Kích thích buồng trứng có kiểm soát và bổ sung progesterone ảnh hưởng đến vi sinh vật âm đạo và nội mạc tử cung trong các chu kỳ thụ tinh trong ống nghiệm: một nghiên cứu thí điểm
Tóm tắt
Kích thích buồng trứng có kiểm soát (COS) và bổ sung progesterone (P) có làm thay đổi vi sinh vật âm đạo và nội mạc tử cung ở phụ nữ tiến hành thụ tinh ống nghiệm không?
Mười lăm phụ nữ đã được phân tích vi sinh vật tại hai thời điểm: trong một lần chuyển phôi giả được thực hiện ở giai đoạn hoàng thể của chu kỳ trước COS, và tại thời điểm chuyển phôi tươi (ET). Một mẫu dịch âm đạo và đầu xa của ống chuyển phôi được phân tích bằng phương pháp giải trình tự gen 16SrRNA thế hệ mới. Sự đa dạng của vi sinh vật được đánh giá dựa trên cả chỉ số tương đồng Bray-Curtis và chỉ số đa dạng Shannon.
Từ khóa
#Kích thích buồng trứng có kiểm soát #bổ sung progesterone #vi sinh vật âm đạo #vi sinh vật nội mạc tử cung #thụ tinh ống nghiệmTài liệu tham khảo
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