Contributions of basic science to understanding addiction

Agrawal, A. and Lynskey, M.T. (2008) Are there genetic influences on addiction: Evidence from family, adoption and twin studies. Addiction 103: 1069–1081.

Anthony, J.C., Warner, L. and Kessler, R.C. (1994) Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey. Experimental and Clinical Psychopharmacology 2: 244–268.

Barr, A.M. and Markou, A. (2005) Psychostimulant withdrawal as an inducing condition in animal models of depression. Neuroscience and Biobehavioral Reviews 29: 675–706.

Bechara, A. (2005) Decision making, impulse control and loss of willpower to resist drugs: A neurocognitive perspective. Nature Neuroscience 8: 1458–1463.

Belknap, J.K., Metten, P., Beckley, E.H. and Crabbe, J.C. (2008) Multivariate analyses reveal common and drug-specific genetic influences on responses to four drugs of abuse. Trends in Pharmacological Sciences 29: 537–543.

Beveridge, T.J., Gill, K.E., Hanlon, C.A. and Porrino, L.J. (2008) Parallel studies of cocaine-related neural and cognitive impairment in humans and monkeys. Philosophical Transactions of the Royal Society of London Series B Biological Sciences 363: 3257–3266.

Bocher, M. et al (2001) Cerebral activation associated with sexual arousal in response to a pornographic clip: A 15O-H2O PET study in heterosexual men. Neuroimage 14: 105–117.

Bonci, A., Bernardi, G., Grillner, P. and Mercuri, N.B. (2003) The dopamine-containing neuron: Maestro or simple musician in the orchestra of addiction? Trends in Pharmacological Sciences 24: 172–177.

Carroll, F.I., Howard, J.L., Howell, L.L., Fox, B.S. and Kuhar, M.J. (2006) Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse. AAPS Journal 8: E196–E203.

Dew, B., Elifson, K. and Dozier, M. (2007) Social and environmental factors and their influence on drug use vulnerability and resiliency in rural populations. Journal of Rural Health 13 (Suppl): 16–21.

Dominguez, J.M. and Hull, E.M. (2005) Dopamine, the medial preoptic area, and male sexual behavior. Physiology & Behavior 86: 356–368.

Graham, A.W., Schultz, M.D.F., Mayo-Smith, M.F., Ries, R.K. and Wilford, B.B. (2003) Principles of Addiction Medicine, 3rd edn. Chevy Chase, MD: American Society of Addiction Medicine.

Jamner, L.D. et al (2003) Tobacco use across the formative years: A road map to developmental vulnerabilities. Nicotine and Tobacco Research 5 (1): S71–S87.

Joslyn, G. et al (2008) Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans. Proceedings of the National Academy of Science USA 105: 20368–20373.

Kendler, K.S., Karkowski, L.M., Corey, L.A., Prescott, C.A. and Neale, M.C. (1999) Genetic and environmental risk factors in the aetiology of illicit drug initiation and subsequent misuse in women. British Journal of Psychiatry 175: 351–356.

Kuhar, M.J., Ritz, M.C. and Boja, J.W. (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends in Neuroscience 14: 299–302.

Kuhar, M.I. (2002) Social rank and vulnerability to drug abuse. Nature Neurosci 5: 88–90.

Malin, D.H. and Goyarzu, P. (2009) Rodent models of nicotine withdrawal syndrome. Handbook of Experimental Pharmacology 192: 401–434.

Meaney, M.J., Brake, W. and Gratton, A. (2002) Environmental regulation of the development of mesolimbic dopamine systems: A neurobiological mechanism for vulnerability to drug abuse? Psychoneuroendocrinology 27: 127–138.

Morgan, D. et al (2002) Social dominance in monkeys' dopamine D2 receptors and cocaine self-administration. Nature Neuroscience 5: 169–174.

Nader, M.A. and Czoty, P.W. (2005) PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: Genetic predisposition versus environmental modulation. American Journal of Psychiatry 162: 1473–1482.

Nestler, E.J., Hyman, S.E. and Malenka, R.C. (2001) Molecular Neuropharmacology: A Foundation for Clinical Neuroscience. New York: McGraw-Hill.

Palmiter, R.D. (2007) Is dopamine a physiologically relevant mediator of feeding behavior? Trends in Neuroscience 30: 375–381.

Pettit, H.O. and Justice Jr, J.B. (1991) Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. Brain Research 539: 94–102.

Redish, A.D., Jensen, S. and Johnson, A. (2008) A unified framework for addiction: Vulnerabilities in the decision process. Behavioral and Brain Sciences 31: 415–437.

Schierenbeck, T., Riemann, D., Berger, M. and Hornyak, M. (2008) Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana. Sleep Medicine Reviews 12: 381–389.

Siegel, G.J., Agranoff, B.W., Albers, W.R., Fisher, S.K. and Uhler, M.D. (1999) Basic Neurochemistry, Sixth edn, Lippincott-Raven, New York, NY.

Spiga, S., Lintas, A. and Diana, M. (2008) Addiction and cognitive functions. Annals of the New York Academy of Sciences 1139: 299–306.

Uhl, G.R. et al (2008) Molecular genetics of addiction and related heritable phenotypes: Genome-wide association approaches identify ‘connectivity constellation’ and drug target genes with pleiotropic effects. Annals of the New York Academy of Sciences 1141: 318–381.

Volkow, N.D. et al (1993) Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 14: 169–177.

Volkow, N.D., Wang, G.J., Fowler, J.S. and Telang, F. (2008) Overlapping neuronal circuits in addiction and obesity: Evidence of systems pathology. Philosophical Transactions of the Royal Society of London Series B Biological Sciences 363: 3191–3200.

Wagner, F.A. and Anthony, J.C. (2007) Male-female differences in the risk of progression from first use to dependence upon cannabis, cocaine and alcohol. Drug and Alcohol Dependence 86: 191–198.

White, N.M. (1986) Control of sensorimotor function by dopaminergic nigrostriatal neurons: Influence on eating and drinking. Neuroscience and Biobehavioral Reviews 10: 15–36.

Wise, R.A. (2005) Forebrain substrates of reward and motivation. Journal of Comparative Neurology 493: 115–121.

Woolverton, W.L. and Schuster, C.R. (1983) Behavioral and pharmacological aspects of opioid dependence: Mixed agonist-antagonists. Pharmacological Reviews 35: 33–52.