Control and eradication of foot-and-mouth disease

Virus Research - Tập 91 Số 1 - Trang 101-144 - 2003
P. Sutmöller1, Simon S Barteling2, R. Casas Olascoaga3, Keith Sumption4
1Animal Health Consultant, Panamerican Foot and Mouth Disease Center PAHO/WHO, Brazil.
2Consultant Veterinary Vaccines, former Head Department FMD Vaccine Development, and Production ID-Lelystad and former Head Community Co-ordinating Institute (for the EU), The Netherlands
3Direct Advisor of the Minister of Livestock, Agriculture and Fisheries, Uruguay, former Director of the Panamerican Foot and Mouth Disease Center PAHO/WHO, Brazil
4Lecturer in International Animal Health, Centre for Tropical Veterinary Medicine, University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG, Scotland, UK

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Abaracon, 1980, Protection of cattle following vaccination with oil adjuvanted foot-and-mouth disease vaccine, Bol. Centr. Panam. Fiebre Aftosa, 37–38, 45

Alonso, 1990, Detection of foot-and-mouth disease virus infected-associated antigen antibodies: comparison of the enzyme-linked immunosorbent assay and agar gel immunodiffusion tests, Prev. Vet. Med., 9, 223, 10.1016/0167-5877(90)90069-T

Anderson, 1976, The role of sheep and goats in the epizootiology of foot-and-mouth disease in Kenya, J. Hyg., 76, 395, 10.1017/S0022172400055315

Anderson, 1975, The pathogenity of bovine strains of foot and mouth disease virus for impala and wildebeest, J. Wildl. Dis., 11, 248, 10.7589/0090-3558-11.2.248

Anderson, 1974, The effect of repeated vaccination in an enzootic foot-and-mouth disease area on the incidence of virus carrier cattle, J. Hyg., 73, 229, 10.1017/S0022172400024062

Anderson, 1979, The pathogenesis of foot-and-mouth disease in the African buffalo (Syncerus caffer) and the role of this species in the epidemiology of the disease in Kenya, J. Comp. Path., 89, 541, 10.1016/0021-9975(79)90045-8

Anon, 1969. Report of the Committee of Inquiry on Foot-and-Mouth Disease, 1968. Part 1 and 2. Her Majesty's Stationery Office, London, 135.

Anon, 1998. Proceedings of the Final Meeting of Concerted Action CT 93 0909, Veterinary Quarterly, 20, Supplement 2, May 1998.

Anon, 2001. The FMD epidemic: strengths and weaknesses of epidemiological modelling. The Veterinary Record, November 3rd, 539–541.

Archetti, 1995, Detection of foot-and-mouth disease virus-infected cattle by assessment of antibody response in oropharyngeal fluids, J. Clin. Microbiol., 33, 79, 10.1128/JCM.33.1.79-84.1995

Auge de Mello, 1977, Anamnestic response in cattle after revaccination with oil adjuvanted foot-and-mouth disease vaccines, Bol. Centr. Panam. Fiebre Aftosa, 27–28, 55

Auge de Mello, 1979, Reflections on the prevention of foot-and-mouth disease in swine, Bol. Centr. Panam. Fiebre Aftosa, 39–36, 59

Auge de Mello, 1982, The use of oil-adjuvanted foot-and-mouth disease vaccine in endemic areas, Bol. Centr. Panam. Fiebre Aftosa, 45–46, 33

Auge de Mello, 1977, Immune response of adult cattle vaccinated with oil-adjuvanted foot-and-mouth disease vaccines, Bol. Centr. Panam. Fiebre Aftosa, 26, 27

Auge de Mello, 1975, Field application of inactivated oil-adjuvanted foot-and-mouth disease virus vaccine: vaccination and revaccination of young cattle, Bol. Centr. Panam. Fiebre Aftosa, 19–20, 39

Auge de Mello, 1978, Foot-and-mouth disease oil-adjuvanted vaccines for pigs. 1. Double emulsion vaccine applied by different routes, Bol. Centr. Panam. Fiebre Aftosa, 31–32, 7

Auge de Mello, 1978, Foot-and-mouth disease oil-adjuvanted vaccine for pigs. 11. Intraperitoneal vaccination of young pigs with double emulsion vaccine, Bol. Centr. Panam. Fiebre Aftosa, 31–32, 21

Auge de Mello, 1989, The vaccination of young cattle with an oil adjuvant foot-and-mouth disease vaccine, Bol. Centr. Panam. Fiebre Aftosa, 55, 9

Auge de Mello, 1980, Persistence of antibody response after revaccination with oil-adjuvanted foot-and-mouth disease vaccine, Bol. Centr. Panam. Fiebre Aftosa, 37–38, 39

Bachrach, 1968, Foot and mouth disease, Annu. Rev. Microbiol., 22, 201, 10.1146/annurev.mi.22.100168.001221

Bahnemann, 1975, Binary ethylenimine as an inactivant for foot-and-mouth disease and its application for vaccines production, Arch. Virol., 47, 47, 10.1007/BF01315592

Bang, 1912, Foot-and-mouth disease, J. Comp. Path., 25, 1, 10.1016/S0368-1742(12)80001-4

Barnet, 1999, The role of small ruminants in the epidemiology and transmission of foot-and-mouth disease, Vet. J., 158, 6, 10.1053/tvjl.1998.0338

Barteling, S.J., Leeuw, P.W. de, 1979. The use of stored concentrated antigens for the preparation of foot-and-mouth disease vaccines. Res. Group Eur. Comm. Contr. FMD, Lindholm, Denm, FAO, Rome, 51.

Barteling, S.J., Sugimori, T., Leeuw, P.W. de, 1979. Vaccination experiments in cattle and pigs with foot-and-mouth disease vaccines prepared from polyethylene-glycol-purified virus produced in growing BHK-suspended cell cultures. Bull. Off. Int. Epiz. 91, 101.

Barteling, 1984, Formaldehyde inactivation of foot-and-mouth disease virus. Conditions for the preparation of safe vaccine, Arch. Virol., 80, 103, 10.1007/BF01310652

Barteling, 1991, Developments in foot-and-mouth disease vaccines. Review, Vaccine, 9, 75, 10.1016/0264-410X(91)90261-4

Barteling, S.J., Ismael Cassim, N., 2000. Formaldehyde increases the inactivation rate of foot-and-mouth disease virus at least a hundred-fold. Pep. Res. Gr. Comm. Contr. FMD, Borovits, Bulgaria. FAO Rome, p. 270.

Bastos, 1999, Possibility of sexual transmission of foot-and-mouth disease from African buffalo to cattle, Vet. Rec., 145, 77, 10.1136/vr.145.3.77

Bauer, K., Muller, H., Eissner, G., 1977. Untersuchungen zur epidemiologischen Bedeutung von Maul-und Klauenseuche (MKS-) Virusdauerausscheidertieren (Studies on the epidemiological importance of animals permanently excreting foot and mouth disease virus) Berliner und Munchener Tierarztliche Wochenschrift, 90 (1), 1–5.

Beck, 1987, Subtyping of European FMDV outbreaks by nucleotide sequence determination, J. Virol., 61, 1621, 10.1128/JVI.61.5.1621-1629.1987

van Bekkum, 1959, Observations on the carrier state of cattle exposed to foot-and-mouth disease virus, Tijdschr. Diergeneesk., 84, 1159

van Bekkum, 1966, Further information on the persistence of infective foot-and-mouth disease virus in cattle exposed to virulent virus strains, Bull. Off. Int. Epiz., 65, 1949

van Bekkum, 1967, Experience with the vaccination of pigs for the control of foot-and-mouth disease in The Netherlands, Tijdschr. Diergeneesk., 92, 87

Bergmann, 1998, Serodiagnostic strategy for estimation of foot-and-mouth disease viral activity through highly sensitive immunoassays using bioengineered nonstructural proteins, Vet. Q., 20, 56

Bergmann, 1993, Diagnosis of persistent aphthovirus infection and its differentiation from vaccination response in cattle by use of enzyme-linked immunoelectrotransfer blot analysis with bio-engineered nonstructural viral antigens, Am. J. Vet. Res., 54, 825

Bergmann, 1996, Identification of foot-and-mouth disease virus free regions by use of a standardized enzyme-linked immunoelectrotransfer blot assay, Am. J. Vet. Res., 57, 972

Bergmann, 2000, Improvement of a serodiagnostic strategy for FMDV virus surveillance in cattle under systematic vaccination: a combined system of an indirect ELISA-3ABC with an enzyme-linked immunoelectrotransfer assay, Arch. Virol., 145, 473, 10.1007/s007050050040

Blood, 1951, Se establece el Centro Panamericano Anti-Aftosa, Turrialba, 1, 278

Boldrini, 1978, Vaccination and the control of foot-and-mouth disease, Vet. Rec., 102, 194

Brocchi, 1998, Diagnostic potential of Mab-based ELISAs for antibodies to nonstructural proteins of foot-and-mouth disease virus to differentiate infection from vaccination, Vet. Q., 20, 20, 10.1080/01652176.1998.9694957

Brooksby, J.B., Roger, J., 1957. In: Methods of Typing and Cultivation of Foot and Mouth Disease Viruses. Paris, pp. 31 (Project 208 of OEEG).

Brooskby, 1982, Portraits of viruses: foot-and-mouth disease virus, Intervirology, 18, 1, 10.1159/000149299

Bürgi, 1928, Les méthodes générales de la prophylaxie de la fiévre aphteuse, Bull. Off. Int. Epiz., 1, 564

Burrows, 1966, The infectivity assay of foot-and-mouth disease virus in pigs, J. Hyg. Camb., 66, 633, 10.1017/S0022172400028369

Burrows, 1968, Excretion of foot-and-mouth disease virus prior to the development of lesions, Vet. Rec., 82, 387

Burrows, 1968, The persistence of foot-and-mouth disease in sheep, J. Hyg., 10.1017/S0022172400028369

Cadena Santos, J., Estupinan, J.A., 1975. La fiebre Aftosa y otras Enfermedades Vesiculares en Colombia. ICA, Mayo, pp. 37–41.

Callahan, 2002, Rapid detection of foot-and-mouth disease virus using a portable real-time RT-PCR Assay, J. Am. Vet. Med. Assoc., 220, 1636, 10.2460/javma.2002.220.1636

Callens, M., Clercq, K. de, Gruia, M., Danes, M., 1998. Detection of foot-and-mouth disease by reverse transcription polymerase chain reaction and virus isolation in contact sheep without clinical signs of foot-and-mouth disease. Conference paper. Veterinary Quarterly 20 (Suppl. 2), S37–S40.

Capel-Edwards, 1970, Foot-and-mouth disease in the brown rat, J. Comp. Path., 80, 543, 10.1016/0021-9975(70)90051-4

Capstick, 1962, Growth of a cloned strain of hampter kidney cells in suspended culture and their susceptibility to the virus of FMD, Nature (Lond.), 195, 1163, 10.1038/1951163a0

Capstick, 1965, Production of foot-and-mouth disease virus antigen from BHK 21 clone 13 cells grown and infected in deep suspension cultures, Nature (Lond.), 205, 1135, 10.1038/2051135a0

Capstick, P.B., Telling, R.C., 1966. Production of FMD vaccine in BHK21 cells. In: FAO Rep. Meet. Res. Gp. Stand. Tech. Eur.Comm. Control FMD, Pirbright, England, September 14–16.

Casas Olascoaga, 1978, Summary of current research of Pan American foot-and-mouth disease center on oil adjuvanted vaccines, Bull. Off. Int. Epiz., 89, 1015

Casas Olascoaga, R., Gomes, I., Rosenberg, F.J., Auge de Mello, P., Astudillo, Vicente., Magallanes, N., 1999. Fiebre Aftosa, Book i-xv 1–458 Editora Atheneu, Sao Paulo.

Casas Olascoaga, 1984, Foot-and mouth disease policies and control strategies in South America, Prev. Vet. Med., 2, 341, 10.1016/0167-5877(84)90077-1

Casas Olascoaga, R., P., Auge de Mello, D., Abaracon, I., Gomes, A., Alonso, F., Mesquita, J.A., Darsie, G.C., Pinkoski, D.I., Guedes Deak, J., Gubel, J.G., Barbosa, J.R., 1990. Production and control of oil foot-and-mouth disease vaccines, at the Pan American foot-and-mouth disease center and the Regional Support Laboratory for Animal Health of the Ministry of Agricultural and Agrarian Reform, Brazil.

Condy, 1985, The duration of the foot-and-mouth disease virus carrier state in African buffalo (i) in the individual animal and (ii) in a free-living herd, Comp. Immunol. Microbiol. Infect. Dis., 8, 257, 10.1016/0147-9571(85)90004-9

Cottral, 1969, Persistence of foot-and-mouth disease virus in animals, their products and the environment, Bull. Off. Int. Epiz., 71, 549

Cowan, 1969, A third antigenic component associated with foot-and-mouth disease infection, Virology, 30, 528, 10.1016/0042-6822(66)90128-0

Cox, 1999, Emergency vaccination of sheep against foot-and-mouth disease: protection against disease and reduction in contact transmission, Vaccine, 17, 1858, 10.1016/S0264-410X(98)00486-1

Cunliffe, 1963, Formalin-treated foot-and-mouth disease virus: comparison of two adjuvants in cattle, Can. J. Comp. Med. Vet. Sci., 27, 193

Daggupaty, 1990, Airborne spread of foot-and-mouth disease in Saskatchewan, Canada, 1951–52, Can. J. Vet. Res., 54, 465

David, M., Torres, A., Mebus, C., Carrillo, Bj., Schudel, A.A., Fondevila, N., Blanco Viera, J., Marcovecchio, F., 1993. Further studies on foot and mouth disease virus in the llama (Llama glama). In: Proceedings of the Annual Meeting of the United States Animal Health Association (USAHA), 25 October, Las Vegas, Nevada. USAHA, Richmond, Virginia, pp. 280–285.

DeDiego, 1997, The non-structural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle, Arch. Virol., 142, 2021, 10.1007/s007050050219

DEFRA 2001. Report of the Chief Veterinary Officer to the FMD Stakeholders Meeting, 26 October, 2001.

Dekker, A., Nielen, M., Molendijk, M., Kroonenberg, F., 1996. Foot-and-mouth disease airborne transmission prediction model: data and model considerations. Report of the Session of the Research group of the European Commission for the Control of Foot-and-Mouth Disease, Kibbutz Ma'ale Hachamisha, Israel, 2–6 September 1996. FAO, Rome, pp. 176–182.

Dias, 1981, Tissue response in sheep vaccinated with oil-adjuvanted foot-and-mouth disease vaccine, Bol. Centr. Panam. Fiebre Aftosa, 41–42, 35

Doel, 1994, Emergency vaccination against foot-and-mouth disease: rate of development of immunity and its implications for the carrier state, Vaccine, 12, 592, 10.1016/0264-410X(94)90262-3

Doel, 1984, The stability and potency of vaccines prepared from inactivated foot-and-mouth disease virus concentrates, J. Biol. Stand., 12, 247, 10.1016/S0092-1157(84)80003-7

Domanski, R., Fitko, R., 1959. Disturbances of the pituitary and other hormonal glands in cows after foot-and-mouth disease. Proceedings of the 16th International Veterinary Congress, Madrid, pp. 421.

Donaldson, 1986, Aerobiology of foot-and-mouth diseases (FMD): an outline and recent advances, Rev. Sci. Tech. Off. Int., 5, 315, 10.20506/rst.5.2.234

Donaldson, 1979, Air-borne foot-and mouth disease, Vet. Rec., 49, 653

Donaldson, Alexanderssen, 2001. Relative resistance of pigs to infection by natural aersols. Vet. Rec., May 12th, 2001, 3, 600–602.

Donaldson, et al., 2001. The relative risks of uncontrollable (airborne) spread of FMD by different species. Vet. Rec., 12 May, 2001, 602–04.

Donaldson, 1972, The influence of relative humidity on the aerosol stability of different stains of foot-and-mouth disease virus suspended in saliva, J. Gen. Virol., 15, 25, 10.1099/0022-1317-15-1-25

Donaldson, 1983, Quantitative data on air-borne foot-and-mouth disease virus: its production, carriage and deposition, Phil. Trans. R. Soc. Lond. (B), 302, 529, 10.1098/rstb.1983.0072

Donaldson, 1970, Further investigations on the airborne excretion of foot-and-mouth disease virus, J. Hyg. Camb., 68, 557, 10.1017/S0022172400042480

Donalson, 2001, Relative risk of the uncontrollable (airborne) spread of FMD by different species, Vet. Rec., 148, 602, 10.1136/vr.148.19.602

Donn, 1994, Improved detection of persistent foot-and-mouth disease infection in cattle by polymerase chain reaction, J. Virol. Methods, 49, 179, 10.1016/0166-0934(94)90042-6

Dora, 1984, Epidemic of foot-and-mouth disease in Bage, RS, Brazil, 1980. Evaluation of two systems of vaccination, Bol. Centr. Panam. Fiebre Aftosa, 50, 11

Duchesne, 1982, The use of highly concentrated purified (by a large scale method) and long-term liquid nitrogen stored foot-and-mouth disease viruses for the preparation of vaccines: physico–chemical quality controls and potency tests after storage, Develop. Biol. Stand., 50, 249

Edwards, J.T., 1934. Further experiments with hedgehogs. Foot-and-Mouth Disease Research Committee, UK, Unpublished papers, Nos 214B and 223B.

Eskildsen, 1969, Experimental pulmonary infection of cattle with foot-and-mouth disease virus, Nord. Med. Vet., 21, 86

Esterhuysen, 1995, Buffalo in the northern Natal game parks show no serological evidence of infection with foot and mouth disease virus, Onderstepoort J. Vet. Res., 52, 63

Ferguson, N., Donnelly, C., Anderson, R., 2001. The foot-and-mouth epidemic in Great Britain: pattern of spread and impact of interventions. Published online 12; 10.1126/science. 1061020 (Science Express Reports).

Ferris, 1989, Experimental infection of eland (Taurotrages oryx), sable antelope (Ozanna grandicomis) and buffalo (Syncerus caffer) with foot-and-mouth disease virus, J. Comp. Path., 101, 307, 10.1016/0021-9975(89)90040-6

Flückiger, G., 1934. La lutte moderne contre la fiévre aphteuse. Proceedings of the 12th International Veterinary Congress, New York, 2, pp. 101–115.

Fogedby, E. Review of epizootiology and control of foot-and-mouth disease in Europe, 1937–1961. Eur. Comm. Control of FMD, FAO, Rome, 1963.

Forman, 1974, Studies with foot and mouth disease virus in British deer (red, fallow and roe) I. Clinical disease, J. Comp. Path., 84, 215, 10.1016/0021-9975(74)90062-0

Forman, 1974, Studies with foot and mouth disease virus in British deer (red, fallow and roe) II. Recovery of virus and serological response, J. Comp. Path., 84, 221, 10.1016/0021-9975(74)90063-2

Frenkel, 1947, La culture de virus de la fievre aphteuse sur l’épithelium de la langue des bovides, Off. Int. Epiz., 28, 155

Frenkel, 1951, Research on foot-and-mouth disease. II. The cultivation of the virus on a practical scale in explantations of bovine tongue epithelium, Am. J. Vet. Res., 12, 187

Gailiunas, 1966, Presence and persistence of foot-and-mouth disease virus in bovine skin, J. Bact., 91, 2333, 10.1128/JB.91.6.2333-2338.1966

Gibbens, 2001, Descriptive epidemiology of the 2001 foot-and-mouth disease epidemic in the Great Britain; the first five months, Vet. Rec., 149, 729, 10.1136/vr.149.24.729

Gibbs, E.P.J., Herniman, K.A.J., Lawman, M.J.P., Sellers, R.F., 1974. Foot and mouth disease in British deer: transmission of virus to cattle, sheep and deer. Vet. Rec. 28 June, 558–563.

Gibbs, Y.M., 1931. Susceptibility of different species of animals to foot-and-mouth disease. ii. Hedgehogs. In: Fourth Progress Report Foot-and-Mouth Disease Research Committee.

Gloster, 1982, Risk of air-borne spread of foot-and-mouth disease from the Continental to England, Vet. Rec., III, 290, 10.1136/vr.111.13.290

Gloster, 1981, Forecasting the air-borne spread of foot-and-mouth disease, Vet. Rec., 108, 370, 10.1136/vr.108.17.370

Goic Martinic, R., 1988. Evaluacion de la vacuna antiaftosa de adyuvante oleoso en Rio Grande do Sul, Brasil y en Uruguay, 1976–1987. Centr. Panam. Fiebre Aftosa, Rio de Janeiro, 1–76.

Goic, R. Historia de la Fiebre Aftosa en America del Sur. Confederacion Interamericana de Ganaderos (CIAGA). Informe del Primer Seminario Hemisferico sobre Sanidad Animal y Fiebre Aftosa. 1971, junio 16–20, 1–14 paginas, Panama.

Gomes, 1980, Persistence of circulating antibodies in swine revaccinated with oil-adjuvanted foot-and-mouth disease vaccine, Bol. Centr. Panam. Fiebre Aftosa, 39–40, 47

Gomes, 1984, Observations on the influence of colostral antibodies on the anameatic response of calves revaccinated against foot-and-mouth disease, Bol. Centr. Panam. Fiebre Aftosa, 49–50, 23

Gomes, I., 1979. Use of oil-adjuvant foot-and-mouth disease vaccine for the control of an outbreak in swine in the municipality of Campos, RJ, Brazil. PANAFTOSA MONTHLY REPORT 11(7), 82–84.

Gomes, 1980, Response of cattle to foot-and-mouth disease (FMD) virus exposure one year after inmunization with oil adjuvanted FMD vaccine, Bol. Centr. Panam. Fiebre Aftosa, 37–38, 31

Graves, 1968, Early response of cattle and swine to inactivated foot-and-mouth disease vaccine, Res. Vet. Sci., 9, 35, 10.1016/S0034-5288(18)34588-0

Graves, 1971, Contact transmission of foot-and-mouth disease from infected to susceptible cattle, J. Infect. Dis., 123, 386, 10.1093/infdis/123.4.386

Gurhan, 1993, Establishment of the prevalence of persistently infected cattle and sheep in Anatolia with FMDV, J. Etlik. Vet. Microbiol., 7, 52

Haas, B., Zerbini, I., Moos, A., Amadori, M., 2001. Diagnostic possibilities for the detection of carrier animals. EU workshop: pesrsistence of foot-and-mouth disease and the risk of carrier animals 28–29 June, 2001, ID-Lelystad, Lelystad, The Netherlands, pp. 1.

Hancock, 1993, Foot and mouth disease in a flock of sheep in southern Brazil, Vet. Rec., 132, 278, 10.1136/vr.132.11.278

Hedger, 1971, The carrier state in foot-and-mouth disease, and the probang test, State Vet. J. (UK), 26, 45

Hedger, 1970, Observations on the carrier state and related antibody titres during an outbreak of foot-and-mouth disease, J. Hyg. Camb., 68, 53, 10.1017/S0022172400028497

Hedger, 1972, Foot-and-mouth disease and the African buffalo (Syncerus caffer), J. Comp. Path., 82, 19, 10.1016/0021-9975(72)90022-9

Hedger, R.S. (1976). Foot and mouth disease in wildlife with particular reference to the African buffalo (Syncerus caffer). In: Andrew Page (Ed.), Wildlife Diseases. New York, Plenum, pp. 235–244.

Henderson, 1969, The outbreak of foot-and-mouth disease in Worcestershire. An epidemiological study, with special reference to spread of disease by wind carriage of the virus, J. Hyg. Camb., 67, 21, 10.1017/S0022172400041383

Hofmann, 2000, Rescue of infectious classical swine fever and foot-amd-mouth disease virus by RNA transfection and virus detection by RT-PCR after extended staorgage of samples in Trizol, J. Virol. Methods, 87, 29, 10.1016/S0166-0934(00)00154-3

Hugh-Jones, 1970, Studies on the 1967–1968 foot-and-mouth disease epidemic. The relation of weather to the spread of disease, J. Hyg. Camb., 68, 253, 10.1017/S0022172400028722

Hyslop, 1965, Air-borne infection with the virus of foot-and-mouth disease, J. Comp. Path., 75, 119, 10.1016/0021-9975(65)90002-2

Ilott, 1997, Dexamethasone inhibits virus production and the secretory IgA response in oesophageal-pharyngeal fluid in cattle persistently infected with foot-and-mouth disease virus, Epidemiol. Infect., 118, 181, 10.1017/S0950268896007376

Kaaden, O.R., Eissner, G., Dietschold, B., Böhm, 1972. Further studies on the FMD carrier state in Cattle, including investigations in the field. Rep. Sess. Res. Group Stand. Techn. Comm. Contr. FMD (FAO), Rome, pp 136–138.

Keeling, 2001, Dynamics of the 2001 UK foot and mouth epidemic: stochastic dispersal in a heterogeneous landscape, Science, 294, 813, 10.1126/science.1065973

King, 1981, Biochemical identification of viruses causing the 1981 outbreaks of foot-and-mouth disease in the UK, Nature, 293, 479, 10.1038/293479a0

Korn, 1957, Experimentelle Untersuchungen zum Virusnachweis im Inkubationsstadium der Maul-und Klauenseuche und ihrer Pathogenese, Arch. Exp. Vet. Med., 11, 637

Lee, 2000, Foot-and-mouth disease in the Republic of Korea in 2000, Bull. Off. Int. Epiz., 112, 306

Lee, J., 2000. Foot-and-mouth disease in the Republic of Korea: follow up Report No. 3. OIE Disease Information, 13(31), 121–122.

de Leeuw, 1978, Excretion of foot-and-mouth disease virus in oesophageal-pharyngeal fluid and milk of cattle after intranasal infection, J. Hyg., Camb., 81, 415, 10.1017/S0022172400025304

de Leeuw, 1979, Vaccination of pigs with formaldehyde inactivated aluminum hydroxide foot-and-mouth disease vaccines, potentiated with diethylaminoethyldextran (DEAE-D), Zbl. Vet. Med. B, 26, 85, 10.1111/j.1439-0450.1979.tb00797.x

Loeffler, 1897, Summarischer bericht über die ergebnisse untersuchungen zur erforschung der maul und klauenseuche, Zentbl. Bakt. Abi. Org., 22, 257

Löffler, 1898, Zentbl. Bakt. Abt. I Org., 28, 371

Lubroth, J., Yedloutschnig, R.J., 1987. Foot and mouth disease studies in the llama (Lama glama). Mexican-US Commission FMD, Culle Hegal 713, Colonia Polanco, 11560, Mexico. Proceedings of the United States Animal Health Association 91, 313–316.

MacKay, 1998, Antibody to the non-structural proteins of foot-and-mouth disease virus in vaccinated animals exposed to infection, Vet. Q., 20, 1, 10.1080/01652176.1998.9694950

Machado, M.A., Jr. 1969. Aftosa—A historical survey of foot-and-mouth disease and inter-american relations. State University of New York Press, Thurlow Terrace, Albany, NY 12201, 1969. Lib. Of Congress cat. Card # 69-11317.

Manocchio, 1974, Selective necrosis of the islets of Langerhans in a cow with experimental foot and mouth disease, Veterinaria, 50, 182

Martin, 1987

McKercher, 1967, Foot-and-mouth disease in swine: response to inactivated vaccines, Arch. Ges. Virusforsch, 22, 451, 10.1007/BF01242966

McKercher, 1969, Response of swine to inactivated foot-and-mouth disease vaccines. Duration of immunity and local tissue reactions, Arch. Ges. Virusforsch, 28, 165, 10.1007/BF01249381

McKercher, 1977, A review of the current status of oil adjuvants in foot-and-mouth disease vaccines, Develop. Biol. Stand., 35, 107

McVicar, 1976, Growth of foot-and-mouth disease virus in the upper respiratory tract of non-immunized, vaccinated, and recovered cattle after intranasal inoculation, J. Hyg. Camb., 76, 467, 10.1017/S0022172400055406

McVicar, 1977, The pathobiology of foot and mouth disease in cattle. A review, Bltn. Centr. Panam. Fiebre Aftosa, 26, 9

McVicar, 1977, The influence of infectious bovine rhino-tracheitis virus on the foot and mouth disease carrier state, US Anim. Health. Assoc. Proc., 80, 254

McVicar, 1968, Sheep and goats as foot-and-mouth disease carriers, Proc. US Livestock Sanit. Assoc., 72, 400

McVicar, 1970, Foot and mouth disease: the agar gel diffusion precipitation test for antibody to virus-infection associated (VIA) antigen as a tool for epizootiologic surveys, Am. J. Epidemiol., 92, 273, 10.1093/oxfordjournals.aje.a121207

McVicar, 1974, Neutralization activity in the serum and oesophageal-pharyngeal fluid of cattle after exposure to foot-and-mouth disease virus and subsequent re-exposure, Arch. Ges. Virusforsch, 44, 173, 10.1007/BF01250231

McVicar, J.W., Sutmoller, P. Ferris, D.H., Campbell, C.H., 1974. Foot and Mouth Disease in white-tailed deer: clinical signs and transmission in the laboratory. Proceedings of the 78th Annual Mgt USAnimal Health Association 1974.

Mettam, A.E., 1915. Foot-and-mouth disease. Proceedings of the 10th International Veterinary Congress, London 1914, pp. 105–133.

Mezencio, 1999, Evidence for the persistence of foot-and-mouth disease virus in pigs, Vet. J., 157, 213, 10.1053/tvjl.1999.0357

Michelsen, 1961, Experience with vaccination of pigs, Arch. Exp. Vet. Med., 15, 317

Molak, 1997, Toxic chemicals, non-cancer risk analysis and US institutional approaches to risk analysis, 16

Moss, 1998, Comparison of plaque tests and nested PCR for the detection of FMDV in nasal swabs and probang samples, J. Virol. Methods, 80, 59, 10.1016/S0166-0934(99)00031-2

Mowat, 1962, Growth of foot-and-mouth disease virus in a fibroblastic cell line derived from hamster kidneys, Nature, 194, 253, 10.1038/194253a0

Murphy, 1994, Analysis of sites of foot-and-mouth disease virus persistence in carrier cattle via the polymerase chain reaction, Arch. Virol., 136, 299, 10.1007/BF01321059

Office International des Epizooties (OIE) 1999. Foot and mouth disease. In: International animal health code: mammals, birds and bees, eigth ed. OIE, Paris, pp. 63–73.

Penberthy, 1901, Foot-and-mouth disease, J. Comp. Path. Ther., 14, 16, 10.1016/S0368-1742(01)80003-5

Plum Island Animal Disease Center; Pan American Foot-and-Mouth Disease Center, 1975. Foot-and-mouth disease vaccines. I. Comparison of vaccines prepared from virus inactivated with formalin and adsorbed an aluminum hydroxide gel with saponin and virus inactivated with acetylethyleneimine and emulsified with incomplete freund's adjuvant. Bol. Centr. Panam. Fiebre Aftosa, 19–20, 9–16.

Plum Island Animal Disease Center; Pan American Foot-and-Mouth Disease Center, 1975. Foot-and-mouth disease vaccines II. Studies on the duration of inumnity in catlle and pigs. Bol. Centr. Panam. Fiebre Aftosa, 19–20, 24–30.

Potel, 1958, Neue Ergebnisse auf dem Gebiet der experimentellen Pathologie de Maul-und Klauenseuche, Mh. Vet. Med., 13, 401

Röhrer, 1980, 247

Rosenberg, 1976, Prevalencia de anticuerpos contra el antı́geno asociado a la infeccı́on (VIA) de la fiebre aftosa en bovinos del Chaco Paraguayo, Bol. Centr. Panam. Fiebre Aftosa, 21–22, 1

Rosenberg, 1977, Susceptibilidad del carpicho o capibara (Hidrochoerus hidrochoeris) al viirus de la fiebre aftosa, Bol. Centr. Panam. Fiebre Aftosa, 27–28, 43

Rosenbusch, 1960, Efficacia comperativa de vacunas antiaftosa elaboradas con virus cultivado y epitelio lingeral bovine, Rev. Med. Vet. (Buenos Aires), 41, 155

Rubino, M.C., 1946. Sobre la Actual Epizootia de Fiebre Aftosa (1943) In: Compilacion de Trabajos Cientificos del Dr. Miguel C. Rubino. Ministerio de Ganaderia y Agricultura, R.O. del Uruguay, 1946, 355–366. ‘Impresora Uruguaya’, Montevideo.

Rubino, M.C., 1946. La Fiebre Aftosa, Estado Actual de los Conocimientos sobre su Profilaxis Biologica. In: Compilacion de Trabajos Cientificos del Dr. Miguel C. Rubino, Ministerio de Ganaderia y Agricultura, R.O. del Uruguay, 1946, 297–353. ‘Impresora Uruguaya’, Montevideo.

Rubino, M.C., 1946. La Fiebre Aftosa. In: Compilacion de Trabajos Cientificos del Dr. Miguel C. Rubino, Ministerio de Ganaderia y Agricultura, R.O del Uruguay, 1946, 282–295.'Impresora Uruguaya,’ Montevideo.

Salt, 1993, The carrier state in foot and mouth disease: an immunological review, Br. Vet. J., 149, 207, 10.1016/S0007-1935(05)80168-X

Salt, J.S., Williams, L., Statham, R., Barnett, P.V., 1995. Further Studies on the Rate of Development of Protection in Cattle Given Emergency Vaccination Against FMD. Rep. Session Res. Group Standing Techn. Comm. Eur. Comm. Contr. FMD, Moeldling, Denmark, FAO, Rome, Appendix 17,pp. 90–97.

Salt, J.S., Dani, P., Williams, L., Barnett, P., 1997. Efficacy Studies in Pigs with Two Novel Oil-adjuvanted ‘Emergency’ FMD Vaccines. Rep. Session Res. Group Standing Techn. Comm. Eur. Comm. Contr. FMD, Israel, Appendix 23, pp. 162–169.

Salt, 1998, Emergency vaccination of pigs against foot-and-mouth disease: protection against disease and reduction in contact transmission, Vaccine, 16, 746, 10.1016/S0264-410X(97)86180-4

Sarkisyan, 1973, Carriage of foot and mouth disease virus by animals that have recovered from the disease, Veterinariya (Moscow), 9, 46

Schmidt, 1938, Adsorbtion von Maul und Klauenseuchevirus an Aluminium-hydroxyd unter besonderer Besucksichtiging de immunisierenden Eigenschaften der Virusadsorbate, Z. Immun. Forsc., 92, 392

Scott, F.W., Cottral, G.E., Gailiunas, P., 1965. Presence of foot-and-mouth disease virus in the pituitary and central nervous system of experimentally infected cattle. Proceedings of the 69th Annual Mtg US Livestock Sanitary Assoc. p. 87, 1965.

Scott, 2001, Development of a chromatographic strip test for the pen-side detection of foot-and-mouth disease virus antigen, J. Vir. Methods, 96, 189, 10.1016/S0166-0934(01)00334-2

Seibold, 1963, A revised concept of the lingual lesions in cattle with foot-and-mouth disease, Am. J. Vet. Res., 24, 1123

Sellers, 1971, The effect of killing and removal of animals affected with foot-and-mouth disease on the amounts of airborne virus present in looseboxes, Br. Vet. J., 127, 358, 10.1016/S0007-1935(17)37440-7

Sellers, 1972, The effect of spaying on the amount of airborne foot-and-mouth disease virus present in loose-boxes, J. Hyg. Camb., 70, 551, 10.1017/S0022172400063130

Sellers, 1971, Quantitative aspects of the spread of foot and mouth disease, Vet. Bull., 41, 431

Sellers, R.F., Herniman, K.A.J., Mann, J.A., 1971. Transfer of foot-and-mouth disease virus in the nose of man from infected to non-infected animals. Vet. Rec. 16 October, 447–449.

Sellers, 1970, Inhalation, persistence and dispersal of foot-and-mouth disease virus by man, J. Hyg. Camb., 70, 551, 10.1017/S0022172400063130

Sellers, 1973, The Hampshire epidemic of foot-and-mouth disease, J. Hyg. Camb., 71, 15, 10.1017/S0022172400046179

Sellers, 1969, Air-borne excretion of foot-and-mouth disease virus in monolayer cultures of calf thyroid cells, Nature(Lond.), 210, 1079

Sharma, 1978, Studies on foot and mouth disease in sheep with special reference to distribution of the virus and carrier status, Vet. Res. Bull., 1, 156

Singh, 1979, Studies on foot-and-mouth disease in goats with special reference on the distribution of the virus and carrier status, Vet. Res. Bull., 2, 93

Skinner, 1964, Environmental factors influencing the response of guinea pigs to modified strains of foot-and-mouth disease virus, Bull. Off. Int. Epiz., 61, 1523

Snowdon, 1966, Growth of foot-and-mouth disease virus in monolayer cultures of calf-thyroid cells, Nature, London, 210, 1079, 10.1038/2101079a0

Sørensen, J.H., 2000. Rep. Res. Gr. Meeting Eur. Comm. Contr. FMD, Brovich, FAO, Rome, 1999.

Sørensen, 2001, Modelling the atmospheric dispersion of foot-and-mouth disease for emergency preparedness, Phys. Chem. Earth, B26, 93, 10.1016/S1464-1909(00)00223-9

Sørensen, 2000, An integrated model to predict the atmospheric spread of foot-and-mouth disease virus, Epid. Infect., 124, 577, 10.1017/S095026889900401X

Sugiura, 2001, Eradication of foot and mouth disease in Japan, Rev. Sci. Off. Int. Epiz., 20, 701, 10.20506/rst.20.3.1301

Sutmoller, 1972, The epizootiological importance of foot-and-mouth carriers. III. Exposure of pigs to bovine carriers, Arch. Ges. Virusforsch, 37, 78, 10.1007/BF01241153

Sutmoller, 1976, Pathogenesis of foot-and-mouth disease: the lung as an additional portal of entry of the virus, J. Hyg. (Camb.), 77, 235, 10.1017/S0022172400024669

Sutmoller, 1981, Pathogenesis of foot-and-mouth disease: The lung as an additional and simulated natural foot-and-mouth disease infection in cattle, J. Comp. Path., 91, 599, 10.1016/0021-9975(81)90089-X

Sutmoller, 1997, Contamination od animal products: the minimum pathogen dose required to initiate infection, Rev. Sci. Tech. Off. Int. Epiz., 16, 30, 10.20506/rst.16.1.996

Sutmoller, 2001, Verdenking van MKZ onder Nederlands wild, Tijdschr. Diergeneesk., 126, 434

Sutmoller, 1965, Foot-and-mouth disease carriers, Vet. Rec., 77, 968, 10.1136/vr.77.33.968

Sutmoller, 1967, A review of the carrier state in foot-and-mouth disease, US Livestock Sanit. Assoc. Proc., 71, 386

Sutmoller, 1968, The epizootiological importance of foot-and-mouth disease carriers. I. Experimentally produced foot-and-mouth disease carriers in susceptible and immune cattle, Arch. Ges. Virusforsch, 23, 227, 10.1007/BF01241895

Sutmoller, 1967, Improved techniques for the detection of foot-and-mouth disease virus in carrier cattle, Arch. Ges. Virusforsch, 21, 170, 10.1007/BF01241441

Swam, H., Davidson, F., Anemaet, D.A.J., Barteling, S.J., 1994. New Strategies for Control of Foot-and-Mouth Disease (FMD) Outbreaks in unvaccinated Europe: use of a higly potent Vaccine on infected Pig Farms as an alternative to ‘stamping out’? Rep. Session Res. Group Standing Techn. Comm. Eur. Comm. Contr. FMD, Vienna, Austria. FAO Rome.

Telling, 1965, Submerged cultures of hamster kidney cells in a stainless steel vessel, Biotechnol. Bioeng., 7, 417, 10.1002/bit.260070309

Thiermann, 1997, The relationship between the World Trade Organisation and the Office International de Epizooties, Rev. Sci. Tech. Off. Int. Epiz., 16, 13, 10.20506/rst.16.1.998

Thomson, 1994, Foot and mouth disease, 825

Thomson, 1995, Overview of FMD in Southern Africa. Revue Scientifique et Technique, Off. Int. Epiz., 14, 503, 10.20506/rst.14.3.855

Thomson, G.R., 1996. The role of carriers animals in the transmission of foot and mouth disease. Off. Int. Epiz., 64th General Session, Paris, 20–24 May, 1996, pp. 87–103.

Tinline, 1970, Lee wave hypothesis for the initial pattern of spread during the 1967–68 foot-and-mouth epizootie, Nature(Lond.), 227, 860, 10.1038/227860b0

Tosh, 1997, One-tube and one-buffer system of RT-PCR amplification of 1D gene of foot-and-mouth disease virus field isolates, Acta Virologia, 41, 153

Trautwein, 1927, Die pluralität des maul-und-klauenseuche virus, Arch. Wiss. Prakt. Tierheilk., 56, 505

Ubertini, 1968, Controlli di efficacia su bovini di vaccini antiaftosi monovalenti e trivalenti preparati con virus da cellule BHK, Atti Della Societa Italiana Delle Scienze Veterinarie, XXII, 895

Vallée, 1922, Sur la pluralité du virus aphteux, Comp. Rend. Acad. Sci., 174, 1498

Vallée, 1925, Sur la pluralité du virus aphteux, Comp. Rend. Acad. Sci., 174, 1498

Vallée, 1926, Immunisation against foot-and-mouth disease by formolised virus, Rev. Gen. Med. Vet., 35, 129

Vosloo, 1992, Genetic relationships between South African SAT-2 isolates of foot and mouth virus, Epidemiol. Infect., 109, 547, 10.1017/S0950268800050536

Waldmann, 1937, Die aktive Immunisierung des Rindes gegen Maul-und Klausenseuche, Zbl. Bakt. I. Orig., 138, 401

Waldmann, 1926, Experimentelle untersuchen über die pluralität des maul-und-klauenseuche virus, Berl. Tierärtzl. Wschr., 42, 569

Waldmann, 1941, Die Entwicklung des Riemser Adsorbatimpfstoffes gegen Maul-und Klauenseuche und seine Herstellung, Zbl. Bakt. I. Orig., 148, 1

Wittmann, 1970, Die Verwendung von Diethylamino-aethyl-Dextran (DEAE-D) als Adjuvans bei der Immunisierung von Meerschweinchen mit inaktivierten Maul-und-Klauenseuche (MKS)-Viren, Zbl. Bakt. I. Orig., 213, 1

Wittmann, 1972, Versuche zur Revakzinierung von Schweinen mit einer Athylathylenimin (EEI)/DEAE-Dextran-Vakzine gegen Maul-und-Klauenseuche, Zbl. Vet. Med. B, 19, 45, 10.1111/j.1439-0450.1972.tb00369.x

Woolhouse, 2001, Foot-and-mouth disease under control in the UK, Nature, 411, 258, 10.1038/35077149