Computed tomography (CT) findings in schizophrenia: Speculation on the meaning of it all

Journal of Psychiatric Research - Tập 18 - Trang 477-490 - 1984
Daniel R. Weinberger1
1Clinical Neuropsychiatry and Neurobehavior Section, Intramural Research Program, National Institute of Mental Health, Saint Elizabeth's Hospital, Washington, DC 20032, U.S.A.

Tài liệu tham khảo

Andreasan, 1982, Vetricular enlargement in schizophrenia: relationship to positive and negative symptoms, Am. J. Psychiat., 139, 297, 10.1176/ajp.139.3.297 Andreasan, 1982, Ventricular enlargement in schizophrenia: definition and prevalence, Am. J. Psychiat., 139, 292, 10.1176/ajp.139.3.292 Benes, 1982, Normal ventricles in young schizophrenics, Br. J. Psychiat., 141, 90, 10.1192/bjp.141.1.90 Buchsbaum, 1982, Cerebral glucography with positron tomography, Archs gen. Psychiat., 39, 251, 10.1001/archpsyc.1982.04290030001001 Crow, 1980, Molecular pathology of schizophrenia: more than one disease process, Br. med. J., 28, 66, 10.1136/bmj.280.6207.66 Davidson, 1969, Schizophrenia-like psychoses associated with organist disorders, Br. J. Psychiat., 113 Dewan, 1983, Central morphology in chronic schizophrenic patients, Biol. Psychiat., 118, 1133 Dewan, 1983, Cerebellar morphology in chronic schizophrenic patients: a controlled computed tomography study, Psychiat. Res., 10, 97, 10.1016/0165-1781(83)90108-7 Donnelly, 1980, Cognitive impairment associated with morphological brain abnormalities on computed tomography in chronic schizophrenic patients, J. nerv. ment. Dis., 168, 305, 10.1097/00005053-198005000-00011 Fish, 1977, Neurobiologic antecedents of schizophrenia in childhood, Archs gen. Psychiat., 34, 1297, 10.1001/archpsyc.1977.01770230039002 Fusher, J. The Prefrontal Cortex. Raven Press, New York. Golden, 1980, Cerebral ventricular size and neuropsychological impairment in young chronic schizophrenics, Archs gen. Psychiat., 37, 619, 10.1001/archpsyc.1980.01780190017001 Haug, 1962, Pneumoencephalographic studies in mental disease, Acta psychiat. scand., 38, 1 Heath, 1979, Gross pathology of the cerebellum in patients diagnosed and treated as functional psychiatric disorders, J. nerv. ment. Dis., 167, 585, 10.1097/00005053-197910000-00001 Ingvar, 1980, Abnormal distribution of cerebral activity in chronic schizophrenia: a neurophysiological interpretation, 107 Isaacson, 1982 Jernigan, 1982, Computer tomography in schizophrenics and normal volunteers, Archs gen. Psychiat., 39, 765, 10.1001/archpsyc.1982.04290070001001 Jernigan, 1982, CT measures of cerebrospinal fluid volume in alcoholics and normal volunteers, Psychiat. Res., 7, 9, 10.1016/0165-1781(82)90048-8 Jeste, 1983, Apmorphine response and subtyping of schizophrenia, Prog. Neuropsychopharmac, 7, 83, 10.1016/0278-5846(83)90092-1 Johnstone, 1976, Cerebral ventricular size and cognitive impairment in chronic schizophrenia, Lancet, ii, 924, 10.1016/S0140-6736(76)90890-4 Johnstone, 1978, The dementia of dementia praecox, Acta psychiat. Scand., 57, 305, 10.1111/j.1600-0447.1978.tb06899.x Johnstone, 1981, A CT study of 188 patients with schizophrenia, affective psychosis and neurotic illness, 237 Kellner, 1983, Relationship of cortisol hypersecretion to brain CT scan alterations in depressed patients, Psychiat. Res., 8, 191, 10.1016/0165-1781(83)90062-8 Kleinman, J.E., Karson, C.N., Weinberger, D.R., Freed, W.J., Bigelow, L.B. and Wyatt, R.J. (in press) Eyeblinking in chronic schizophrenic patients grouped by ventricular size. Am. J. Psychiat. Kleinman, 1982, Relationship between plasma prolactin concentrations and psychopathology in chronic schizophrenia, Archs gen. Psychiat., 39, 655, 10.1001/archpsyc.1982.04290060017004 Lee, 1980, Elevation of brain neuroleptic/dopamine receptors in schizophrenia, Am. J. Psychiat., 137, 191, 10.1176/ajp.137.2.191 Lippman, 1982, Cerebellar vermis dimensions on computerized tomographic scans of schizophrenic or bi-polar patients, Am. J. Psychiat., 139, 667, 10.1176/ajp.139.5.667 Luchins, 1983, Lateral ventricular size and drug-induced Parkinsonism, Psychiat. Res., 9, 9, 10.1016/0165-1781(83)90083-5 Mellanby, 1982, Effects of acute dehydration on computerized tomographic assessment of cerebral density and ventricular volume, Lancet, ii, 874, 10.1016/S0140-6736(82)90833-9 Mundt, 1980, Computertomographische Untersuchungen der Liquorraume an chronisch schizophrenen Patienten, Nervenarzt, 51, 743 Nasrallah, 1981, Cerebellar atrophy in schizophrenia and mania, Lancet, i, 1102, 10.1016/S0140-6736(81)92266-2 Nasrallah, 1982, Cerebral ventricular enlargement in subtypes of chronic schizophrenia, Archs gen. Psychiat, 319, 774, 10.1001/archpsyc.1982.04290070010003 Nasrallah, 1982, Cortical atrophy in schizophrenia and mania: a comparative CT study, J. clin. Psychiat., 43, 439 Nieto, 1972, Major psychoses, 2654 Nyback, 1982, Computed tomography of the brain in patients with acute psychosis and in healthy volunteers, Acta psychiat. scand., 65, 403, 10.1111/j.1600-0447.1982.tb00864.x Okasha, 1982, Cortical and central atrophy in chronic schizophrenia. A controlled study, Acta psychiat. scand., 65, 29, 10.1111/j.1600-0447.1982.tb00818.x Pearlson, 1981, Computerized tomographic scan changes in manic-depressive illness, Lancet, ii, 470, 10.1016/S0140-6736(81)90798-4 Potkin, 1983, Low CSF 5-hydroxyindoleacetic acid in schizophrenic patients with enlarged cerebral ventricles, Am. J. Psychiat., 140, 21, 10.1176/ajp.140.1.21 Reveley, 1982, Cerebral ventricular size in twins discordance for schizophrenia, Lancet, i, 540, 10.1016/S0140-6736(82)92047-5 Rieder, 1981, CAT scans in schizophrenia and affective disorders Schulsinger, 1984, CT scans in the Danish high risk schizophrenic project, Archs gen. Psychiat., 41, 602, 10.1001/archpsyc.1984.01790170076008 Schultz, 1983, Ventricular enlargement in teenage schizophrenic patients, Am. J. Psychiat., 140, 1592, 10.1176/ajp.140.12.1592 Schultz, 1982, Treatment response and ventricular brain ratio in young schizophrenic patients Smith, 1982, CAT scans and clinical response Snyder, 1982, Schizophrenia, Lancet, ii, 970, 10.1016/S0140-6736(82)90167-2 Standish-Barry, 1982, Pneumo-encephalographic and computerized axial tomographic scan changes in affective disorder, Br. J. Psychiat., 141, 614, 10.1192/bjp.141.6.614 Stevens, 1973, An anatomy of schizophrenia, Archs gen. Psychiat., 29, 177, 10.1001/archpsyc.1973.04200020023003 Stevens, 1982, Neuropathology of schizophrenia, Archs gen. Psychiat., 39, 1131, 10.1001/archpsyc.1982.04290100011003 Takahashi, 1981, CT scanning and the investigation of schizophrenia, 259 Tanaka, 1981, Computerized tomogaphy of the brain in schizophrenic patients, Acta Psychiat. Scand., 63, 191, 10.1111/j.1600-0447.1981.tb00667.x Targum, 1983, Cerebral ventricular size in major depressive disorder: Association with delusional symptoms, Biol. Psychiat., 18, 329 Torrey, 1974, Schizophrenia and the limbic system, Lancet, ii, 942, 10.1016/S0140-6736(74)91143-X van Kammen, 1983, Dopamine β hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy, Science, 220, 974, 10.1126/science.6133351 Weinberger, 1980, Cerebral ventricular enlargement in chronic schizophrenia: association with poor response to treatment, Archs gen. Psychiat., 37, 11, 10.1001/archpsyc.1980.01780140013001 Weinberger, 1980, Poor premorbid adjustment and CT scan sbnormalities in chronic schizophrenia, Am. J. Psychiat., 137, 1410, 10.1176/ajp.137.11.1410 Weinberger, 1981, Familial aspects of CT abnormalities in chronic schizophrenic patients, Psychiat. Res., 4, 65, 10.1016/0165-1781(81)90009-3 Weinberger, 1982, CT scans in schizophreniform disorder and other acute psychiatric patients, Archs gen. Psychiat., 39, 778, 10.1001/archpsyc.1982.04290070014004 Weinberger, D.R., Jeste, D.V., Teychenne, P.F. and Wyatt, R.J. (in press) Cerebral atrophy in elderly schizophrenic patients: effects of aging and of long-term institutionalization and neuroleptic therapy. In Schizophrenia, Paranoia and Schizophreniform Disorders of Late Life (Edited by Miller, N. and Cohen, G.) Guilford Press, New York. Weinberger, 1979, Lateral cerebral ventricular enlargement in chronic schizophrenia, Archs gen. Psychiat., 36, 735, 10.1001/archpsyc.1979.01780070013001 Weinberger, 1979, Structural abnormalities of the cerebral cortex in chronic schizophrenia, Archs gen. Psychiat., 36, 935, 10.1001/archpsyc.1979.01780090021002 Weinberger, 1979, Cerebellar atrophy in chronic schizophrenia, Lancet, i, 718, 10.1016/S0140-6736(79)91164-4 Weinberger, 1982, Cerebral ventricular size: a biological marker for subtyping chronic schizophrenia, 505 Weinberger, 1982, Cerebral morphology in schizophrenia, 148 Weinberger, D.R. (in press). The role of X-ray computed tomography in clinical psychiatry. In Handbook of Psychiatric Diagnostic Procedures (Edited by Hall, R.C.W. and Beresford, P) Spectrum, New York. Weinberger, 1983, Neuropathological studies of schizophrenia: a selective review, Schizophrenia Bull, 9, 193, 10.1093/schbul/9.2.193