Correlation between EGFR Y1068 tyrosine phosphorylation and AP-1 activation by tumor promoter 12-O-tetradecanoylphorbol-13-acetate in mouse skin

Abe, 2006, Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro, Br. J. Pharmacol., 147, 402, 10.1038/sj.bjp.0706634 Baer-Dubowska, 1997, Mouse skin model as a reliable short-term carcinogenesis assay, Acta Pol. Toxicol., 5, 9 Chen, 2001, Transactivation of the Epidermal Growth Factor Receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction, J. Biol. Chem., 276, 46722, 10.1074/jbc.M107156200 DiGiovanni, 1992, Multistage carcinogenesis in mouse skin, Pharmacol. Ther., 54, 19, 10.1016/0163-7258(92)90051-Z Kiguchi, 1998, Altered expression of epidermal growth factor receptor ligands in tumor promoter-treated mouse epidermis and in primary mouse skin tumors induced by an initiation–promotion protocol, Mol. Carcinog., 22, 73, 10.1002/(SICI)1098-2744(199806)22:2<73::AID-MC2>3.0.CO;2-L Laurent-Puig, 2009, Mutations and response to epidermal growth factor receptor inhibitors, Clin. Cancer Res., 15, 1133, 10.1158/1078-0432.CCR-08-0905 Lee, 2007, Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-κB and AP-1: IκB kinase and c-Jun-N-terminal kinase as respective potential upstream targets, Carcinogenesis, 28, 1491, 10.1093/carcin/bgm054 Cichocki, 2008, Pterostilbene is equally potent as resveratrol in inhibiting 12-O-tetradecanoylphorbol-13-acetate activated NF-κB, AP-1, COX-2, and iNOS in mouse epidermis, Mol. Nutr. Food Res., 52, S62 Ke, 2010, The c-Jun-NH2 -terminal kinase 2 plays a dominant role in human epidermal neoplasia, Cancer Res., 70, 3080, 10.1158/0008-5472.CAN-09-2923 Oehler, 1993, Mutation of a phosphorylation site in the DNA-binding domain is required for redox-independent transactivation of AP-1-dependent genes by v-Jun, Oncogene, 8, 1141 Pulverer, 1991, Phosphorylation of c-jun mediated by MAP kinases, Nature, 353, 670, 10.1038/353670a0 Renard, 2001, Development of a sensitive multi-well colorimetric assay for active NFkappaB, Nucleic Acids Res., 29, E21, 10.1093/nar/29.4.e21 Rho, 1994, Altered expression of the epidermal growth factor receptor and transforming growth factor-α during multistage skin carcinogenesis in SENCAR mice, Mol. Carcinog., 11, 19, 10.1002/mc.2940110105 Saez, 1995, c-fos is required for malignant progression of skin tumors, Cell, 82, 721, 10.1016/0092-8674(95)90469-7 Segrelles, 2002, Functional roles of Akt signaling in mouse skin tumorigenesis, Oncogene, 21, 53, 10.1038/sj.onc.1205032 Sharma, 2010, RasGRP1 is essential for ras activation by tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes, J. Biol. Chem., 285, 15724, 10.1074/jbc.M109.100016 Szaefer, 2007, The effect of plant phenols on the expression and activity of phorbol ester induced PKC in mouse epidermis, Toxicology, 230, 1, 10.1016/j.tox.2006.10.001 Szamałek, 2007, RasGRP proteins – Ras activating factors, Adv. Biochem., 53, 112 Tang, 2000, Both (+/−)syn- and (+/−)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at codon 61 of c-H-ras, Cancer Res., 60, 5688 Xian, 1995, Activation of Epidermal Growth Factor Receptor by skin tumor promoters and in skin tumors from SENCAR mice, Cell Growth Differ., 6, 1447 Weyergang, 2007, Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor, Biochem. Pharmacol., 74, 226, 10.1016/j.bcp.2007.04.018 Whitmarsh, 1996, Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways, J. Mol. Med., 74, 589, 10.1007/s001090050063 Yuspa, 1994, The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis. 33rd G.H.A. Clowes Memorial Award Lecture, Cancer Res., 54, 1178