Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers

Akiyoshi Morinaga1,2, Kazuhiro Hasegawa1, Ryo Nomura1, Tadakazu Ookoshi1, Daisaku Ozawa1, Yuji Goto3, Masahito Yamada4, Hironobu Naiki1
1Division of Molecular Pathology, Department of Pathological Sciences, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan
2Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan
3Institute for Protein Research, Osaka University, Osaka 565-0871, Japan
4Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa 920‐8640, Japan

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