Contributions of Epidemiology to Our Understanding of Migraine

Headache - Tập 53 Số 2 - Trang 230-246 - 2013
Kathleen R. Merikangas1
1Genetic Epidemiology Research Branch,National Institute of Mental Health,Bethesda, MD,USA.

Tóm tắt

BackgroundDuring the past decade, the introduction of the second edition of the International Classification of Headache Disorders (ICHD‐II) and the initiation of active campaigns to increase awareness of the high magnitude, burden, and impact of migraine have stimulated numerous studies of population‐based data on the prevalence, correlates, and impact of migraine.ObjectiveThis paper provides an update of the literature on the worldwide epidemiology of migraine from studies that included the ICHD‐II criteria. The aims of this paper are: (1) to review evidence regarding the magnitude of migraine; (2) to summarize information on the correlates and impact of migraine; and (3) to discuss the contributions, challenges, and future directions in the epidemiology of migraine. Evidence on the magnitude of migraine is divided into the following types of data: (1) prevalence rates of ICHD‐II‐defined migraine and tension‐type headache from international population‐based studies of adults; (2) the magnitude of migraine in U.S. studies; (3) ICHD‐II‐based international prevalence rates of ICHD‐II‐defined migraine in children; and (4) incidence rates of migraine from prospective longitudinal studies.MethodsA comprehensive review of the literature on the prevalence of migraine subtypes and tension‐type headache defined by ICHD‐II criteria during the past decade was conducted and aggregate weighted rates across studies were derived.ResultsAcross the 19 studies of adults that employed the ICHD‐II criteria, the aggregate weighted estimates of the 12‐month prevalence of definite migraine are 11.5%, and probable migraine of 7%, yielding a total of 18.5%. The cross‐study weighted aggregate rate of migraine with aura is 4.4%, chronic migraine is 0.5%, and of tension‐type headache is 13%. There has been even greater growth in international prevalence data on migraine in children, with a total of 21 studies of children that have employed the ICDH‐II criteria. The aggregate weighted rate of definite migraine in children is 10.1% and migraine with aura is 1.6%. The well‐established demographic correlates of migraine including the equal sex ratio in childhood, with increasing prevalence of migraine in females across adolescence to mid‐adulthood were confirmed in these studies. Despite increasing effort to increase awareness of migraine, approximately 50% of those with frequent and/or severe migraine do not receive professional treatment.ConclusionsThis review demonstrates that the descriptive epidemiology of migraine has reached its maturity. The prevalence rates and sociodemographic correlates have been stable across 50 years. These developments justify a shift in efforts to the application of the designs and methods of analytic epidemiology. Retrospective case–control studies followed by prospective cohort studies that test specific associations are likely to enhance our understanding of the predictors of incidence and progression of migraine, subtypes of migraine with differential patterns of onset and course, and specific environmental exposures that may have either causal or provocative influences on migraine etiology.

Từ khóa


Tài liệu tham khảo

10.1136/jnnp.38.6.613

10.1093/oxfordjournals.epirev.a036268

10.1111/j.1468-2982.2007.01288.x

Lipton RB, 2005, The epidemiology of migraine, Am J Med, 118, 3S

10.1111/j.1526-4610.2007.00671.x

10.1016/S1474-4422(08)70062-0

10.1007/s10194-008-0038-6

10.1016/j.ncl.2008.11.011

10.1111/j.1526-4610.2009.001460.x

10.1007/s10194-009-0173-8

10.1007/s11916-010-0146-2

10.1111/j.1468-2982.2009.01941.x

10.1007/s10194-010-0217-0

10.1111/j.1469-8749.2010.03793.x

10.1007/s11916-010-0157-z

Manzoni GC, 2011, Epidemiology of headache, Handb Clin Neurol, 97, 1

1988, Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Headache Classification Committee of the International Headache Society, Cephalalgia, 8, 1

2004, International classification of headache disorders‐II, Cephalalgia, 24, 1

10.1111/j.1526-4610.2012.02259.x

10.1111/j.1468-2982.2009.01994.x

10.3988/jcn.2012.8.3.204

10.1111/j.1526-4610.2011.02061.x

10.1177/0333102412438977

10.1007/s10194-011-0414-5

10.1177/0333102411434811

10.1177/0333102410391488

10.1177/0333102410382794

10.1136/bmj.d5076

10.1111/j.1468-2982.2008.01699.x

10.1159/000310940

10.1007/s10194-012-0425-x

10.1212/WNL.0b013e3181c34abb

10.1111/j.1468-2982.2005.00977.x

10.1007/s10072-012-1200-0

10.1212/01.wnl.0000252808.97649.21

10.1111/j.1468-2982.2008.01782.x

10.1111/j.1526-4610.2012.02090.x

10.1177/0333102412439799

10.1046/j.1468-2982.2003.00568.x

10.1007/s10194-011-0342-4

10.1007/s10194-010-0264-6

10.1007/s10194-005-0252-4

10.1007/s10194-005-0241-7

10.1007/s10194-005-0202-1

10.1016/S1474-4422(04)00703-3

10.1007/s11916-012-0296-5

10.1001/jama.1992.03480010072027

10.1046/j.1526-4610.2001.041007646.x

10.1212/01.wnl.0000297192.84581.21

10.1016/j.jpeds.2012.01.040

10.1097/00002826-199201001-00145

10.1001/archpsyc.57.10.945

10.1177/0333102409355601

10.1097/PSY.0b013e31817f9e80

10.1177/0883073808327831

10.1177/0333102410390395

10.1001/archpediatrics.2010.17

10.1212/WNL.0b013e318271f812

10.1016/j.jocn.2012.02.020

10.1542/peds.2005-2274

10.1111/j.1468-2982.2007.01289.x

10.1111/j.1468-2982.2007.01319.x

10.1111/j.1468-2982.2008.01812.x

10.1111/j.1526-4610.2009.01605.x

10.1111/j.1526-4610.2006.00437.x

10.1016/j.braindev.2007.01.003

10.1111/j.1526-4610.2011.02001.x

10.1111/j.1526-4610.2010.01776.x

10.1177/0333102409356327

10.1111/j.1468-2982.2004.00681.x

10.1177/0883073807306264

10.1111/j.1468-2982.2007.01343.x

10.1177/0333102409355837

10.1016/j.pediatrneurol.2006.11.006

10.1111/j.1526-4610.2006.00362.x

10.1111/j.1442-200X.2007.02484.x

10.1212/01.wnl.0000265212.90735.64

10.1111/j.1526-4610.2011.02085.x

10.1111/j.1468-2982.2005.00954.x

10.1111/j.1468-2982.2007.01277.x

10.1046/j.1468-2982.1992.1202085.x

10.1212/01.wnl.0000172918.74999.8a

10.1046/j.1468-2982.1997.1704488.x

10.1212/WNL.42.9.1657

10.1093/oxfordjournals.aje.a116014

10.1002/sim.3831

10.1111/j.1468-2982.2008.01666.x

10.1111/j.1468-2982.1998.1807449.x

10.1111/j.1468-2982.2006.01108.x

10.1111/j.1468-2982.2000.00090.x

10.1046/j.1468-2982.2002.00337.x

10.1046/j.1526-4610.2003.03047.x

10.1038/ng.2307

10.1038/ng.652

10.1038/ng.856

10.1007/s10194-011-0321-9

10.1016/0021-9681(70)90054-8

10.1017/S1092852900018745

10.1097/01.wco.0000169750.52406.a2

10.1177/0333102410373159

10.1046/j.1526-4610.2000.00071.x

10.1046/j.1468-2982.2000.00085.x

10.1038/oby.2007.32

10.1001/archneur.1997.00550160012009

10.1038/nrneurol.2010.14

10.1177/0333102498018S2210

10.1016/S0733-8619(05)70298-X

10.1111/j.1526-4610.2011.02036.x

10.1212/WNL.0b013e31826c1b7b

10.1136/bmj.322.7295.1145

10.1016/0022-3956(88)90076-3

10.1111/j.1526-4610.2010.01705.x

Lipton RB, 2012, Barriers to the diagnosis and treatment of migraine: Effects of sex, income, and headache features, Headache

10.1542/peds.112.1.e1

10.1016/j.euroneuro.2011.08.008

10.1016/j.yebeh.2011.12.012

10.1111/j.1526-4610.2008.01217.x

10.1111/j.1468-1331.2011.03612.x

10.1111/j.1468-2982.2007.01397.x

10.1111/j.1526-4610.2007.00990.x

10.1097/JOM.0b013e31803b9510

10.1177/0333102411425960

10.1097/JOM.0b013e31822cff3c

10.1111/j.1526-4610.2006.00631.x

Thông tin
Thông tin xuất bản

Headache

Tập 53 Số 2

230-246

Thông tin tác giả