Comparative study of assays detecting circulating immune complexes and specific antibodies in patients infected with Toxocara canis

Journal of Helminthology - Tập 61 Số 3 - Trang 196-202 - 1987
C. del Águila1, Carmen Cuéllar2, Soledad Fenoy2, J.L. Guillén2
1Departamento de Parasitología, Facultad de Farmacia, U.C.M., Madrid, Spain.
2Departamento de Parasitología, Facultad de Farmacia, U.C.M., 28040 Madrid, Spain

Tóm tắt

ABSTRACT

A sandwich ELISA method using previously described E/S antigen-specific monoclonal antibodies has been developed to detect circulating immune complexes in patients infected with Toxocara canis. This technique could be used for the study of the dynamics of the parasite-host relationship, as we believe the detection of immune complexes and/or soluble antigen to be an improvement over detection of antibodies only. In this parasitosis, antibodies may be present in residual levels for prolonged periods after active infection.

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