CpG Oligodeoxynucleotides Prevent the Development of Scleroderma-Like Syndrome in Tight-Skin Mice by Stimulating a Th1 Immune Response
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Bocchieri, 1991, Evidence for autoimmunity in the tight skin mouse model of systemic sclerosis, Arthritis Rheum, 34, 599, 10.1002/art.1780340512
Bona, 1994, Autoantibodies in scleroderma and tightskin mice, Curr Opin Immunol, 6, 931, 10.1016/0952-7915(94)90016-7
Chu, 1997, CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity, J Exp Med, 186, 1623, 10.1084/jem.186.10.1623
Dodig, 2001, Development of the tight-skin phenotype in immune-deficient mice, Arthritis Rheum, 44, 723, 10.1002/1529-0131(200103)44:3<723::AID-ANR122>3.0.CO;2-V
Grassegger, 1998, Interferon-gamma in the treatment of systemic sclerosis: A randomized controlled multicentre trial, Br J Dermatol, 139, 639, 10.1046/j.1365-2133.1998.02460.x
Green, 1976, Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton, Am J Pathol, 82, 493
Hasegawa, 1997, Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis, J Rheumatol, 24, 328
Hatakeyama, 1996, Correlation between the concentration of serum anti-topoisomerase I autoantibodies and histological and biochemical alterations in the skin of tight skin mice, Cell Immunol, 167, 135, 10.1006/cimm.1996.0017
Hu, 2003, Correlation of serum anti-DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis, Arthritis Rheum, 48, 1363, 10.1002/art.10977
Jakob, 1998, Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA, J Immunol, 161, 3042
Kline, 1998, Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma, J Immunol, 160, 2555
Klinman, 1999, Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection, Infect Immun, 67, 5658, 10.1128/IAI.67.11.5658-5663.1999
Klinman, 1999, Immune recognition of foreign DNA: A cure for bioterrorism?, Immunity, 11, 123, 10.1016/S1074-7613(00)80087-4
Kodera, 2002, Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts, Proc Natl Acad Sci USA, 99, 3800, 10.1073/pnas.052709999
Krieg, 2002, CpG motifs in bacterial DNA and their immune effects, Annu Rev Immunol, 20, 709, 10.1146/annurev.immunol.20.100301.064842
Krieg, 1995, CpG motifs in bacterial DNA trigger direct B-cell activation, Nature, 374, 546, 10.1038/374546a0
McGaha, 2001, Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes, J Invest Dermatol, 116, 136, 10.1046/j.1523-1747.2001.00217.x
McGaha, 2003, Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts, Arthritis Rheum, 48, 2275, 10.1002/art.11089
Mor, 1997, Do DNA vaccines induce autoimmune disease?, Hum Gene Ther, 8, 293, 10.1089/hum.1997.8.3-293
Needleman, 1992, Immunologic aspects of scleroderma, Curr Opin Rheumatol, 4, 862
Ong, 1998, Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma, Eur J Immunol, 28, 2619, 10.1002/(SICI)1521-4141(199809)28:09<2619::AID-IMMU2619>3.0.CO;2-M
Ong, 1999, A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice, Cell Immunol, 196, 60, 10.1006/cimm.1999.1537
Postlethwaite, 1995, Role of T cells and cytokines in effecting fibrosis, Int Rev Immunol, 12, 247, 10.3109/08830189509056716
Saito, 2002, CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse, J Clin Invest, 109, 1453, 10.1172/JCI0215078
Sato, 2000, Quantitative genetic variation in CD19 expression correlates with autoimmunity, J Immunol, 165, 6635, 10.4049/jimmunol.165.11.6635
Serpier, 1997, Antagonistic effects of interferon-gamma and interleukin-4 on fibroblast cultures, J Invest Dermatol, 109, 158, 10.1111/1523-1747.ep12319207
Sparwasser, 1997, Bacterial DNA causes septic shock, Nature, 386, 336, 10.1038/386336a0
Tsuji-Yamada, 2001, Effect of IL-12 encoding plasmid administration on tight-skin mouse, Biochem Biophys Res Commun, 280, 707, 10.1006/bbrc.2000.4171
Van Uden, 1999, Immunostimulatory DNA and applications to allergic disease, J Allergy Clin Immunol, 104, 902, 10.1016/S0091-6749(99)70066-7
Wallace, 1994, A role for CD4+ T cells in the pathogenesis of skin fibrosis in tight skin mice, Eur J Immunol, 24, 1463, 10.1002/eji.1830240634
Zimmermann, 1998, CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis, J Immunol, 160, 3627