Copper(I)‐Catalyzed Azide–Alkyne Cycloadditions in Microflow: Catalyst Activity, High‐T Operation, and an Integrated Continuous Copper Scavenging Unit

Wiley - Tập 5 Số 9 - Trang 1703-1707 - 2012
Alvaro Carlos Varas1, Timothy Noël1, Qi Wang1, Volker Hessel1
1Department of Chemical Engineering and Chemistry Eindhoven University of Technology Den Dolech 2 5600 MB Eindhoven The Netherlands

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Triazole collected as described in Figure 4 was loaded in a glass syringe and combined in flow with aq. EDTA solution to establish a slug flow regime. The biphasic stream was next delivered to an Asia FLLEX extraction module.