Comparative study of the treatment of 20–30 mm renal stones with miniaturized percutaneous nephrolithotomy and flexible ureterorenoscopy in obese patients

Springer Science and Business Media LLC - Tập 36 - Trang 1309-1314 - 2018
He-Qun Chen1, Zhi-Yong Chen1, Feng Zeng1, Yang Li1, Zhong-Qing Yang1, Cheng He1, Yao He1
1Department of Urology, Xiangya Hospital, Central South University, Changsha, China

Tóm tắt

To evaluate and compare flexible ureteroscopy (f-URS) and mini-percutaneous nephrolithotomy (mPNL) for 20–30 mm renal stones in obese patients regarding efficacy and safety. Between May 2011 and June 2017, 254 obese patients who had 20–30 mm kidney stone were consecutively included in the study; 106 patients underwent mPNL and 148 underwent f-URS by the same surgeon. The following parameters were retrospectively assessed: patient and stone characteristics, surgical details, perioperative outcomes, and stone-free rates (SFR). F-URS group was similar to mPNL group in terms of the mean duration of surgery (92.8 ± 26.1 vs 87.4 ± 31.5 min, P = 0.137) and the final SFR (89.1 vs 92.5%, P = 0.381). The f-URS group had significantly shorter postoperative stay (1.0 ± 0.8 vs 4.3 ± 1.7 days, P < 0.001) and lower postoperative complications (11.5 vs 26.4%, P = 0.002). However, the f-URS group had a lower SFR after first session (67.2 vs 87.4%, P < 0.001) and needed more number of procedures (1.5 ± 0.4 vs 1.3 ± 0.4, P < 0.001) than the mPNL group. MPNL has a higher efficacy (higher SFR after first session and lower number of procedures); however, f-URS offers advantages regarding safety (lower complication rate). Therefore, both options can be offered to obese patients with renal stones from 20 to 30 mm in size. Nevertheless, these results must be confirmed by further prospective randomized trials.

Tài liệu tham khảo

Wong YV, Cook P, Somani BK (2015) The association of metabolic syndrome and urolithiasis. Int J Endocrinol 2015:570674 Krzysztoszek J, Wierzejska E, Zielinska A (2015) Obesity. An analysis of epidemiological and prognostic research. Arch Med Sci 11:24–33 Türk C et al (2016) EAU Guidelines on interventional treatment for urolithiasis. Eur Urol 69:475–482 El-Assmy AM et al (2007) Outcome of percutaneous nephrolithotomy: effect of Body Mass Index. Eur Urol 52:199–204 Fuller A et al (2012) The CROES percutaneous nephrolithotomy global study: the influence of Body Mass Index on outcome. J Urol 188:138–144 Streeper NM et al (2016) Percutaneous nephrolithotomy in patients with BMI > 50: single surgeon outcomes and feasibility. Urology 87:33–39 Breda A et al (2008) Flexible ureteroscopy and laser lithotripsy for single intrarenal stones 2 cm or greater—is this the new frontier? J Urol 179:981–984 Takazawa R, Kitayama S, Tsujii T (2012) Successful outcome of flexible ureteroscopy with holmium laser lithotripsy for renal stones 2 cm or greater. Int J Urol 19:264–267 Cohen J, Cohen S, Grasso M (2013) Ureteropyeloscopic treatment of large, complex intrarenal and proximal ureteral calculi. BJU Int 111:127–131 Chen J et al (2014) Multiple tracts percutaneous nephrolithotomy assisted by LithoClast master in one session for staghorn calculi: report of 117 cases. Urolithiasis 42:165–169 Chen HQ, Zeng F, Qi L, Li Y (2013) Percutaneous nephrolithotomy in patients with scoliosis: our institutional experience. Urolithiasis 41:59–64 Chen H et al (2014) Percutaneous intrarenal cyst marsupialization and simultaneous nephrolithotomy in selected patients: killing two birds with one stone? Urology 84:1267–1271 Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213 Aboumarzouk OM et al (2012) Flexible ureteroscopy and laser lithotripsy for stones > 2 cm: a systematic review and meta-analysis. J Endourol 26:1257–1263 Palmero JL et al (2014) Results of retrograde intrarenal surgery in the treatment of renal stones greater than 2 cm. Actas Urol Esp 38:257–262 Aboumarzouk OM, Somani B, Monga M (2012) Safety and efficacy of ureteroscopic lithotripsy for stone disease in obese patients: a systematic review of the literature. BJU Int 110:374–380 Kamphuis GM et al (2015) Lessons learned from the CROES percutaneous nephrolithotomy global study. World J Urol 33:223–233 Zhou X et al (2017) Effect of obesity on outcomes of percutaneous nephrolithotomy in renal stone management: a systematic review and meta-analysis. Urol Int 98:382–390 Caskurlu T et al (2013) The impact of Body Mass Index on the outcomes of retrograde intrarenal stone surgery. Urology 81:517–521 Doizi S et al (2015) Comparative study of the treatment of renal stones with flexible ureterorenoscopy in normal weight, obese, and morbidly obese patients. Urology 85:38–44 Ishii H et al (2016) Outcomes of systematic review of ureteroscopy for stone disease in the obese and morbidly obese population. J Endourol 30:135–145 Ozgor F et al (2016) Comparison of miniaturized percutaneous nephrolithotomy and flexible ureterorenoscopy for the management of 10–20 mm renal stones in obese patients. World J Urol 34:1169–1173 Hyams ES, Shah O (2009) Percutaneous nephrostolithotomy versus flexible ureteroscopy/holmium laser lithotripsy: cost and outcome analysis. J Urol 182:1012–1017 Grasso M, Conlin M, Bagley D (1998) Retrograde ureteropyeloscopic treatment of 2 cm or greater upper urinary tract and minor staghorn calculi. J Urol 160:346–351 Riley JM, Stearman L, Troxel S (2009) Retrograde ureteroscopy for renal Stones larger than 2.5 cm. J Endourol 23:1395–1398