Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China
Tóm tắt
EQ-5D-3L has been used in the National Health Services Survey of China since 2008 to monitor population health. The five-level version of EQ-5D was developed, but there lacks evidence to support the use of five-level version of EQ-5D in China. This study was conducted to compare the measurement properties of both the EQ-5D-3L and EQ-5D-5L in quantifying health-related quality of life (HRQoL) burden for 4 different health conditions in China. Participants from China were recruited to complete the 3L and 5L questionnaire via Internet. Quota was set to recruit five groups of individuals, with one group of individuals without any health condition and one group of generalized anxiety disorder (GAD), HIV/AIDS, chronic Hepatitis B (CHB), or depression, respectively. The 3L and 5L were compared in terms of response distributions, percentages of reporting ‘no problems’, index value distributions, known-group validity and their relative efficiency. In total, 500 individuals completed the online survey, including 140 healthy individuals, 122 individuals with hepatitis B, 107 with depression, 90 individuals with GAD and 101 with HIV/AIDS. 5L also had smoother and less clustered index value distributions. Healthy group showed different response distributions to the four condition groups. The percentage of reporting ‘no problems’ decreased significantly in the 5L in all domains (P < 0.01), especially in the pain/discomfort dimension (relative difference: 43.10%). Relative efficiency suggested that 5L had a higher absolute discriminatory power than the 3L version between healthy participant and the other 4 condition groups, especially for the HIV/AIDS group when the 3L results was not significant. The 5L version may be preferable to the 3L, as it demonstrated superior performance with respect to higher sensitivity to mild health problems, better relative efficiency and responses and index value distributions.
Tài liệu tham khảo
Devlin, N.J., Brooks, R.: EQ-5D and the EuroQol Group: past, present and future. Appl. Health Econ. Health Policy. 15(2), 127–137 (2017). https://doi.org/10.1007/s40258-017-0310-5
Szende, A., Janssen, B.: Socio-demographic indicators based on EQ-5D. In: Szende, A., Janssen, B., Cabases, J. (eds.) Self-Reported Population Health: An International Perspective Based on EQ-5D, pp. 37–46. Springer, Dordrecht (2014)
Devlin, N.J., Krabbe, P.F.: The development of new research methods for the valuation of EQ-5D-5L. Eur. J. Health Econ. 14(Suppl 1), S1-3 (2013). https://doi.org/10.1007/s10198-013-0502-3
Janssen, M.F., Pickard, A.S., Golicki, D., Gudex, C., Niewada, M., Scalone, L., et al.: Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: a multi-country study. Qual. Life Res. 22(7), 1717–1727 (2013). https://doi.org/10.1007/s11136-012-0322-4
Herdman, M., Gudex, C., Lloyd, A., Janssen, M.F., Kind, P., Parkin, D., et al.: Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Qual. Life Res. 20(10), 1727–1736 (2011). https://doi.org/10.1007/s11136-011-9903-x
Han, Y., Wu, J., Cong, H., Zhou, J., Xu, C.: Validity and sensitivity of the SF-6D and EQ-5D in Chinese patients with stable angina pectoris. Chin. J. Health Stat. 30(06), 829–832 (2013). (in Chinese)
Cheung, P.W.H., Wong, C.K.H., Samartzis, D., Luk, K.D.K., Lam, C.L.K., Cheung, K.M.C., et al.: Psychometric validation of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) in Chinese patients with adolescent idiopathic scoliosis. Scoliosis Spinal Disord. 11, 19 (2016). https://doi.org/10.1186/s13013-016-0083-x
Wang, S.L., Wu, B., Zhu, L.A., Leng, L., Bucala, R., Lu, L.J.: Construct and criterion validity of the Euro Qol-5D in patients with systemic lupus erythematosus. PLoS One 9(6), e98883 (2014). https://doi.org/10.1371/journal.pone.0098883
Yao, J., Liang, Y., Xu, Y., Guo, L., Yang, L., Pan, J., et al.: Analysis of the measurement characteristics of Chinese version of EQ-5D-3L applied in population with chronic disease: Rasch Model. Chin. J. Health Stat. 35(05), 681–683 (2018). (in Chinese)
Jia, Y., Cui, F., Zhang, D., Zhang, G., Gong, X., Wang, F., et al.: Investigation on the applicability of EQ-5D-5L in Chinese Patients with chronic hepatitis B. Chin. J. Vaccines Immun. 19(06), 492–497 (2013). (in Chinese)
Tsang, H.H.L., Cheung, J.P.Y., Wong, C.K.H., Cheung, P.W.H., Lau, C.S., Chung, H.Y.: Psychometric validation of the EuroQoL 5-dimension (EQ-5D) questionnaire in patients with spondyloarthritis. Arthritis Res. Ther. 21(1), 41 (2019). https://doi.org/10.1186/s13075-019-1826-x
Xu, R., Dong, D., Luo, N., Wong, E., Wu, Y., Yu, S., et al.: Evaluating the psychometric properties of the EQ-5D-5L and SF-6D among patients with haemophilia. Eur. J. Health Econ. 22(4), 547–557 (2021). https://doi.org/10.1007/s10198-021-01273-5
Zhu, J., Yan, X., Liu, C., Wang, H., Wang, L., Cao, S., et al.: Comparing EQ-5D-3L and EQ-5D-5L performance in common cancers: suggestions for instrument choosing. Qual. Life Res. 30(3), 841–854 (2021). https://doi.org/10.1007/s11136-020-02636-w
Jia, Y., Cui, F., Li, L., Zhang, D., Zhang, G., Wang, F., et al.: Comparison between the EQ-5D-5L and the EQ-5D-3L in patients with hepatitis B. Qual. Life Res. 23(8), 2355–2363 (2014). https://doi.org/10.1007/s11136-014-0670-3
Zeng, X., Sui, M., Liu, B., Yang, H., Liu, R., Tan, R., et al.: Measurement properties of the EQ-5D-5L and EQ-5D-3L in six commonly diagnosed cancers. Patient 14(2), 209–222 (2021). https://doi.org/10.1007/s40271-020-00466-z
You, R., Liu, J., Yang, Z., Pan, C., Ma, Q., Luo, N.: Comparing the performance of the EQ-5D-3 L and the EQ-5D-5 L in an elderly Chinese population. Health Qual. Life Outcomes 18(1), 97 (2020). https://doi.org/10.1186/s12955-020-01324-0
Yu, H., Zeng, X., Sui, M., Liu, R., Tan, R., Yang, J., et al.: A head-to-head comparison of measurement properties of the EQ-5D-3L and EQ-5D-5L in acute myeloid leukemia patients. Qual. Life Res. 30(3), 855–866 (2021). https://doi.org/10.1007/s11136-020-02644-w
Jiang, J., Hong, Y., Zhang, T., Yang, Z., Lin, T., Liang, Z., et al.: Comparing the measurement properties of the EQ-5D-5L and the EQ-5D-3L in hypertensive patients living in rural China. Qual. Life Res. 30(7), 2045–2060 (2021). https://doi.org/10.1007/s11136-021-02786-5
Pan, C., Sun, H., Wang, X., Ma, Q., Xu, Y., Luo, N., et al.: The EQ-5D-5L index score is more discriminative than the EQ-5D-3L index score in diabetes patients. Qual. Life Res. 24(7), 1767–1774 (2015). https://doi.org/10.1007/s11136-014-0902-6
Zhou, T., Guan, H., Liu, G., Ma, A.: Comparison analysis on the EQ-5D-5L and the EQ-5D-3L for general population in China. Chin. Health Econ. 35(03), 17–20 (2016). (in Chinese)
Cai, Y., Wu, H., Yang, Z.: Comparison analysis of European quality of life-5 dimensions with three-level and five-level based on four types of people in China. Chin. J. Dis. Control Prev. 24(10), 1190–1194 (2020). ((in Chinese))
Zhao, Z., Xu, S., Wang, X., Zhang, P., Bi, Y., Li, D., et al.: Scientific evaluation of the European Five-dimensional Health Scale inpatients with chronic heart failure. Chin. J. Tradit. Chin. Med. Pharm. 34(04), 1715–1718 (2019). (in Chinese)
Tsang, H.H.L., Wong, C.K.H., Cheung, P.W.H., Lau, C.S., Chung, H.Y., Cheung, J.P.Y.: Responsiveness of the EuroQoL 5-Dimension (EQ-5D) questionnaire in patients with spondyloarthritis. BMC Musculoskelet. Disord. 22(1), 439 (2021). https://doi.org/10.1186/s12891-021-04315-4
Cheung, P.W.H., Wong, C.K.H., Lau, S.T., Cheung, J.P.Y.: Responsiveness of the EuroQoL 5-dimension (EQ-5D) in adolescent idiopathic scoliosis. Eur. Spine J. 27(2), 278–285 (2018). https://doi.org/10.1007/s00586-017-5330-1
Xing, Y., Ma, A.: An empirical study comparing the Chinese versions of EQ-5D-3L and EQ-5D-5L. Shanghai Med. Pharma. J. 34(07), 27–31 (2013). (in Chinese)
Hu, H., Shen, W., Jia, M., Yu, G., Mei, X., Bian, Q., et al.: Reliability and validity of the Chinese Version of the EQ-5D-3L in patients of chronic kidney disease. Chin. J. Integr. Tradit. Western Nephrol. 13(08), 690–693 (2012). (in Chinese)
Hu, X., Jing, M., Zhang, M., Yan, X., Huang, Y.: The reliability and validity of EQ-5D-3L in Uygur cervical cancer patients. J. Shihezi Univ. (Nat. Sci.). 37(06), 780–785 (2019). (in Chinese)
Qiu, Y.: Reliability and validity of the Chinese Version of EQ-5D in the knee osteoarthritis [Master, Capital Institute of Physical Education]. (2015). (in Chinese)
Xia, J., Wu, N., Ma, T., Yu, C., Li, N.: Evaluation of reliability and validity of EQ-5D-5L based on residents in Southwest China. J. Sichuan Univ. (Med. Sci. Ed.) 51(05), 691–694 (2020). (in Chinese)
Xing, Y., Ma, A.: Study on reliability and validity of Chinese version of EQ-5D-5L. Shanghai Med. Pharma. J. 34(09), 40–43 (2013). (in Chinese)
Fang, H., Farooq, U., Wang, D., Yu, F., Younus, M.I., Guo, X.: Reliability and validity of the EQ-5D-3L for Kashin-Beck disease in China. Springerplus 5(1), 1924 (2016). https://doi.org/10.1186/s40064-016-3613-3
Li, L., Liu, C., Cai, X., Yu, H., Zeng, X., Sui, M., et al.: Validity and reliability of the EQ-5D-5L in family caregivers of leukemia patients. BMC Cancer 19(1), 522 (2019). https://doi.org/10.1186/s12885-019-5721-2
Yang, F., Jiang, S., He, X., Li, H., Wu, H., Zhang, T., et al.: Do rural residents in China understand EQ-5D-5L as intended? Evidence from a qualitative study. Pharmacoecon. Open 5(1), 101–109 (2021). https://doi.org/10.1007/s41669-020-00212-z
Dai, L., Wen, Y., Lu, T., Cai, J., Wang, L., Qin, M., et al.: Measurement characteristics evaluation of SF-HSTCM and EQ-5D-3L among patients with stroke. J. Cap. Med. Univ. 40(04), 627–634 (2019). (in Chinese)
Peasgood, T., Mukuria, C., Brazier, J., Marten, O., Kreimeier, S., Luo, N., et al.: Developing a new generic health and wellbeing measure: psychometric survey results for the EQ health and wellbeing. Value Health. (2022). https://doi.org/10.1016/j.jval.2021.11.1361
Yfantopoulos, J., Chantzaras, A., Kontodimas, S.: Assessment of the psychometric properties of the EQ-5D-3L and EQ-5D-5L instruments in psoriasis. Arch. Dermatol. Res. 309(5), 357–370 (2017). https://doi.org/10.1007/s00403-017-1743-2
Bhadhuri, A., Kind, P., Salari, P., Jungo, K.T., Boland, B., Byrne, S., et al.: Measurement properties of EQ-5D-3L and EQ-5D-5L in recording self-reported health status in older patients with substantial multimorbidity and polypharmacy. Health Qual. Life Outcomes 18(1), 317 (2020). https://doi.org/10.1186/s12955-020-01564-0
Poor, A.K., Rencz, F., Brodszky, V., Gulacsi, L., Beretzky, Z., Hidvegi, B., et al.: Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L in psoriasis patients. Qual. Life Res. 26(12), 3409–3419 (2017). https://doi.org/10.1007/s11136-017-1699-x
Gandhi, M., Ang, M., Teo, K., Wong, C.W., Wei, Y.C.H., Tan, R.L.Y., et al.: EQ-5D-5L is more responsive than EQ-5D-3L to treatment benefit of cataract surgery. Patient-Patient Cent. Outcomes Res. 12(4), 383–392 (2019)
Liu, G.G., Wu, H., Li, M., Gao, C., Luo, N.: Chinese time trade-off values for EQ-5D health states. Value Health 17(5), 597–604 (2014). https://doi.org/10.1016/j.jval.2014.05.007
Luo, N., Liu, G., Li, M., Guan, H., Jin, X., Rand-Hendriksen, K.: Estimating an EQ-5D-5L value set for China. Value Health 20(4), 662–669 (2017). https://doi.org/10.1016/j.jval.2016.11.016
Parkin, D., Devlin, N., Feng, Y.: What determines the shape of an EQ-5D index distribution? Med. Decis. Making 36(8), 941–951 (2016). https://doi.org/10.1177/0272989X16645581
Terwee, C.B., Bot, S.D.M., de Boer, M.R., van der Windt, D.A.W.M., Knol, D.L., Dekker, J., Bouter, L.A., et al.: Quality criteria were proposed for measurement properties of health status questionnaires. J. Clin. Epidemiol. 60(1), 34–42 (2007)
Vickrey, B.G., Hays, R.D., Genovese, B.J., Myers, L.W., Ellison, G.W.: Comparison of a generic to disease-targeted health-related quality-of-life measures for multiple sclerosis. J. Clin. Epidemiol. 50(5), 557–569 (1997). https://doi.org/10.1016/s0895-4356(97)00001-2
Luo, N., Johnson, J.A., Shaw, J.W., Coons, S.J.: Relative efficiency of the EQ-5D, HUI2, and HUI3 Index Scores in measuring health burden of chronic medical conditions in a population health survey in the United States. Med. Care 47(1), 53–60 (2009)
Kennedy-Martin, M., Slaap, B., Herdman, M., van Reenen, M., Kennedy-Martin, T., Greiner, W., et al.: Which multi-attribute utility instruments are recommended for use in cost-utility analysis? A review of national health technology assessment (HTA) guidelines. Eur. J. Health Econ. 21(8), 1245–1257 (2020). https://doi.org/10.1007/s10198-020-01195-8
Buchholz, I., Janssen, M.F., Kohlmann, T., Feng, Y.S.: A systematic review of studies comparing the measurement properties of the three-level and five-level versions of the EQ-5D. Pharmacoeconomics 36(6), 645–661 (2018). https://doi.org/10.1007/s40273-018-0642-5
Janssen, M.F., Bonsel, G.J., Luo, N.: Is EQ-5D-5L better than EQ-5D-3L? A head-to-head comparison of descriptive systems and value sets from seven countries. Pharmacoeconomics 36(6), 675–697 (2018). https://doi.org/10.1007/s40273-018-0623-8
Feng, Y., Devlin, N., Bateman, A., Zamora, B., Parkin, D.: distribution of the EQ-5D-5L profiles and values in three patient groups. Value Health. 22(3), 355–361 (2019). https://doi.org/10.1016/j.jval.2018.08.012