Controversies over the diagnosis of oligodendroglioma: a report from the satellite workshop at the 4th international symposium of brain tumor pathology, Nagoya Congress Center, May 23, 2012

Takashi Komori1,2,3, Takanori Hirose4,5, Makoto Shibuya6,7, Hiroyoshi Suzuki8, Shinya Tanaka9, Atsushi Sasaki10
1Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
2Department of Pathology, Graduate School of Medicine, Tokyo Women’s Medical University, Tokyo, Japan
3Brain Pathology Research Center, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
4Pathology for Regional Communication, Kobe University, Kobe, Japan
5Department of Pathology, Tokushima Prefectural Central Hospital, Tokushima, Japan
6Central Laboratory, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan
7Department of Pathology, Ibaragi Medical Center, Tokyo Medical University, Tokyo, Japan
8Department of Laboratory Medicine and Pathology, Sendai Medical Center, Sendai, Japan
9Department of Cancer Pathology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
10Department of Pathology, Saitama Medical University, Saitama, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Bailey P, Cushing H (1926) A classification of tumors of the glioma group on a histogenetic basis with a correlated study of prognosis. JB Lippincott, Philadelphia

Baily P, Bucy PC (1929) Oligodendrogliomas of the brain. J Pathol Bacteriol 32:735–751

Kros JM, Gorlia T, Kouwenhoven MC et al (2007) Panel review of anaplastic oligodendroglioma from European organization for research and treatment of cancer trial 26951: assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome. J Neuropathol Exp Neurol 66:545–551

Cairncross JG, Ueki K, Zlatescu MC et al (1998) Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90:1473–1479

Aldape K, Burger PC, Perry A (2007) Clinicopathologic aspects of 1p/19q loss and the diagnosis of oligodendroglioma. Arch Pathol Lab Med 131:242–251

Jenkins RB, Blair H, Ballman KV et al (2006) A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res 66:9852–9861

Bettegowda C, Agrawal N, Jiao Y et al (2011) Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 333:1453–1455

Ichimura K (2012) Molecular pathogenesis of IDH mutations in gliomas. Brain Tumor Pathol 29:131–139

van den Bent MJ, Brandes AA, Taphoorn MJ et al (2013) Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J Clin Oncol 31:344–350

Cairncross G, Wang M, Shaw E et al (2013) Phase III trial of chemo radiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol 31:337–343

Giannini C, Burger PC, Berkey BA et al (2008) Anaplastic oligodendroglial tumors: refining the correlation among histopathology, 1p 19q deletion and clinical outcome in Intergroup Radiation Therapy Oncology Group Trial 9402. Brain Pathol 18:360–369

Zülch KJ (1957) Brain tumors: their biology and pathology. Springer, New York

van den Bent MJ, Carpentier AF, Brandes AA et al (2006) Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer Phase III Trial. J Clin Oncol 24:2715–2722

Perry A, Aldape KD, George DH et al (2004) Small cell astrocytoma: an aggressive variant that is clinicopathologically and genetically distinct from anaplastic oligodendroglioma. Cancer 101:2318–2326

Louis DN, Ohgaki H, Wiestler OD et al (2007) Who classification of tumours of the central nervous system, 4th edn. IARC Press, Lyon

Miller CR, Dunham CP, Scheithauer BW et al (2006) Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas. J Clin Oncol 24:5419–5426

Hegi ME, Janzer RC, Lambiv WL et al (2012) Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial. Acta Neuropathol 123:841–852

Pinto LW, Araujo MB, Vettore AL et al (2008) Glioblastomas: correlation between oligodendroglial components, genetic abnormalities, and prognosis. Virchows Arch 452:481–490

Senetta R, Verdun di Cantogno L, Chiusa L et al (2013) A “weighted” fluorescence in situ hybridization strengthens the favorable prognostic value of 1p/19q codeletion in pure and mixed oligodendroglial tumors. J Neuropathol Exp Neurol 72:432–441