Comparing and combining gamma-hydroxybutyric acid (GHB) and naltrexone in maintaining abstinence from alcohol: An open randomised comparative study

European Neuropsychopharmacology - Tập 17 - Trang 781-789 - 2007
Fabio Caputo1,2, Giovanni Addolorato3, Michela Stoppo1, Sara Francini1, Teo Vignoli1, Francesca Lorenzini1, Arfedele Del Re2, Claudio Comaschi2, Pietro Andreone1, Franco Trevisani1, Mauro Bernardi1, Alcohol Treatment Study Group
1“G. Fontana” Centre for the Study and Multidisciplinary Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
2Unit for Addiction Treatment, Department of Mental Health, ASL of Bologna, Italy
3Institute of Internal Medicine, Catholic University of Sacred Hearth, Roma, Italy

Tài liệu tham khảo

Addolorato, 1996, An open multicentric study evaluating 4-hydroxybutyric acid sodium salt in the medium term treatment of 179 alcohol dependent subjects, Alcohol Alcohol., 81, 341, 10.1093/oxfordjournals.alcalc.a008160 Addolorato, 1999, A case of gamma-hydroxybutyric acid withdrawal syndrome during alcohol addiction treatment: utility of diazepam administration, Clin. Neuropharmacol., 22, 60, 10.1097/00002826-199901000-00011 Addolorato, 2000, Gamma-hydroxybutyric acid efficacy, potential abuse, and dependence in the treatment of alcohol addiction, Alcohol, 20, 217, 10.1016/S0741-8329(99)00084-1 Agabio, 1998, Gamma-hydroxybutyric acid reducing effect on ethanol intake: evidence in favour of a substitution mechanism, Alcohol Alcohol., 33, 465, 10.1093/alcalc/33.5.465 Ait-Daoud, 2001, Combining ondansetron and naltrexone treats biological alcoholics: corroboration of self-reported drinking by serum carbohydrate deficient transferring, a biomarker, Alcohol. Clin. Exp. Res., 25, 847, 10.1111/j.1530-0277.2001.tb02289.x American Psychiatric Combination, 2000 Anton, 2006, COMBINE Study Research Group. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial, JAMA, 295, 2003, 10.1001/jama.295.17.2003 Benjamin, 1993, Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats, Brain. Res., 621, 137, 10.1016/0006-8993(93)90309-B Besson, 1998, Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study, Alcohol. Clin. Exp. Res., 22, 573, 10.1111/j.1530-0277.1998.tb04295.x Caputo, 2003, Gamma-hydroxybutyric acid versus naltrexone in maintaining alcohol abstinence: an open randomized comparative study, Drug Alcohol. Depend., 70, 85, 10.1016/S0376-8716(02)00340-X Caputo, 2005, Suppression of craving for γ-hydroxybutyric acid by naltrexone administration: three case reports, Clin. Neuropharmacol., 28, 87, 10.1097/01.wnf.0000159954.49393.76 Chick, 2000, A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse, Alcohol Alcohol., 35, 587, 10.1093/alcalc/35.6.587 Colombo, 1995, Oral self-administration of gamma-hydroxybutyric acid in the rat, Eur. J. Pharmacol., 285, 103, 10.1016/0014-2999(95)00493-5 Conway, 2006, Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions, J. Clin. Psychiatry, 67, 247, 10.4088/JCP.v67n0211 Crowely, 1985, Naltrexone-induced dysphoria in former opioid addicts, Am. J. Psychiatry, 142, 1081, 10.1176/ajp.142.9.1081 Devoto, 1994, Naloxone antagonizes ethanol but not γ-hydroxybutyrate-induced sleep in mice, Eur. J. Pharmacol., 252, 321, 10.1016/0014-2999(94)90179-1 Drasbek, 2006, Gamma-hydroxybutyrate—a drug of abuse, Acta Neurol. Scand., 114, 145, 10.1111/j.1600-0404.2006.00712.x Feigenbaum, 1996, Lack of effect of γ-hydroxybutyrate on μ, κ and δ opioid receptor binding, Neuroscience, 212, 5 Feeney, 2006, Combined acamprosate and naltrexone, with cognitive behavioural therapy is superior to either medication alone for alcohol abstinence: a single centres' experience with pharmacotherapy, Alcohol Alcohol., 41, 321, 10.1093/alcalc/agl007 Gallimberti, 1992, Gamma-hydroxybutyric acid in the treatment of alcohol dependence: a double blind study, Alcohol. Clin. Exp. Res., 16, 673, 10.1111/j.1530-0277.1992.tb00658.x Gallimberti, 2000, Gamma-hydroxybutyric acid in the treatment of alcohol and heroin dependence, Alcohol, 20, 257, 10.1016/S0741-8329(99)00089-0 Garbutt, 2005, Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomised controlled trial, JAMA, 293, 1617, 10.1001/jama.293.13.1617 Gessa, 1985, Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area, Brain. Res., 348, 201, 10.1016/0006-8993(85)90381-6 Gessa, 2000, Mechanism of the anti-alcohol effect of gamma hydroxybutyric acid (GHB), Alcohol, 20, 271, 10.1016/S0741-8329(99)00091-9 Grant, 2004, Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions, Arch. Gen. Psychiatry, 61, 807, 10.1001/archpsyc.61.8.807 Heilig, 2006, Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms, Pharmacol. Ther., 111, 855, 10.1016/j.pharmthera.2006.02.001 International Narcotics Control Board (2003). List of psychotropic substances under international control: in accordance with the Convention on Psychotropic Substances of 1971. Green List: annex to the annual statistic report on psychotropic substances (form P) 23RD. Johnson, 2005, Safety and efficacy of GABAergic medications for treating alcoholism, Alcohol. Clin. Exp. Res., 29, 248, 10.1097/01.ALC.0000153542.10188.B0 Kessler, 2004, The epidemiology of dual diagnosis, Biol. Psychiatry, 56, 730, 10.1016/j.biopsych.2004.06.034 Kiefer, 2003, Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study, Arch. Gen. Psychiatry, 60, 92, 10.1001/archpsyc.60.1.92 Kiefer, 2005, Pharmacological relapse prevention of alcoholism: clinical predictors of outcome, Eur. Addict. Res., 11, 83, 10.1159/000083037 Kranzler, 2000, Naltrexone vs. Nefazodone for treatment of alcohol dependence. A placebo-controlled trial, Neuropsychopharmacology, 22, 493, 10.1016/S0893-133X(99)00135-9 Krystal, 2001, Naltrexone in the treatment of alcohol dependence, N. Engl. J. Med., 345, 1734, 10.1056/NEJMoa011127 Lehert, 1993, Review and discussion of statistical analysis of controlled clinical trials in alcoholism, Alcohol Alcohol., 28, 157 Lesch, 1996, Subtypes of alcoholism and their role in therapy, Alcohol Alcohol., 1, 63, 10.1093/oxfordjournals.alcalc.a008221 Lewis, 1996, Alcohol reinforcement and neuropharmacological therapeutics, Alcohol Alcohol., 31, 17, 10.1093/oxfordjournals.alcalc.a008214 Maitre, 1990, A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties, J. Pharmacol. Exp. Ther., 255, 657 Mann, 2004, Pharmacotherapy of alcohol dependence, Drugs, 18, 485 Mendelson, 1979, Effects of naltrexone on mood and neuroendocrine function in normal adult males, Psychoneuroendocrinology, 3, 231, 10.1016/0306-4530(78)90013-6 Morley, 2006, Naltrexone versus acamprosate in the treatment of alcohol dependence: a multi-centre, randomised, double-blind, placebo-controlled trial, Addiction, 101, 1451, 10.1111/j.1360-0443.2006.01555.x Nicholson, 2001, GHB: a new and novel drug of abuse, Drug Alcohol. Depend., 63, 1, 10.1016/S0376-8716(00)00191-5 Niemelä, 2007, Biomarkers in alcoholism, Clin. Chem., 377, 39, 10.1016/j.cca.2006.08.035 Nimmerrichter, 2002, Double-blind controlled trial of gamma-hydroxybutyrate and clomethiazole in the treatment of alcohol withdrawal, Alcohol Alcohol., 37, 67, 10.1093/alcalc/37.1.67 O'Malley, 1992, Naltrexone and coping skills therapy for alcohol dependence, Arch. Gen. Psychiatry, 49, 881, 10.1001/archpsyc.1992.01820110045007 Petrakis, 2005, Naltrexone and disulfiram in patients with alcohol dependence and comorbid psychiatric disorders, Biol. Psychiatry, 57, 1128, 10.1016/j.biopsych.2005.02.016 Secretary and Human Services, 1997 Sinclair, 2001, Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism, Alcohol Alcohol., 36, 2, 10.1093/alcalc/36.1.2 Sillanaukee, 1996, Laboratory markers of alcohol abuse, Alcohol Alcohol., 31, 613, 10.1093/oxfordjournals.alcalc.a008199 Snead, 1980, Naloxone overcomes the dopaminergic, EEG and behavioural effect of γ-hydroxybutyrate, Neurology, 30, 832, 10.1212/WNL.30.8.832 Snead, 1982, The epileptogenic spectrum of opiate agonists, Neuropharmacology, 21, 1137, 10.1016/0028-3908(82)90171-X Snead, 2005, Gamma-hydroxybutyric acid, N. Engl. J. Med., 352, 2721, 10.1056/NEJMra044047 Staines, 2001, Polysubstance use among alcoholics, J. Addict. Dis., 20, 53, 10.1300/J069v20n04_06 Volpicelli, 1997, Naltrexone and alcohol dependence, Arch. Gen. Psychiatry, 54, 737, 10.1001/archpsyc.1997.01830200071010