Compound heterozygosity for an expanded (GAA) and a (GAAGGA) repeat at FXN locus: from a diagnostic pitfall to potential clues to the pathogenesis of Friedreich ataxia

Massimo Santoro1, Alessia Perna2, Piergiorgio La Rosa3, Sara Petrillo3, Fiorella Piemonte3, Salvatore Rossi2, Vittorio Riso4, Tommaso Nicoletti4, Anna Modoni5, Maria Grazia Pomponi6, Pietro Chiurazzi6, Gabriella Silvestri7
1IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
2Dept of Neuroscience, Faculty of Medicine and Surgery, Università Cattolica del Scaro Cuore, Rome, Italy
3Unit of Muscular and Neurodegenerative Diseases, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy
4Dept of Neuroscience, Faculty of Medicine and Surgery, Università Cattolica del Scaro Cuore, L.go F. Vito 1, 000168, Rome, Italy
5Institute of Neurology, Neuroscience Area, Neurology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
6Institute of Genomic Medicine, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy
7Institute of Neurology, Neuroscience Area, Neurology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy

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