Comparison of Inducibility of CYP1A and CYP3A mRNAs by Prototypical Inducers in Primary Cultures of Human, Cynomolgus Monkey, and Rat Hepatocytes

Drug Metabolism and Pharmacokinetics - Tập 22 - Trang 178-186 - 2007
Masuhiro Nishimura1, Akiko Koeda2, Yasuyuki Suganuma2, Emako Suzuki2, Takefumi Shimizu2, Mitsuo Nakayama1, Tetsuo Satoh2,3, Shizuo Narimatsu4, Shinsaku Naito1
1Department of Drug Metabolism, Division of Pharmacology, Drug Safety and Metabolism, Otsuka Pharmaceutical Factory, Inc., Tokushima, Japan
2Ina Research Inc., Nagano, Japan
3Non-Profit Organization Human & Animal Bridging Research Organization, Chiba, Japan
4Laboratory of Health Chemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

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