Sheng Wang1, Wei Chen1, Ai‐Lin Liu1, Hong Lei1, Hao‐Hua Deng1, Xinhua Lin1
1Department of Pharmaceutical Analysis, Fujian Medical University, Fuzhou 350004, China
Tóm tắt
AbstractThe origin of the peroxidase‐like activity of gold nanoparticles and the impact of surface modification are studied. Furthermore, some influencing factors, such as fabrication process, redox property of the modifier, and charge property of the substrate, are investigated. Compared to amino‐modified or citrate‐capped gold nanoparticles, unmodified gold nanoparticles show significantly higher catalytic activity toward peroxidase substrates, that is, the superficial gold atoms are a contributing factor to the observed peroxidase‐like activity. The different catalytic activities of amino‐modified and citrate‐capped gold nanoparticles toward 3,3′,5,5′‐tetramethylbenzidine (TMB) and 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) diammonium salt (ABTS) show that the charge characteristics of the nanoparticles and the substrate also play an important role in the catalytic reactions.
