Comparative tissue morphology in using prostheses from polypropylene and polytetrafluoretilen
Tóm tắt
To treat hernias, polymer net implants are widely used. We carried out a comparative study of the morphological picture of inflammation, cellular composition of tissues, and dynamics of scar formation in mice in using the implants Esfil and Uniflex under conditions of single and double introduction of cultivated fibroblasts and without fibroblasts in the area of disposition of the endoprostheses. A more expressed inflammatory reaction throughout the entire period of time was observed in implantation of the material Esfil. In using the material Uniflex, there was revealed a higher percent of fibroblasts than in using the Esfil prosthesis. Introduction of cultivated fibroblasts in using both materials modified the curve of dynamics of the inflammatory process by making it smoother. Use of the Uniflex endoprosthesis is preferable.
Tài liệu tham khảo
Barkov, A.A., and Movchan, K.N., Khirurgicheskoe lechenie posleoperatsionnykh gryzh (Surgical Treatment of Postoperative Hernias), Moscow: RBSFM, 1995.
Egiev, V.I., Nenatyazhnaya gernioplastika (Nonstrain Hernioplastics), Moscow: Medpraktika, 2002.
Grubnik, V.V., Losev, A.A., Bayazitov, N.R., and Parfent’ev, R.S., Sovremennye metody lecheniya bryushnykh gryzh (Modern Methods of Treatment of Abdominal Hernias), Kiev: Zdorov’ya, 2001.
Hebda, P.A., and Dohar, J.E., Transplanted Fetal Fibroblasts: Survival and Distribution over Time in Normal Adult Dermis Compared with Autogenic, Allogenic, and Xenogenic Adult Fibroblasts, Otolaryngol. Head Neck Surg., 1999, vol. 121, pp. 245–251.
Klinge, U., Anurov, M., and Banin, V., Functional and Morphological Results of Implantation of Polypropylene Nets for Closing Abdominal Front Wall Defects in the Experiment, in Sovremennye podkhody k razrabotke i klinicheskomu primeneniyu effektivnykh perevyazochnykh sredstv, shovnykh materialov i polimernykh implantatov. Materialy 4-i Mezhdunarod. koferentsii (Modern Approaches to the Development and Clinical Application of Effective Dressings, Suture Materials and Polymer Implants. Proc. 4th Int. Conf.), Moscow, 2001, pp. 162–163.
Romashin-Timanov, M.V., Ivanov, A.V., Gaiduk, S.S., and Kevelenov, P.A., The Use of Polypropylene Reticular Explants in Surgery of Postoperative Ventral Hernias in Patients with Diabetes, Vestn. Gerniol., Moscow, 2008, pp. 116–119.
Sedov, V.M., Gostevoy, A.A., Tarbaev, S.D., Gorelov, A.S., and Chukhlovin, A.B., Clinical Aspects of Bioinertness of Prostheses for Hernioplasty, in Materialy III Mezhdunarod. Khirurg. Kongressa “Nauchnye issledovaniya v realizatsii programmy ‘Zdorov’e naseleniya Rossii’” (Proc. III Int. Surgical Congr. Research Program “Public Health in Russia”), Moscow, 2008, pp. 59–60.
Smith, R.S., Smith, T.J., Blieden, T.M., and Phipps, R.P., Fibroblasts as Sentinel Cells. Synthesis of Chemokines and Regulation of Inflammation, Am. J. Pathol., 1997, vol. 151, pp. 317–322.
Sukovatykh, B.S., Netyaga, A.A., Zhukovskii, V.A., Valuiskaya, N.M., and Korovicheva, S.Yu., Modern Polymer Materials in Plastic Surgery of Postoperative and Recurrent Ventral Hernias, Kursk. Nauch.-Prakt. Vestnik “Chelovek i ego zdorov’e”, 2006, vol. 1, pp. 72–78.
Timoshin, A.D., Yurasov, A.V., and Shestakov, A.L., Khirurgicheskoe lechenie pakhovykh i posleoperatsionnykh gryzh bryushnoy stenki (Surgical Treatment of Inguinal and Postoperative Hernias of the Abdominal Wall), Moscow: Triada-X, 2003.
Zarivchatskii, M.F. and Yakovkin, V.F., Bol’shie i gigantskie posleoperatsionnye ventral’nye gryzhi (Large and Giant Postoperative Ventral Hernias), Perm’, 1996.
Zhebrovskii, V.V., Khirurgiya gryzh zhivota (Abdominal Hernia Surgery), Moscow: Meditsinskoe Informatsionnoe Agenstvo, 2005.