Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma

Wiley - Tập 84 Số 5 - Trang 650-655 - 2006
Paolo Brusini1, Maria Letizia Salvetat, Marco Zeppieri, Claudia Tosoni, Lucia Parisi, Mirella Felletti
1Department of Ophthalmology, Santa Maria della Misericordia Hospital, Udine, Italy. [email protected]

Tóm tắt

Abstract.Purpose:  To compare the abilities of scanning laser polarimetry with the variable corneal compensator (GDx VCC) with those of optical coherence tomography (Stratus OCT) in discriminating between healthy and early‐to‐moderate perimetric glaucomatous eyes.Methods:  A total of 95 glaucomatous patients (mean deviation − 3.7 ± 3.0 dB, pattern standard deviation 4.5 ± 2.7 dB) and 62 control subjects underwent imaging by the GDx VCC and Stratus OCT using both optic nerve head (ONH) and retinal nerve fibre layer (RNFL) scan protocols. One eye per patient was considered. Sensitivity at ≥ 90% specificity and area under the receiver operating characteristic curve (AROC) were calculated for each GDx VCC and Stratus OCT index.Results:  The largest AROCs with Stratus OCT were associated with cup : disc area ratio (0.88) for ONH scan indices, and with average thickness (0.84) for RNFL scan indices. The nerve fibre indicator provided the greatest AROC for the GDx VCC indices (0.85).Conclusions:  Both the GDx VCC and Stratus OCT instruments were shown to be useful in the detection of glaucomatous damage. The best performing indices for the GDx VCC and Stratus OCT with both ONH and RNFL scans gave similar AROCs, showing a moderate sensitivity in early‐to‐moderate glaucoma patients.

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Wiley

Tập 84 Số 5

650-655

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