Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

PLoS Medicine - Tập 5 Số 5 - Trang e114
Timothy A. Chan1,2,3,4, Sabine C. Glöckner1,5,4,6, Joo Mi Yi1,4, Wei Chen7,1,4,8, Leander Van Neste9, Leslie Cope7,10, James G. Herman1,4, Victor E. Velculescu7,11,12,13, Kornel E. Schuebel1,4, Joseph M. Herman1,5,4,6, Stephen B. Baylin7,1,4,8
1Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore
2Department of Radiation Oncology and Molecular Radiation Sciences, The Johns
3Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
4Maryland, United States of America
5Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland, United
6States of America
7Baltimore, Maryland, United States of America
8Predoctoral Training Program in Human Genetics, The Johns Hopkins University
9Department of Molecular Biotechnology, Ghent University, Ghent, Belgium
10Biometry and Clinical Trials Division, The Johns Hopkins Kimmel Cancer Center
11Cancer Center, Baltimore, Maryland, United States of America
12Howard Hughes Medical Institute at The Johns Hopkins Kimmel Cancer Center
13Ludwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Kimmel

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PLoS Medicine

Tập 5 Số 5

e114

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