Biến chứng của bệnh to đầu chi: tuyến giáp và đại tràng

Pituitary - Tập 20 - Trang 70-75 - 2016
Amit Tirosh1,2, Ilan Shimon1,2
1Institute of Endocrinology, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Tóm tắt

Trong bệnh to đầu chi, việc tiếp xúc lâu dài với nồng độ hormone tăng trưởng (GH) và yếu tố tăng trưởng giống insulin-1 (IGF-1) cao có thể dẫn đến các biến chứng cụ thể ở các cơ quan khác nhau trong cơ thể, bao gồm tuyến giáp và đại tràng. Chúng tôi sẽ xem xét bằng chứng hiện có liên quan đến các biến chứng điển hình ở tuyến giáp và đại tràng trong bệnh to đầu chi. Bài tổng quan này tóm tắt dữ liệu đã công bố về sự quan sát các bất thường cấu trúc không ung thư (nốt tuyến giáp, polyp đại tràng) và ung thư tuyến giáp cũng như ung thư đại tràng ở những bệnh nhân được chẩn đoán mắc bệnh to đầu chi. Các vi ung thư tuyến giáp có thể bị chẩn đoán quá mức trong số các bệnh nhân to đầu chi. Đối với ung thư đại tràng, không có đủ dữ liệu để gợi ý rằng nguy cơ ung thư đại tràng cao hơn ở bệnh nhân to đầu chi so với dân số chung.

Từ khóa

#bệnh to đầu chi #hormone tăng trưởng #yếu tố tăng trưởng giống insulin-1 #tuyến giáp #đại tràng #ung thư tuyến giáp #ung thư đại tràng #bất thường cấu trúc không ung thư.

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