Comparative study of pathological changes in the mouse viscera in infection caused by two orthopoxviruses

Bulletin of Experimental Biology and Medicine - Tập 141 - Trang 448-452 - 2006
I. V. Vinogradov1, G. V. Kochneva1, E. M. Malkova1, S. N. Shchelkunov1, E. I. Ryabchikova1
1Vector State Research Center of Virology and Biotechnology, Novosibirsk

Tóm tắt

The mechanisms of infection development in intraperitoneal inoculation of mice by ectromelia virus strain K-1 and cowpox strain EP-2 were studied. Ultrastructural parameters of virus assembly and maturation are described. Differences in the types of cells replicating the viruses and in the type of visceral injuries were detected. The studies showed a local type of strain EP-2 cowpox infection and dissemination of ectromelia strain K-1.

Tài liệu tham khảo

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