Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation

Harding, 1990, Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation, Nature, 346, 574, 10.1038/346574a0 Demotz, 1990, The minimal number of class II MHC-antigen complexes needed for T cell activation, Science, 249, 1028, 10.1126/science.2118680 Rudensky, 1991, Sequence analysis of peptides bound to MHC class II molecules, Nature, 353, 622, 10.1038/353622a0 Hunt, 1992, Peptides presented to the immune system by the murine class II major histocompatability complex molecule I-Ad, Science, 256, 1817, 10.1126/science.1319610 Monks, 1998, Three-dimensional segregation of supramolecular activation clusters in T cells, Nature, 395, 82, 10.1038/25764 Grakoui, 1999, The immunological synapse: A molecular machine controlling T-cell activation, Science, 285, 221, 10.1126/science.285.5425.221 Lee, 2002, Tyrosine kinase signaling precedes formation of the immunological synapse, Science, 295, 1539, 10.1126/science.1067710 Stinchcombe, 2001, The immunological synapse of CTL contains a secretory domain and membrane bridges, Immunity, 15, 751, 10.1016/S1074-7613(01)00234-5 van der Merwe, 2000, Cytoskeletal polarization and redistribution of cell-surface molecules during T-cell antigen recognition, Semin. Immunol., 12, 5, 10.1006/smim.2000.0203 Wülfing, 2002, Costimulation and endogenous MHC ligands contribute to T-cell recognition, Nat. Immunol., 3, 42, 10.1038/ni741 Qi, 2001, Synaptic pattern formation during cellular recognition, Proc. Natl. Acad. Sci. U. S. A., 98, 6548, 10.1073/pnas.111536798 Dustin, 1997, Antigen receptor engagement delivers a stop signal to migrating T lymphocytes, Proc. Natl. Acad. Sci. U. S. A., 94, 3909, 10.1073/pnas.94.8.3909 Chakraborty, 2002, How and why does the immunological synapse form?, Physical chemistry meets cell biology. Sci STKE, PE10 Springer, 1990, Adhesion receptors of the immune system, Nature, 346, 425, 10.1038/346425a0 Staunton, 1990, The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus, Cell, 61, 243, 10.1016/0092-8674(90)90805-O Xiong, 2001, Crystal structure of the extracellular segment of integrin αVβ3, Science, 294, 339, 10.1126/science.1064535 Garboczi, 1996, Structure of the complex between human T-cell receptor, viral peptide and HLA-A2, Nature, 384, 134, 10.1038/384134a0 Garcia, 1996, An αβ T-cell receptor structure at 2.5Å resolution and its orientation in the TCR–MHC complex, Science, 274, 209, 10.1126/science.274.5285.209 Shaw, 1997, Making the T-cell receptor go the distance: a topological view of T-cell activation, Immunity, 6, 361, 10.1016/S1074-7613(00)80279-4 Safran, 1994 Moy, 1994, Intermolecular forces and energies between ligands and receptors, Science, 266, 257, 10.1126/science.7939660 Wülfing, 1998, A receptor/cytoskeletal movement triggered by costimulation during T-cell activation, Science, 282, 2266, 10.1126/science.282.5397.2266 Delon, 2001, Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin, Immunity, 15, 691, 10.1016/S1074-7613(01)00231-X Allenspach, 2001, ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse, Immunity, 15, 739, 10.1016/S1074-7613(01)00224-2 Valitutti, 1995, Serial triggering of many T-cell receptors by a few peptide–MHC complexes, Nature, 375, 148, 10.1038/375148a0 Itoh, 1999, Serial TCR engagement and down modulation by peptide: MHC molecule ligands: Relationship to the quality of individual TCR signaling events, J. Immunol., 162, 2073, 10.4049/jimmunol.162.4.2073 Wofsy, 2001, Calculations show substantial serial engagement of T-cell receptors, Biophys. J., 80, 606, 10.1016/S0006-3495(01)76041-9 Van Kampen, 1987 Hohenberg, 1977, Theory of dynamic critical phenomena, Rev. Mod. Phys., 49, 435, 10.1103/RevModPhys.49.435 Davis, 1998, Ligand recognition by αβ T-cell receptors, Annu. Rev. Immunol., 16, 523, 10.1146/annurev.immunol.16.1.523 Carlin, 2001, Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses, J. Exp. Med., 194, 1507, 10.1084/jem.194.10.1507 Micheletti, 2000, Supra-agonist peptides enhance the reactivation of memory CTL responses, J. Immunol., 165, 4264, 10.4049/jimmunol.165.8.4264 Manning, 1998, Alanine scanning mutagenesis of an αβ T-cell receptor: mapping the energy of antigen recognition, Immunity, 8, 413, 10.1016/S1074-7613(00)80547-6 Janeway, 1998, T-cell development, survival, and signalling: a new concept of the role of self-peptide: self-MHC complexes, The Immunologist, 6, 5 Williams, 1999, A kinetic threshold between negative and positive selection based on the longevity of the T-cell receptor–ligand complex, J. Exp. Med., 189, 1531, 10.1084/jem.189.10.1531 Sloan-Lancaster, 1996, Altered peptide ligand-induced partial T-cell activation: molecular mechanisms and role in T-cell biology, Annu. Rev. Immunol., 14, 1, 10.1146/annurev.immunol.14.1.1 Germain, 1999, The dynamics of T-cell receptor signaling: complex orchestration and the key roles of tempo and cooperation, Annu. Rev. Immunol., 17, 467, 10.1146/annurev.immunol.17.1.467 Evavold, 1992, Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T-cell hybridomas, J. Immunol., 148, 347, 10.4049/jimmunol.148.2.347 Racioppi, 1993, Peptide major histocompaitibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T-cell receptor-dependent intracellular signaling, J. Exp. Med., 177, 1047, 10.1084/jem.177.4.1047 Reay, 1994, Use of global amino acid replacements to define the requirements for MHC binding and T-cell recognition of moth cytochrome c (93-103), J. Immunol., 152, 3946, 10.4049/jimmunol.152.8.3946 Kalergis, 2001, Efficient T-cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex, Nat. Immunol., 2, 229, 10.1038/85286 Matsui, 1994, Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness, Proc. Natl. Acad. Sci. U. S. A., 91, 12862, 10.1073/pnas.91.26.12862 Corr, 1994, T-cell receptor-MHC class I peptide interactions: affinity, kinetics and specificity, Science, 265, 946, 10.1126/science.8052850 Alam, 1996, T-cell-receptor affinity and thymocyte positive selection, Nature, 381, 616, 10.1038/381616a0 Lyons, 1996, A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists, Immunity, 5, 53, 10.1016/S1074-7613(00)80309-X Hudrisier, 1998, The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement, J. Immunol., 161, 553, 10.4049/jimmunol.161.2.553 Kersh, 1998, High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling, Immunity, 9, 817, 10.1016/S1074-7613(00)80647-0 Sykulev, 1998, Peptide antagonism and T-cell receptor interactions with peptide–MHC complexes, Immunity, 9, 475, 10.1016/S1074-7613(00)80631-7 Ding, 1999, Four A6–TCR/peptide/HLA–A2 structures that generate very different T-cell signals are nearly identical, Immunity, 11, 45, 10.1016/S1074-7613(00)80080-1 Rosette, 2001, The impact of duration versus extent of TCR occupancy on T-cell activation: a revision of the kinetic proofreading model, Immunity, 15, 59, 10.1016/S1074-7613(01)00173-X McKeithan, 1995, Kinetic proofreading in T-cell receptor signal transduction, Proc. Natl. Acad. Sci. U. S. A., 92, 5042, 10.1073/pnas.92.11.5042 Rabinowitz, 1996, Kinetic discrimination in T-cell activation, Proc. Natl. Acad. Sci. U. S. A., 93, 1401, 10.1073/pnas.93.4.1401 Reich, 1997, Ligand-specific oligomerization of T-cell receptor molecules, Nature, 387, 617, 10.1038/42500 Germain, 1997, T-cell signaling: the importance of receptor clustering, Curr. Biol., 7, R640, 10.1016/S0960-9822(06)00323-X Martz, 1982, The role of calcium in the lethal hit of T lymphocyte-mediated cytolysis, Adv. Exp. Med. Biol., 146, 121, 10.1007/978-1-4684-8959-0_9 Spits, 1986, Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells, Science, 232, 403, 10.1126/science.3485822 Shaw, 1986, Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones, Nature, 323, 262, 10.1038/323262a0 van Der Merwe, 2002, Immunology. The immunological synapse – a multitasking system, Science, 295, 1479, 10.1126/science.1069896 Alam, 1996, T-cell-receptor affinity and thymocyte positive selection, Nature, 381, 616, 10.1038/381616a0 Hogquist, 1994, T-cell receptor antagonist peptides induce positive selection, Cell, 76, 17, 10.1016/0092-8674(94)90169-4 Hogquist, 1995, Strong agonist ligands for the T-cell receptor do not mediate positive selection of functional CD8+ T cells, Immunity, 3, 79, 10.1016/1074-7613(95)90160-4 Sykulev, 1994, Kinetics and affinity of reactions between an antigen-specific T-cell receptor and peptide–MHC complexes, Immunity, 1, 15, 10.1016/1074-7613(94)90005-1