Complementary and Alternative Medicine Treatments for Children with Autism Spectrum Disorders

2007, MMWR Surveill Summ, 56, 1 American Psychiatric Association, 2000 Gillberg, 2000, Autism and Asperger syndrome: coexistence with other clinical disorders, Acta Psychiatr Scand, 102, 321, 10.1034/j.1600-0447.2000.102005321.x Matson, 2007, Comorbid psychopathology with autism spectrum disorder in children: an overview, Res Dev Disabil, 28, 341, 10.1016/j.ridd.2005.12.004 2001 Myers, 2007, Management of children with autism spectrum disorders, Pediatrics, 120, 1162, 10.1542/peds.2007-2362 Davis, 2003, Use of complementary and alternative medicine by children in the United States, Arch Pediatr Adolesc Med, 157, 393, 10.1001/archpedi.157.4.393 Hanson, 2007, Use of complementary and alternative medicine among children diagnosed with autism spectrum disorder, J Autism Dev Disord, 37, 628, 10.1007/s10803-006-0192-0 Wong, 2006, Patterns of complementary and alternative medical therapy use in children diagnosed with autism spectrum disorders, J Autism Dev Disord, 36, 901, 10.1007/s10803-006-0131-0 Levy, 2003, Use of complementary and alternative medicine among children recently diagnosed with autistic spectrum disorder, J Dev Behav Pediatr, 24, 418, 10.1097/00004703-200312000-00003 Cuzzolin, 2003, Patterns and perceptions of complementary/alternative medicine among paediatricians and patients' mothers: a review of the literature, Eur J Pediatr, 162, 820, 10.1007/s00431-003-1313-9 Heuschkel, 2002, Complementary medicine use in children and young adults with inflammatory bowel disease, Am J Gastroenterol, 97, 382, 10.1111/j.1572-0241.2002.05474.x Shenfield, 2002, Survey of the use of complementary medicines and therapies in children with asthma, J Paediatr Child Health, 38, 252, 10.1046/j.1440-1754.2002.00770.x McCaffrey, 2007, Understanding patient preference for integrative medical care: results from patient focus groups, J Gen Intern Med, 22, 1500, 10.1007/s11606-007-0302-5 Simpson, 2001, Complementary medicine use in children: extent and reasons. A population-based study, Br J Gen Pract, 51, 914 Kazdin, 2005, Evidence-based assessment for children and adolescents: issues in measurement development and clinical application, J Clin Child Adolesc Psychol, 34, 548, 10.1207/s15374424jccp3403_10 Lilienfeld, 2005, Scientifically unsupported and supported interventions for childhood psychopathology: a summary, Pediatrics, 115, 761, 10.1542/peds.2004-1713 Sackett, 2007, Evidence based medicine: what it is and what it isn't. 1996, Clin Orthop Relat Res, 455, 3 Jensen, 2004, The effects of yoga on the attention and behavior of boys with attention-deficit/ hyperactivity disorder (ADHD), J Atten Disord, 7, 205, 10.1177/108705470400700403 Platania-Solazzo, 1992, Relaxation therapy reduces anxiety in child and adolescent psychiatric patients, Acta Paedopsychiatr, 55, 115 Uma, 1989, The integrated approach of yoga: a therapeutic tool for mentally retarded children. A one-year controlled study, J Ment Defic Res, 33, 415 Gold, 2006, Music therapy for autistic spectrum disorder, Cochrane Database Syst Rev, 2, 10.1002/14651858.CD004381.pub2 Kern, 2007, Use of songs to promote independence in morning greeting routines for young children with autism, J Autism Dev Disord, 37, 1264, 10.1007/s10803-006-0272-1 Heaton, 2005, Interval and contour processing in autism, J Autism Dev Disord, 35, 787, 10.1007/s10803-005-0024-7 Whippell, 2004, Music in intervention for children and adolescents with autism: a meta-analysis, J Music Ther, 41, 90, 10.1093/jmt/41.2.90 Nye, 2005, Combined vitamin B6-magnesium treatment in autism spectrum disorder, Cochrane Database Syst Rev, 10.1002/14651858.CD003497.pub2 Nye, 2002, Combined vitamin B6-magnesium treatment in autism spectrum disorder, Cochrane Database Syst Rev, 4, 10.1002/14651858.CD003497 Pfeiffer, 1995, Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes, J Autism Dev Disord, 25, 481, 10.1007/BF02178295 Findling, 1997, High-dose pyridoxine and magnesium administration in children with autistic disorder: an absence of salutary effects in a double-blind, placebo-controlled study, J Autism Dev Disord, 27, 467, 10.1023/A:1025861522935 Kuriyama, 2002, Pyridoxine treatment in a subgroup of children with pervasive developmental disorders, Dev Med Child Neurol, 44, 284, 10.1111/j.1469-8749.2002.tb00809.x Mousain-Bosc, 2006, Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. II. Pervasive developmental disorder-autism, Magnes Res, 19, 53 Bolman, 1999, A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder, J Autism Dev Disord, 29, 191, 10.1023/A:1023023820671 Kern, 2001, Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder, J Child Neurol, 16, 169, 10.1177/088307380101600303 Melke, 2008, Abnormal melatonin synthesis in autism spectrum disorders, Mol Psychiatry, 13, 90, 10.1038/sj.mp.4002016 Andersen, 2008, Melatonin for insomnia in children with autism spectrum disorders, J Child Neurol, 23, 482, 10.1177/0883073807309783 Garstang, 2006, Randomized controlled trial of melatonin for children with autistic spectrum disorders and sleep problems, Child Care Health Dev, 32, 585, 10.1111/j.1365-2214.2006.00616.x Dolske, 1993, A preliminary trial of ascorbic acid as supplemental therapy for autism, Prog Neuropsychopharmacol Biol Psychiatry, 17, 765, 10.1016/0278-5846(93)90058-Z McDougle, 2005, Neurochemistry in the pathophysiology of autism, J Clin Psychiatry, 66, 9 Ritvo, 1970, Increased blood serotonin and platelets in early infantile autism, Arch Gen Psychiatry, 23, 566, 10.1001/archpsyc.1970.01750060086009 McDougle, 1996, Effects of tryptophan depletion in drug-free adults with autistic disorder, Arch Gen Psychiatry, 53, 993, 10.1001/archpsyc.1996.01830110029004 Chez, 2002, Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders, J Child Neurol, 17, 833, 10.1177/08830738020170111501 Crill, 2007, The use of carnitine in pediatric nutrition, Nutr Clin Pract, 22, 204, 10.1177/0115426507022002204 Filipek, 2004, Relative carnitine deficiency in autism, J Autism Dev Disord, 34, 615, 10.1007/s10803-004-5283-1 Levy, 2005, Novel treatments for autistic spectrum disorders, Ment Retard Dev Disabil Res Rev, 11, 131, 10.1002/mrdd.20062 Sliwinski, 2006, Polyunsaturated fatty acids: do they have a role in the pathophysiology of autism?, Neuro Endocrinol Lett, 27, 465 Vancassel, 2001, Plasma fatty acid levels in autistic children, Prostaglandins Leukot Essent Fatty Acids, 65, 1, 10.1054/plef.2001.0281 Amminger, 2007, Omega-3 fatty acids supplementation in children with autism: a double-blind randomized, placebo-controlled pilot study, Biol Psychiatry, 61, 551, 10.1016/j.biopsych.2006.05.007 Kern, 2006, Evidence of toxicity, oxidative stress, and neuronal insult in autism, J Toxicol Environ Health B Crit Rev, 9, 485, 10.1080/10937400600882079 Amaral, 2008, Neuroanatomy of autism, Trends Neurosci, 31, 137, 10.1016/j.tins.2007.12.005 Glahn, 2007, Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function, Hum Brain Mapp, 28, 488, 10.1002/hbm.20401 Pardo, 2007, The neurobiology of autism, Brain Pathol, 17, 434, 10.1111/j.1750-3639.2007.00102.x James, 2004, Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism, Am J Clin Nutr, 80, 1611, 10.1093/ajcn/80.6.1611 James, 2006, Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism, Am J Med Genet B Neuropsychiatr Genet, 141, 947, 10.1002/ajmg.b.30366 Shattock, 1991, Proteins, peptides and autism. II. Implications for the education and care of people with autism, Brain Dysfunction, 4, 323 Knivsberg, 2002, A randomised, controlled study of dietary intervention in autistic syndromes, Nutr Neurosci, 5, 251, 10.1080/10284150290028945 Elder, 2006, The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial, J Autism Dev Disord, 36, 413, 10.1007/s10803-006-0079-0 Wolraich, 1995, The effect of sugar on behavior or cognition in children: a meta-analysis, JAMA, 274, 1617, 10.1001/jama.274.20.1617 Schab, 2004, Do artificial food colors promote hyperactivity in children with hyperactive syndromes? A meta-analysis of double-blind placebo-controlled trials, J Dev Behav Pediatr, 25, 423, 10.1097/00004703-200412000-00007 Erickson, 2005, Gastrointestinal factors in autistic disorder: a critical review, J Autism Dev Disord, 35, 713, 10.1007/s10803-005-0019-4 Kuddo, 2003, How common are gastrointestinal disorders in children with autism?, Curr Opin Pediatr, 15, 339, 10.1097/00008480-200306000-00020 Brudnak, 2002, Enzyme-based therapy for autism spectrum disorders—is it worth another look?, Med Hypotheses, 58, 422, 10.1054/mehy.2001.1513 Brudnak, 2002, Probiotics as an adjuvant to detoxification protocols, Med Hypotheses, 58, 382, 10.1054/mehy.2001.1442 Horvath, 1998, Improved social and language skills after secretin administration in patients with autistic spectrum disorders, J Assoc Acad Minor Phys, 9, 9 Williams, 2005, Intravenous secretin for autism spectrum disorder, Cochrane Database Syst Rev, 3, 10.1002/14651858.CD003495.pub2 Al-Waili, 2006, Effects of hyperbaric oxygen on inflammatory response to wound and trauma: possible mechanism of action, ScientificWorldJournal, 6, 425, 10.1100/tsw.2006.78 Calvert, 2007, Hyperbaric oxygen and cerebral physiology, Neurol Res, 29, 132, 10.1179/016164107X174156 McDonagh, 2003, Hyperbaric oxygen therapy for brain injury, cerebral palsy, and stroke, Evid Rep Technol Assess (Summ), 85, 1 McDonagh, 2007, Systematic review of hyperbaric oxygen therapy for cerebral palsy: the state of the evidence, Dev Med Child Neurol, 49, 942, 10.1111/j.1469-8749.2007.00942.x Rossignol, 2006, Hyperbaric oxygen therapy may improve symptoms in autistic children, Med Hypotheses, 67, 216, 10.1016/j.mehy.2006.02.009 Rossignol, 2007, The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study, BMC Pediatr, 7, 36, 10.1186/1471-2431-7-36 Doja, 2006, Immunizations and autism: a review of the literature, Can J Neurol Sci, 33, 341, 10.1017/S031716710000528X Parker, 2004, Thimerosal-containing vaccines and autistic spectrum disorder: a critical review of published original data, Pediatrics, 114, 793, 10.1542/peds.2004-0434 Bernard, 2001, Autism: a novel form of mercury poisoning, Med Hypotheses, 56, 462, 10.1054/mehy.2000.1281 Ng, 2007, Low-level chronic mercury exposure in children and adolescents: meta-analysis, Pediatr Int, 49, 80, 10.1111/j.1442-200X.2007.02303.x DeStefano, 2007, Vaccines and autism: evidence does not support a causal association, Clin Pharmacol Ther, 82, 756, 10.1038/sj.clpt.6100407 Hviid, 2006, Postlicensure epidemiology of childhood vaccination: the Danish experience, Expert Rev Vaccines, 5, 641, 10.1586/14760584.5.5.641 Hviid, 2003, Association between thimerosal-containing vaccine and autism, JAMA, 290, 1763, 10.1001/jama.290.13.1763 Madsen, 2003, Thimerosal and the occurrence of autism: negative ecological evidence from Danish population-based data, Pediatrics, 112, 604, 10.1542/peds.112.3.604 McCormick, 2003, The autism “epidemic”: impressions from the perspective of immunization safety review, Ambul Pediatr, 3, 119, 10.1367/1539-4409(2003)003<0119:TAEIFT>2.0.CO;2 Nelson, 2003, Thimerosal and autism?, Pediatrics, 111, 674, 10.1542/peds.111.3.674 Offit, 2004, Thimerosal and autism, Mol Psychiatry, 9, 644, 10.1038/sj.mp.4001522 Rutter, 2005, Incidence of autism spectrum disorders: changes over time and their meaning, Acta Paediatr, 94, 2, 10.1080/08035250410023124 Stehr-Green, 2003, Autism and thimerosal-containing vaccines: lack of consistent evidence for an association, Am J Prev Med, 25, 101, 10.1016/S0749-3797(03)00113-2 Stokstad, 2003, Epidemiology: vaccine-autism link dealt blow, Science, 301, 1454, 10.1126/science.301.5639.1454a Thompson, 2007, Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years, N Engl J Med, 357, 1281, 10.1056/NEJMoa071434 Verstraeten, 2003, Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases, Pediatrics, 112, 1039, 10.1542/peds.112.5.1039 Brown, 2006, Deaths resulting from hypocalcemia after administration of edetate disodium: 2003–2005, Pediatrics, 118, e534, 10.1542/peds.2006-0858 Stern, 2005, Immune function in autistic children, Ann Allergy Asthma Immunol, 95, 558, 10.1016/S1081-1206(10)61019-8 Wills, 2007, Autoantibodies in autism spectrum disorders (ASD), Ann N Y Acad Sci, 1107, 79, 10.1196/annals.1381.009 Jyonouchi, 2005, Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention, Neuropsychobiology, 51, 77, 10.1159/000084164 Gupta, 1996, Dysregulated immune system in children with autism: beneficial effects of intravenous immune globulin on autistic characteristics, J Autism Dev Disord, 26, 439, 10.1007/BF02172828 DelGiudice-Asch, 1999, Brief report: a pilot open clinical trial of intravenous immunoglobulin in childhood autism, J Autism Dev Disord, 29, 157, 10.1023/A:1023096728131 Gupta, 2000, Immunological treatments for autism, J Autism Dev Disord, 30, 475, 10.1023/A:1005568027292 Niehus, 2006, Early medical history of children with autism spectrum disorders, J Dev Behav Pediatr, 27, S120, 10.1097/00004703-200604002-00010 Rosen, 2007, Infection in the first 2 years of life and autism spectrum disorders, Pediatrics, 119, e61, 10.1542/peds.2006-1788 Finegold, 2002, Gastrointestinal microflora studies in late-onset autism, Clin Infect Dis, 35, S6, 10.1086/341914 Fernell, 2007, No evidence for a clear link between active intestinal inflammation and autism based on analyses of faecal calprotectin and rectal nitric oxide, Acta Paediatr, 96, 1076, 10.1111/j.1651-2227.2007.00298.x Sandler, 2000, Short-term benefit from oral vancomycin treatment of regressive-onset autism, J Child Neurol, 15, 429, 10.1177/088307380001500701 Shaw, 1995, Increased urinary excretion of analogs of Krebs cycle metabolites and arabinose in two brothers with autistic features, Clin Chem, 41, 1094, 10.1093/clinchem/41.8.1094 Crook, 1987, Nutrition, food allergies, and environmental toxins, J Learn Disabil, 20, 260 Vohra, 2007, Adverse events associated with pediatric spinal manipulation: a systematic review, Pediatrics, 119, e275, 10.1542/peds.2006-1392 Downey, 2006, Craniosacral therapy: the effects of cranial manipulation on intracranial pressure and cranial bone movement, J Orthop Sports Phys Ther, 36, 845, 10.2519/jospt.2006.2238 Moran, 2001, Intraexaminer and interexaminer reliability for palpation of the cranial rhythmic impulse at the head and sacrum, J Manipulative Physiol Ther, 24, 183, 10.1016/S0161-4754(01)62711-8 Silva, 2007, Improvement in sensory impairment and social interaction in young children with autism following treatment with an original Qigong massage methodology, Am J Chin Med, 35, 393, 10.1142/S0192415X07004916 Williams, 2006, Evaluating effects of aromatherapy massage on sleep in children with autism: a pilot study, Evid Based Complement Alternat Med, 3, 373, 10.1093/ecam/nel017 Sinha, 2006, Auditory integration training and other sound therapies for autism spectrum disorders: a systematic review, Arch Dis Child, 91, 1018, 10.1136/adc.2006.094649 Sinha, 2004, Auditory integration training and other sound therapies for autism spectrum disorders, Cochrane Database Syst Rev, 10.1002/14651858.CD003681.pub2 American Academy of Pediatrics, 1998, Committee on children with disabilities: auditory integration training and facilitated communication for autism, Pediatrics, 102, 431, 10.1542/peds.102.2.431 Frye, 2008, Transcranial magnetic stimulation in child neurology: current and future directions, J Child Neurol, 23, 79, 10.1177/0883073807307972 Oberman, 2007, The simulating social mind: the role of the mirror neuron system and simulation in the social and communicative deficits of autism spectrum disorders, Psychol Bull, 133, 310, 10.1037/0033-2909.133.2.310 Hoeppner, 2008, Impaired transcallosally mediated motor inhibition in adults with attention-deficit/hyperactivity disorder is modulated by methylphenidate, J Neural Transm, 115, 777, 10.1007/s00702-007-0008-1 Cohen, 2005, Complementary therapies in pediatrics: a legal perspective, Pediatrics, 115, 774, 10.1542/peds.2004-1093 Fugh-Berman, 2000, Herb-drug interactions, Lancet, 355, 134, 10.1016/S0140-6736(99)06457-0