Corticosteroids enhance CD8+ T cell–mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1

Journal of Allergy and Clinical Immunology - Tập 121 - Trang 864-871.e4 - 2008
Hiroshi Ohnishi1, Nobuaki Miyahara1, Azzeddine Dakhama1, Katsuyuki Takeda1, Steven Mathis2, Bodduluri Haribabu2, Erwin W. Gelfand1
1Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colo
2James Graham Brown Cancer Center and Department of Microbiology and Immunology, University of Louisville Health Sciences Center, Louisville, Ky

Tài liệu tham khảo

Samuelsson, 1987, Leukotrienes and lipoxins: structures, biosynthesis, and biological effects, Science, 237, 1171, 10.1126/science.2820055 Yokomizo, 1997, A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis, Nature, 387, 620, 10.1038/42506 Tager, 2003, BLT1 and BLT2: the leukotriene B4 receptors, Prostaglandins Leukot Essen Fatty Acids, 69, 123, 10.1016/S0952-3278(03)00073-5 Kim, 2006, A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis, J Exp Med, 203, 829, 10.1084/jem.20052349 Huang, 1998, Molecular and biological characterization of the murine leukotriene B4 receptor expressed on eosinophils, J Exp Med, 188, 1063, 10.1084/jem.188.6.1063 Tager, 2000, BLTR mediates leukotriene B4-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis, J Exp Med, 192, 439, 10.1084/jem.192.3.439 Aiello, 2002, Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice, Arterioscler Thromb Vasc Biol, 22, 443, 10.1161/hq0302.105593 Lundeen, 2006, Leukotriene B4 receptors BLT1 and BLT2: expression and function in human and murine mast cells, J Immunol, 177, 3439, 10.4049/jimmunol.177.5.3439 Del Prete, 2007, Regulation of dendritic cell migration and adaptive immune response by leukotriene B4 receptors: a role for LTB4 in up-regulation of CCR7 expression and function, Blood, 109, 626, 10.1182/blood-2006-02-003665 Tager, 2003, Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment, Nat Immunol, 4, 982, 10.1038/ni970 Goodarzi, 2003, Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues, Nat Immunol, 4, 965, 10.1038/ni972 Ott, 2003, Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4, Nat Immunol, 4, 974, 10.1038/ni971 Griffiths, 1995, Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis, Proc Natl Acad Sci U S A, 92, 517, 10.1073/pnas.92.2.517 Medoff, 2005, BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation, J Exp Med, 202, 97, 10.1084/jem.20042481 Suzuki, 1999, The leukotriene B4 receptor antagonist ONO-4057 inhibits nephrotoxic serum nephritis in WKY rats, J Am Soc Nephrol, 10, 264, 10.1681/ASN.V102264 Bäck, 2005, Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia, Proc Natl Acad Sci U S A, 102, 17501, 10.1073/pnas.0505845102 Miyahara, 2005, Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness, J Immunol, 174, 4979, 10.4049/jimmunol.174.8.4979 Miyahara, 2005, Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness, Am J Respir Crit Care Med, 172, 161, 10.1164/rccm.200502-205OC Terawaki, 2005, Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses, J Immunol, 175, 4217, 10.4049/jimmunol.175.7.4217 Islam, 2006, The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans, Blood, 107, 444, 10.1182/blood-2005-06-2362 Taube, 2006, The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness, J Immunol, 176, 3157, 10.4049/jimmunol.176.5.3157 Gelfand, 2006, CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma, J Allergy Clin Immunol, 117, 577, 10.1016/j.jaci.2005.12.1340 Sallusto, 1999, Two subsets of memory T lymphocytes with distinct homing potentials and effector functions, Nature, 401, 708, 10.1038/44385 Masopust, 2001, Preferential localization of effector memory cells in nonlymphoid tissue, Science, 291, 2413, 10.1126/science.1058867 Manjunath, 2001, Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes, J Clin Invest, 108, 871, 10.1172/JCI13296 Weninger, 2001, Migratory properties of naive, effector, and memory CD8+ T cells, J Exp Med, 194, 953, 10.1084/jem.194.7.953 Backman, 1997, Airways obstruction in patients with long-term asthma consistent with “irreversible asthma.”, Chest, 112, 1234, 10.1378/chest.112.5.1234 Ulrik, 1999, Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma, Eur Respir J, 14, 892, 10.1034/j.1399-3003.1999.14d27.x Taniguchi, 2002, The decline of pulmonary function among patients with chronic asthma treated with inhaled corticosteroid, J Asthma, 39, 217, 10.1081/JAS-120002471 Stankova, 2002, Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival, J Immunol, 168, 3570, 10.4049/jimmunol.168.7.3570 Obinata, 2003, Glucocorticoids up-regulate leukotriene B4 receptor-1 expression during neutrophilic differentiation of HL-60 cells, Biochem Biophys Res Commun, 309, 114, 10.1016/S0006-291X(03)01554-7 Fernández-Ruiz, 1989, IL-2 protects T cell hybrids from the cytolytic effect of glucocorticoids. Synergistic effect of IL-2 and dexamethasone in the induction of high-affinity IL-2 receptors, J Immunol, 143, 4146, 10.4049/jimmunol.143.12.4146 Corrigan, 1993, CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5. Effect of glucocorticoid therapy, Am Rev Respir Dis, 147, 540, 10.1164/ajrccm/147.3.540 Miyahara, 2004, Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness, Nat Med, 10, 865, 10.1038/nm1081 Takeda, 1997, Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice, J Exp Med, 186, 449, 10.1084/jem.186.3.449 Oshiba, 1996, Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice, J Clin Invest, 97, 1398, 10.1172/JCI118560 Woo, 2003, Transepithelial migration of neutrophils in response to leukotriene B4 is mediated by a reactive oxygen species-extracellular signal-regulated kinase-linked cascade, J Immunol, 170, 6273, 10.4049/jimmunol.170.12.6273 Kato, 2000, Cell-specific transcriptional regulation of human leukotriene B4 receptor gene, J Exp Med, 192, 413, 10.1084/jem.192.3.413 Chan, 1998, Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma, J Allergy Clin Immunol, 101, 594, 10.1016/S0091-6749(98)70165-4 Szefler, 2002, Significant variability in response to inhaled corticosteroids for persistent asthma, J Allergy Clin Immunol, 109, 410, 10.1067/mai.2002.122635 Adcock, 2003, Corticosteroid-insensitive asthma: molecular mechanisms, J Endocrinol, 178, 347, 10.1677/joe.0.1780347 Loke, 2002, Glucocorticoid-resistant asthma, Curr Allergy Asthma Rep, 2, 144, 10.1007/s11882-002-0009-y National Institutes of Health, National Heart, Lung and Blood Institute, 2002 British Thoracic Society, 2003, Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma, Thorax, 58, i1 Lindsay, 1998, Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation, J Leukoc Biol, 64, 555, 10.1002/jlb.64.4.555 Lamas, 1997, Identification of a novel glucocorticoid response unit (GRU) in the 5′-flanking region of the mouse IL-2 receptor alpha gene, Cytokine, 9, 973, 10.1006/cyto.1997.0248 Bianchi, 2000, Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids, Proc Natl Acad Sci U S A, 97, 9573, 10.1073/pnas.160099797 Nemoto, 1995, Differences in the interleukin-2 (IL-2) receptor system in human and mouse: alpha chain is required for formation of the functional mouse IL-2 receptor, Eur J Immunol, 25, 3001, 10.1002/eji.1830251102 Kemeny, 1999, CD8+ T cell subsets and chronic obstructive pulmonary disease, Am J Respir Crit Care Med, 160, S33, 10.1164/ajrccm.160.supplement_1.10 Marian, 2006, Up-regulated membrane and nuclear leukotriene B4 receptors in COPD, Chest, 129, 1523, 10.1378/chest.129.6.1523