Concurrent Infantile Hemangioendothelioma and Mesenchymal Hamartoma in a Developmentally Arrested Liver of an Infant Requiring Hepatic Transplantation

SAGE Publications - Tập 6 - Trang 552-557 - 2003
Pablo A. Bejarano1, Maria F. Serrano1, Javier Casillas2, Louis P. Dehner3, Tomoaki Kato4, Naveen Mittal5, Maria M. Rodriguez1, Andreas Tzakis4
1Department of Pathology, University of Miami School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz Center—Room 2042, Miami, FL 33136, USA
2Department of Radiology, University of Miami School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136, USA
3Department of Pathology, Washington University Medical Center, One Barnes Hospital Plaza, St. Louis, MO 63110, USA
4Department of Surgery, University of Miami School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136, USA
5Department of Pediatrics, University of Miami School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136A, USA

Tóm tắt

A newborn female underwent a surgical resection for a hepatic mass discovered prenatally by ultrasonography, and diagnosed pathologically as a mesenchymal hamartoma. Within 4 months after surgery, multiple cutaneous hemangiomas developed and a multinodular mass was detected in the liver. A liver biopsy showed an infantile hemangioendothelioma with type I features. An orthotopic liver transplant was performed due to the extensive nature of the hepatic involvement and progressive respiratory compromise. Virtually the entire liver was involved by a large infantile hemangioendothelioma. A multicystic mesenchymal hamartoma was also found on the left side. In addition, the uninvolved hepatic parenchyma had features recapitulating the fetal liver. This simultaneous involvement of the liver by a mesenchymal hamartoma and infantile hemangioendothelioma is unique. A review of the literature revealed only one incompletely characterized case with similar findings.

Tài liệu tham khảo

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SAGE Publications

Tập 6

552-557

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