Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thrombogram parameters

Blood Coagulation and Fibrinolysis - Tập 19 Số 3 - Trang 183-189 - 2008
Joost J. van Veen1,2,3,4, Alex Gatt1,2,3,4, Photographer Bob Cooper1,2,3,4, Steven Kitchen1,2,3,4, Annette Bowyer1,2,3,4, Michael Makris1,2,3,4
1Sheffield Haemophilia and Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, UK
2e-mail: [email protected]
3fax: +44 114 2756126
4to J.J. van Veen, Sheffield Haemophilia and Thrombosis Centre, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2 JF, UK Tel: +44 115 2712500

Tóm tắt

Từ khóa


Tài liệu tham khảo

Mann, 2003, What is all that thrombin for?, J Thromb Haemost, 1, 1504, 10.1046/j.1538-7836.2003.00298.x

Girolami, 2004, Thrombosis-free surgical procedures in severe (Homozygote) factor XII deficiency: report of four additional cases and literature review [review] [32 refs], Clin Appl Thromb Hemost, 10, 351, 10.1177/107602960401000407

Colman, 1997, Contact System: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes, Blood, 90, 3819, 10.1182/blood.V90.10.3819

Rand, 1996, Blood clotting in minimally altered whole blood, Blood, 88, 3432, 10.1182/blood.V88.9.3432.bloodjournal8893432

Hemker, 2000, The thrombogram: monitoring thrombin generation in platelet-rich plasma, Thromb Haemost, 83, 589, 10.1055/s-0037-1613868

Hemker, 2003, Calibrated automated thrombin generation measurement in clotting plasma, Pathophysiol Haemost Thromb, 33, 4, 10.1159/000071636

Keularts, 2001, The role of factor XI in thrombin generation induced by low concentrations of tissue factor, Thromb Haemost, 85, 1060, 10.1055/s-0037-1615964

Beltran-Miranda, 2005, Thrombin generation and phenotypic correlation in haemophilia A, Haemophilia, 11, 326, 10.1111/j.1365-2516.2005.01107.x

Dargaud, 2005, Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B, Thromb Haemost, 93, 475, 10.1160/TH04-10-0706

Chantarangkul, 2003, Thrombin generation assessed as endogenous thrombin potential in patients with hyper- or hypo-coagulability, Haematologica, 88, 547

Dargaud, 2006, Elimination of contact factor activation improves measurement of platelet-dependent thrombin generation by calibrated automated thrombography at low-concentration tissue factor, J Thromb Haemost, 4, 1160, 10.1111/j.1538-7836.2006.01905.x

Luddington, 2004, Clinical measurement of thrombin generation by calibrated automated thrombography requires contact factor inhibition, J Thromb Haemost, 2, 1954, 10.1111/j.1538-7836.2004.00964.x

McIntosh, 2003, A modified thrombin generation test for the measurement of factor VIII concentrates, J Thromb Haemost, 1, 1005, 10.1046/j.1538-7836.2003.00209.x

Kamphuisen, 2001, Elevated factor VIII levels and the risk of thrombosis, Arterioscler Thromb Vasc Biol, 21, 731, 10.1161/01.ATV.21.5.731

O'Donnell, 2001, Elevated plasma factor VIII levels – a novel risk factor for venous thromboembolism, Clin Lab, 47, 1

O'Donnell, 2001, Marked elevation of thrombin generation in patients with elevated FVIII:C and venous thromboembolism, Br J Haematol, 115, 687, 10.1046/j.1365-2141.2001.03146.x

Schonauer, 2003, The effect of beta-receptor blockade on factor VIII levels and thrombin generation in patients with venous thromboembolism, Thromb Haemost, 89, 837, 10.1055/s-0037-1613470

Barrowcliffe, 1984, Methodology of the two-stage assay of Factor VIII, Scand J Haematol, 41, 25, 10.1111/j.1600-0609.1984.tb02765.x

Sorensen, 2004, Whole blood clot formation phenotypes in hemophilia A and rare coagulation disorders. Patterns of response to recombinant factor VIIa, J Thromb Haemost, 2, 102, 10.1111/j.1538-7836.2004.00528.x