Common Subtype of Small Renal Mass MR Imaging Characterisation: A Medical Center Experience in Taiwan

Springer Science and Business Media LLC - Tập 42 - Trang 87-97 - 2022
Ming-Cheng Liu1,2, Yi-Jui Liu2,3, Yen-Ting Lin1,4, Siu-Wan Hung1,5,6, Jyh-Wen Chai1, Si-Wa Chan7,8,9, Kun-Yuan Chiu10,11, Chih-Hao Chang12, Ya-Ling Tsou1
1Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan
2Ph.D. Program of Electrical and Communications Engineering, Feng Chia University, Taichung, Taiwan
3Department of Automatic Control Engineering, Feng Chia University. Taichung, Taiwan
4Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
5Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan
6School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan
7Department of Medical Imaging, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan
8School of Medicine, Tzu Chi University, Hualien, Taiwan
9Department of Medical Imaging Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan
10Division of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan
11Department of Applied Chemistry, National Chi Nan University, Nantou, Taiwan
12Nagoya University, Nagoya, Japan

Tóm tắt

Many studies have shown that multiparametric magnetic resonance imaging (MRI) may be helpful for differentiating malignant renal cell carcinomas (RCCs) from benign lesions. However, the key imaging characteristics that differ between malignant and benign tumors still require further discussion. We analyzed 60 adult patients diagnosed with 72 small renal masses (SRMs) who received preoperative MRI from 2014 to 2019 at a hospital in Taiwan. The MRI features included conventional MRI parameters, diffusion-weighted imaging (DWI) data, and dynamic contrast-enhanced (DCE) patterns, which were documented and compared among the four common subtypes: clear cell RCC (ccRCC), papillary RCC (pRCC), angiomyolipoma (AML) and other types of RCC. The apparent diffusion coefficient (ADC) values of high- and low-grade RCCs were also analyzed. The results show that ccRCC had higher T2-weighted signal intensity than the other three subgroups, a higher arterial wash-in index (AWI) and ADC value than AML and pRCC, and manifested a plateau (n = 9, 25%) or washout (n = 27, 75%) enhancement pattern. AMLs exhibited more intravoxel fat than the other three subtype groups, and half of the AMLs (6 in 12) contained bulk fat. pRCC demonstrated a more progressive (n = 3, 60%) enhancement pattern than the other three subgroups. The ADC value of high-grade RCCs was significantly lower than that of low-grade RCCs. These findings may indicate that multiparametric MRI is useful in differentiating among four common pathological types of SRMs, and the ADC value may be helpful in evaluating the histological grade of malignancy.

Tài liệu tham khảo

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Tập 42

87-97

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