Critical issues in hematology: anemia, thrombocytopenia, coagulopathy, and blood product transfusions in critically ill patients

Clinics in Chest Medicine - Tập 24 Số 4 - Trang 607-622 - 2003
Reed E. Drews1,2
1Department of Medicine, Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
2Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02115, USA

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Vincent, 2002, Anemia and blood transfusion in critically ill patients, JAMA, 288, 1499, 10.1001/jama.288.12.1499

Stéphan, 1999, Thrombocytopenia in a surgical ICU, Chest, 115, 1363, 10.1378/chest.115.5.1363

Chakraverty, 1996, The incidence and cause of coagulopathies in an intensive care population, Br J Haematol, 93, 460, 10.1046/j.1365-2141.1996.5101050.x

Goodnough, 2001, Anemia, transfusion, and mortality, N Engl J Med, 345, 1272, 10.1056/NEJM200110253451711

Hébert, 2002, Red blood cell transfusions in critically ill patients, JAMA, 288, 1525, 10.1001/jama.288.12.1525

Kruskall, 1997, The perils of platelet transfusions, N Engl J Med, 337, 1914, 10.1056/NEJM199712253372609

Drews, 2000, Thrombocytopenic disorders in critically ill patients, Am J Respir Crit Care Med, 162, 347, 10.1164/ajrccm.162.2.ncc3-00

1998, Guideline for the use of fresh-frozen plasma, S Afr Med J, 88, 1344

Pindur, 1999, The use of prothrombin complex concentrates in the treatment of hemorrhages induced by oral anticoagulation, Thromb Res, 95, S57, 10.1016/S0049-3848(99)00085-7

Hedner, 2002, Potential role for rFVIIa in transfusion medicine, Transfusion, 42, 114, 10.1046/j.1537-2995.2002.00017.x

Means, 1992, Progress in understanding the pathogenesis of the anemia of chronic disease, Blood, 80, 1639, 10.1182/blood.V80.7.1639.1639

Guyatt, 1990, Diagnosis of iron-deficiency anemia in the elderly, Am J Med, 88, 205, 10.1016/0002-9343(90)90143-2

Cook, 1982, Clinical evaluation of iron deficiency, Semin Hematol, 19, 6

van den Broek, 1998, Iron status in pregnant women: which measurements are valid?, Br J Haematol, 103, 817, 10.1046/j.1365-2141.1998.01035.x

Jones, 1998, Serum creatinine levels in the US population: third national health and nutrition examination survey, Am J Kidney Dis, 32, 992, 10.1016/S0272-6386(98)70074-5

Marchand, 1980, The predictive value of serum haptoglobin in hemolytic disease, JAMA, 243, 1909, 10.1001/jama.243.19.1909

George, 1998, Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: diagnosis and management, J Clin Apheresis, 13, 120, 10.1002/(SICI)1098-1101(1998)13:3<120::AID-JCA5>3.0.CO;2-E

Vanderschueren, 2000, Thrombocytopenia and prognosis in intensive care, Crit Care Med, 28, 1871, 10.1097/00003246-200006000-00031

Leslie, 1991, Laboratory hemostatic abnormalities in massively transfused patients given red blood cells and crystalloid, Am J Clin Pathol, 96, 770, 10.1093/ajcp/96.6.770

McKrae, 1996, Posttransfusion purpura: two unusual cases and a literature review, Am J Hematol, 52, 205, 10.1002/(SICI)1096-8652(199607)52:3<205::AID-AJH13>3.0.CO;2-E

Peck-Radosavljevic, 2000, Thrombopoietin induces rapid resolution of thrombocytopenia after orthotopic liver transplantation through increased platelet production, Blood, 95, 795, 10.1182/blood.V95.3.795.003k25_795_801

George, 1998, Drug-induced thrombocytopenia: a systematic review of published reports, Ann Intern Med, 129, 886, 10.7326/0003-4819-129-11_Part_1-199812010-00009

Wade, 2002, H2 antagonist-induced thrombocytopenia: is this a real phenomenon?, Intensive Care Med, 28, 459, 10.1007/s00134-002-1233-6

George, 1996, Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods of the American Society of Hematology, Blood, 88, 3, 10.1182/blood.V88.1.3.3

Warkentin, 1999, Heparin-induced thrombocytopenia: a ten-year retrospective, Annu Rev Med, 50, 129, 10.1146/annurev.med.50.1.129

Eichler, 1999, First workshop for detection of heparin-induced antibodies: validation of the heparin-induced platelet-activation test (HIPA) in comparison with PF4/heparin ELISA, Thromb Haemost, 81, 625, 10.1055/s-0037-1614536

Levine, 2002, The antiphospholipid syndrome, N Engl J Med, 346, 752, 10.1056/NEJMra002974

Galli, 2003, Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature, Blood, 101, 1827, 10.1182/blood-2002-02-0441

Greenberg, 1987, Measurement of plasma fibrin D-dimer levels with the use of a monoclonal antibody coupled to latex beads, Am J Clin Pathol, 87, 94, 10.1093/ajcp/87.1.94

Ginsberg, 1998, Sensitivity and specificity of a whole blood assay for D-dimer in the diagnosis of pulmonary embolism, Ann Intern Med, 129, 1006, 10.7326/0003-4819-129-12-199812150-00003

1988, Consensus conference. Perioperative red blood cell transfusion, JAMA, 260, 2700, 10.1001/jama.260.18.2700

1992, Practice strategies for elective red blood cell transfusion, Ann Intern Med, 116, 403, 10.7326/0003-4819-116-5-403

1996, Practice guidelines for blood component therapy: a report by the American Society of Anesthesiologists Task Force on Blood Component Therapy, Anesthesiology, 84, 732, 10.1097/00000542-199603000-00032

1997, Guidelines for red blood cell and plasma transfusions of adults and children, Can Med Assoc J, 156, S1

Hébert, 1995, Transfusion requirements in critical care: a pilot study, JAMA, 273, 1439, 10.1001/jama.273.18.1439

Hébert, 1999, A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care, N Engl J Med, 340, 409, 10.1056/NEJM199902113400601

Carson, 1996, Effect of anaemia and cardiovascular disease on surgical mortality and morbidity, Lancet, 348, 1055, 10.1016/S0140-6736(96)04330-9

Hébert, 1997, Does transfusion practice affect mortality in critically ill patients?, Am J Respir Crit Care Med, 155, 1618, 10.1164/ajrccm.155.5.9154866

Hébert, 2001, Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?, Crit Care Med, 29, 227, 10.1097/00003246-200102000-00001

Wu, 2001, Blood transfusion in elderly patients with acute myocardial infarction, N Engl J Med, 345, 1230, 10.1056/NEJMoa010615

Bracey, 1999, Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome, Transfusion, 39, 1070, 10.1046/j.1537-2995.1999.39101070.x

von Ahsen, 1999, Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients, Crit Care Med, 27, 2630, 10.1097/00003246-199912000-00005

Heddle, 1993, A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions, Transfusion, 33, 794, 10.1046/j.1537-2995.1993.331094054613.x

Dodd, 2002, Current prevalence and incidence of infectious disease markers and estimated window-period risk in the American Red Cross blood donor population, Transfusion, 42, 975, 10.1046/j.1537-2995.2002.00174.x

Marik, 1993, Effect of stored-blood transfusion on oxygen delivery in patients with sepsis, JAMA, 269, 3024, 10.1001/jama.269.23.3024

van de Watering, 1998, Beneficial effects of leukocyte depletion of transfused blood on postoperative complications in patients undergoing cardiac surgery: a randomized clinical trial, Circulation, 97, 562, 10.1161/01.CIR.97.6.562

Corwin, 1999, Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized double-blind placebo-controlled trial, Crit Care Med, 27, 2346, 10.1097/00003246-199911000-00004

Corwin, 2002, Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial, JAMA, 288, 2827, 10.1001/jama.288.22.2827

Carson, 2002, Should patients in intensive care units receive erythropoietin?, JAMA, 288, 2884, 10.1001/jama.288.22.2884

Contreras, 1998, Final statement from the consensus conference on platelet transfusion, Transfusion, 38, 796, 10.1046/j.1537-2995.1998.38898375520.x

Klumpp, 1999, Clinical consequences of alterations in platelet transfusion dose: a prospective, randomized, double-blind trial, Transfusion, 39, 674, 10.1046/j.1537-2995.1999.39070674.x

1985, Consensus conference. Fresh-frozen plasma: indications and risks, JAMA, 253, 551, 10.1001/jama.253.4.551

Hirsh, 1998, Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range, Chest, 114, 445S, 10.1378/chest.114.5_Supplement.445S

Lisman, 2003, Recombinant factor VIIa enhances deposition of platelets with congenital or acquired αIIbβ3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor-independent thrombin generation, Blood, 101, 1864, 10.1182/blood-2002-09-2761

Hoffman, 2001, The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis, Semin Hematol, 38, 6, 10.1016/S0037-1963(01)90140-4

Deveras, 2002, Reversal of warfarin-induced excessive anticoagulation with recombinant human factor VIIa concentrate, Ann Intern Med, 137, 884, 10.7326/0003-4819-137-11-200212030-00009

Yan, 2001, Low levels of protein C are associated with poor outcome in severe sepsis, Chest, 120, 915, 10.1378/chest.120.3.915

Bernard, 2001, Efficacy and safety of recombinant human activated protein C for severe sepsis, N Engl J Med, 344, 699, 10.1056/NEJM200103083441001

Ely, 2003, Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis, Crit Care Med, 31, 12, 10.1097/00003246-200301000-00002

Warren, 2002, Risks and benefits of activated protein C treatment for severe sepsis, N Engl J Med, 347, 1027, 10.1056/NEJMsb020574

Siegel, 2002, Assessing the use of activated protein C in the treatment of severe sepsis, N Engl J Med, 347, 1030, 10.1056/NEJMsb021512

Rintala, 1998, Protein C in the treatment of coagulopathy in meningococcal disease, Crit Care Med, 26, 965, 10.1097/00003246-199805000-00038