Conceptos generales sobre el metabolismo del hierro

Andrews, 1999, Disorders of iron metabolism, NEJM, 341, 1986, 10.1056/NEJM199912233412607 Hallberg, 1986, Effect of ascorbic acid on iron absortion from differents types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in differnt amounts in differents meals, Hum Nutr Apll Nutr, 40, 97 Conrad, 1993, A concise review: Iron absortion -the mucin- mobilferrin-integrin pathway. A competitive pathway for metal absortion, Am J Hematol, 42, 67, 10.1002/ajh.2830420114 Gunshin, 1997, Cloning and characterization of a mammalian proton-coupled metal-ion transporter, Nature, 388, 482, 10.1038/41343 Cannone-Hergaux, 1999, Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron, Blood, 93, 4406, 10.1182/blood.V93.12.4406 Riedel, 1995, Characterization and partial purification of a ferrireductase from human duodenal nicrovillus membranes, Biochem J, 309, 745, 10.1042/bj3090745 Umbreit, 1998, Iron absortion and cellular transport: The mobilferrin/paraferritin paradigm, Sem Hematol, 35, 13 Vulpe, 1999, Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse, Nat Genet, 21, 195, 10.1038/5979 Andrews, 1998, Iron is hot: An update on the pathophysiology of hemochromatosis, Blood, 92, 1845, 10.1182/blood.V92.6.1845 Parkkila, 1997, Immunochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract, Proc Natl Acad Sci USA, 94, 2534, 10.1073/pnas.94.6.2534 Lebron, 1998, Crystal structure of hemochromatosis protein HFE and characterization of its interaction with transferrin receptor, Cell, 93, 111, 10.1016/S0092-8674(00)81151-4 Feder, 1998, The hemochromatosis gene product complexes with transferrin receptor and lowers its affinity for ligand binding, Proc Natl Acad Sci USA, 95, 1472, 10.1073/pnas.95.4.1472 Zoller, 1999, Duodenal metal transporter (DMT-1, NRAMP-2) expression in patients with hereditary hemochromatosis, Lancet, 353, 2120, 10.1016/S0140-6736(98)11179-0 Finch, 1994, Regulators of iron balance in humans, Blood, 84, 1697, 10.1182/blood.V84.6.1697.1697 Conrad, 1995, Paraferritin: A large protein complex involved in inrganic iron transport contains integrin, mobilferrin and a flavin monooxytgenase with ferroreductase activity, Blood, 86, 1651 Worwood, 1989, Overview of iron metabolism at a mollecular level, J Intern Med, 226, 381, 10.1111/j.1365-2796.1989.tb01412.x Finch, 1986, Plasma ferritin determination as a diagnostic tool, West J Med, 145, 657 Brittenham, 1995, Disorders of iron metabolism: Iron deficiency and overload Ponka, 1998, Function and regulation of transferrin and ferritin, Sem Hematol, 35, 35 Theil, 1993, The IRE (iron regulatory element) family: Structures which regulate RNAm translation or stability, Biofactors, 4, 87 Lash, 1995, Iron metabolism and its regulation. A review, Ann Clin Lab Sci, 25, 20 Dix, 1992, The iron regulatory region of ferritin RNA is also a positive control element for iron-dependent translation, Biochemistry, 31, 2818, 10.1021/bi00125a024 Hartman, 1996, Microcytic anemia with iron malabsortion: an inherited disorder of iron metabolism, Am J Hematol, 51, 269, 10.1002/(SICI)1096-8652(199604)51:4<269::AID-AJH4>3.0.CO;2-U 1999, Iron fortification of infant formulas, Pediatrics, 104, 119, 10.1542/peds.104.1.119 Moyo, 1998, Evidence of genetic transmission in African iron overload, Blood, 91, 1076 Ferguson, 1992, Serum transferrin receptor distinguishes the anemia of chronic disease from iron deficiency anemia, J Lab Clin Med, 119, 385 Jurado, 1997, Iron, infections and anemia of inflammation, Clin Infect Dis, 25, 888, 10.1086/515549