Common TMPRSS6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion

Barton, 2000, Intravenous iron dextran therapy in patients with iron deficiency and normal renal function who failed to respond to or did not tolerate oral iron supplementation, Am. J. Med., 109, 27, 10.1016/S0002-9343(00)00396-X Barton, 2010, Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients, BMC. Blood Disord., 10, 9, 10.1186/1471-2326-10-9 Barton, 2008, Thyroid-stimulating hormone and free thyroxine levels in persons with HFE C282Y homozygosity, a common hemochromatosis genotype: the HEIRS Study, Thyroid, 18, 831, 10.1089/thy.2008.0091 Benyamin, 2009, Common variants in TMPRSS6 are associated with iron status and erythrocyte volume, Nat. Genet., 41, 1173, 10.1038/ng.456 Beutler, 2010, Polymorphisms and mutations of human TMPRSS6 in iron deficiency anemia, Blood Cells Mol. Dis., 44, 16, 10.1016/j.bcmd.2009.09.001 Chambers, 2009, Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels, Nat. Genet., 41, 1170, 10.1038/ng.462 Crosby, 1976, Pica, JAMA, 235, 2765, 10.1001/jama.1976.03260510055032 Du, 2008, The serine protease TMPRSS6 is required to sense iron deficiency, Science, 320, 1088, 10.1126/science.1157121 Finberg, 2008, Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA), Nat. Genet., 40, 569, 10.1038/ng.130 Hooper, 2003, Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues, Biochem. J., 373, 689, 10.1042/bj20030390 Kemna, 2008, Regulation of hepcidin: insights from biochemical analyses on human serum samples, Blood Cells Mol. Dis., 40, 339, 10.1016/j.bcmd.2007.10.002 Kettaneh, 2005, Pica and food craving in patients with iron-deficiency anemia: a case–control study in France, Am. J. Med., 118, 185, 10.1016/j.amjmed.2004.07.050 Moore, 1994, Pica, iron deficiency, and the medical history, Am. J. Med., 97, 390, 10.1016/0002-9343(94)90309-3 Nai, 2011, TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals, Blood, 118, 4459, 10.1182/blood-2011-06-364034 Pasricha, 2011, Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors, Haematologica, 96, 1099, 10.3324/haematol.2010.037960 Reynolds, 1968, Pagophagia and iron deficiency anemia, Ann. Intern. Med., 69, 435, 10.7326/0003-4819-69-3-435 Traglia, 2011, Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations, J. Med. Genet., 48, 629, 10.1136/jmedgenet-2011-100061