, 2008, PGRMC1: a new biomarker for the estrogen receptor in breast cancer, Breast Cancer Res, 10, 10.1186/bcr2191 Ferreira Almeida, 2020, Estrogen receptor-positive (ER+) breast cancer treatment: are multi-target compounds the next promising approach?, Biochem Pharmacol, 117 AlFakeeh, 2018, Overcoming endocrine resistance in hormone receptor-positive breast cancer, Curr Oncol, 25, S18, 10.3747/co.25.3752 Mueck, 2014, Genomic and non-genomic actions of progestogens in the breast, J Steroid Biochem Mol Biol, 142, 62, 10.1016/j.jsbmb.2013.08.011 Wang, 2014, G protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids, Int J Mol Sci, 15, 15412, 10.3390/ijms150915412 Cenciarini, 2019, Molecular mechanisms underlying progesterone receptor action in breast cancer: Insights into cell proliferation and stem cell regulation, Steroids, 152, 108503, 10.1016/j.steroids.2019.108503 Wilkenfeld, 2018, Communication between genomic and non-genomic signaling events coordinate steroid hormone actions, Steroids, 133, 2, 10.1016/j.steroids.2017.11.005 Liu, 2013, Estrogen-induced nongenomic calcium signaling inhibits lipopolysaccharide-stimulated tumor necrosis factor α production in macrophages, PLoS ONE, 8, e83072, 10.1371/journal.pone.0083072 Pang, 2013, Characterization, neurosteroid binding and brain distribution of human membrane progesterone receptors δ and {epsilon} (mPRδ and mPR{epsilon}) and mPRδ involvement in neurosteroid inhibition of apoptosis, Endocrinology, 154, 283, 10.1210/en.2012-1772 Mir, 2012, Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients, Int J Cancer, 131, E1, 10.1002/ijc.26432 Peluso, 2008, Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1, J Clin Endocrinol Metab, 93, 1592, 10.1210/jc.2007-2771 Crudden, 2005, Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors, Tumour Biol, 26, 142, 10.1159/000086485 Ruan, 2017, Increased expression of progesterone receptor membrane component 1 is associated with aggressive phenotype and poor prognosis in ER-positive and negative breast cancer, Menopause, 24, 203, 10.1097/GME.0000000000000739 Ji, 2012, [Expression of progesterone receptor membrane component-1 is associated with the malignant phenotypes of breast cancer], Nan Fang Yi Ke Da Xue Xue Bao, 32, 635 Pedroza, 2020, Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling, Br J Cancer, 123, 1326, 10.1038/s41416-020-0992-6 Ruan, 2012, Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells, Gynecol Endocrinol, 28, 863, 10.3109/09513590.2012.671396 Zhou, 2013, Medroxyprogesterone acetate-driven increase in breast cancer risk might be mediated via cross-talk with growth factors in the presence of progesterone receptor membrane component-1, Maturitas, 76, 129, 10.1016/j.maturitas.2013.06.013 Ruan, 2012, Progestogens and membrane-initiated effects on the proliferation of human breast cancer cells, Climacteric, 15, 467, 10.3109/13697137.2011.648232 Schneck, 2013, Membrane-receptor initiated proliferative effects of dienogest in human breast cancer cells, Gynecol Endocrinol, 29, 160, 10.3109/09513590.2012.730572 Neubauer, 2013, Overexpression of progesterone receptor membrane component 1: possible mechanism for increased breast cancer risk with norethisterone in hormone therapy, Menopause, 20, 504, 10.1097/gme.0b013e3182755c97 Willibald, 2017, Progesterone receptor membrane component 1 is phosphorylated upon progestin treatment in breast cancer cells, Oncotarget, 8, 72480, 10.18632/oncotarget.19819 Li, 2019, PGRMC1 can trigger estrogen-dependent proliferation of breast cancer cells: estradiol vs. equilin vs. ethinylestradiol, Climacteric, 22, 483, 10.1080/13697137.2019.1582624 Ciriello, 2015, Comprehensive molecular portraits of invasive lobular breast cancer, Cell, 163, 506, 10.1016/j.cell.2015.09.033 Mote, 2002, Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis, Breast Cancer Res Treat, 72, 163, 10.1023/A:1014820500738 Mote PA, Graham JD, Clarke CL. Progesterone receptor isoforms in normal and malignant breast. Ernst Schering Found Symp Proc. 2007:77–107. McGowan, 2004, Effect of progesterone receptor a predominance on breast cancer cell migration into bone marrow fibroblasts, Breast Cancer Res Treat, 83, 211, 10.1023/B:BREA.0000014041.58977.80 Khan, 2012, Differential regulation of breast cancer-associated genes by progesterone receptor isoforms PRA and PRB in a new bi-inducible breast cancer cell line, PLoS ONE, 7, e45993, 10.1371/journal.pone.0045993 Kariagina, 2008, Progesterone receptor isoform functions in normal breast development and breast cancer, Crit Rev Eukaryot Gene Expr, 18, 11, 10.1615/CritRevEukarGeneExpr.v18.i1.20 Ahmed, 2010, Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity, J Biol Chem, 285, 24775, 10.1074/jbc.M110.134585 Meyer, 1990, Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor, EMBO J, 9, 3923, 10.1002/j.1460-2075.1990.tb07613.x Neubauer, 2008, Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1, Breast Cancer Res, 10, 10.1186/bcr2155 Mifsud, 2002, Membrane-bound progesterone receptors contain a cytochrome b5-like ligand-binding domain, Genome Biol, 3, 10.1186/gb-2002-3-12-research0068 Min, 2005, Molecular identification of adrenal inner zone antigen as a heme-binding protein, FEBS J, 272, 5832, 10.1111/j.1742-4658.2005.04977.x Hughes, 2007, Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes, Cell Metab, 5, 143, 10.1016/j.cmet.2006.12.009 Selmin, 1996, Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, Carcinogenesis, 17, 2609, 10.1093/carcin/17.12.2609 Cahill, 2007, Progesterone receptor membrane component 1: an integrative review, J Steroid Biochem Mol Biol, 105, 16, 10.1016/j.jsbmb.2007.02.002 Osborne, 1998, Tamoxifen in the treatment of breast cancer, N Engl J Med, 339, 1609, 10.1056/NEJM199811263392207 Early Breast Cancer Trialists' Collaborative Group (EBCTCG)., 2005, Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials, Lancet, 365, 1687, 10.1016/S0140-6736(05)66544-0 Fan, 2015, Endocrine therapy resistance in breast cancer: current status, possible mechanisms and overcoming strategies, Future Med Chem, 7, 1511, 10.4155/fmc.15.93 Bardou, 2003, Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases, J Clin Oncol, 21, 1973, 10.1200/JCO.2003.09.099 Mohammed, 2015, Progesterone receptor modulates ERα action in breast cancer, Nature, 523, 313, 10.1038/nature14583 Shah, 2003, Hormone replacement therapy containing progestins and given continuously increases breast carcinoma risk in Sweden, Cancer, 98, 1552, 10.1002/cncr.11697 Busund, 2018, Progestin-only and combined oral contraceptives and receptor-defined premenopausal breast cancer risk: the Norwegian Women and Cancer Study, Int J Cancer, 142, 2293, 10.1002/ijc.31266 Nachtigall, 2018, Contemporary hormonal contraception and the risk of breast cancer, N Engl J Med, 378, 1265 Blank, 2008, Both ovarian hormones estrogen and progesterone are necessary for hormonal mammary carcinogenesis in ovariectomized ACI rats, Proc Natl Acad Sci USA, 105, 3527, 10.1073/pnas.0710535105 Chlebowski, 2015, Breast cancer after use of estrogen plus progestin and estrogen alone: analyses of data from 2 women's health initiative randomized clinical trials, JAMA Oncol, 1, 296, 10.1001/jamaoncol.2015.0494 Boopalan, 2015, Receptor activator for nuclear factor-κB ligand signaling promotes progesterone-mediated estrogen-induced mammary carcinogenesis, Cancer Sci, 106, 25, 10.1111/cas.12571 Schwartz, 2016, Rapid steroid hormone actions via membrane receptors, Biochim Biophys Acta, 1863, 2289, 10.1016/j.bbamcr.2016.06.004 Christ, 1995, Rapid aldosterone signaling in vascular smooth muscle cells: involvement of phospholipase C, diacylglycerol and protein kinase C alpha, Biochem Biophys Res Commun, 213, 123, 10.1006/bbrc.1995.2106 Kousteni, 2001, Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity, Cell, 104, 719 Kaluka, 2015, Spectroscopic and mutagenesis studies of human PGRMC1, Biochemistry, 54, 1638, 10.1021/bi501177e Asperger, 2020, Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression, Breast Cancer Res, 22, 10.1186/s13058-020-01312-8 Carneiro, 1993, Age-related changes in melatonin modulation of sympathetic neurotransmission, J Pharmacol Exp Ther, 266, 1536 Ahmed, 2012, S2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling, Expert Opin Drug Metab Toxicol, 8, 361, 10.1517/17425255.2012.658367 Payne, 2004, Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones, Endocr Rev, 25, 947, 10.1210/er.2003-0030