Commensal bacteria stimulate antitumor responses via T cell cross-reactivity

JCI insight - Tập 5 Số 8 - 2020
Catherine Bessell1, Ariel Isser2, Jonathan J. Havel3, Sangyun Lee4, David R. Bell4, John W. Hickey2, Worarat Chaisawangwong5, Joan Glick Bieler5, Raghvendra M. Srivastava3, Fengshen Kuo3, Tanaya A. Purohit3, Ruhong Zhou4,6, Timothy A. Chan7,3,8, Jonathan P. Schneck5,1,9
1Graduate Program in Immunology and
2Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
3Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA
4Computational Biology Center, IBM Thomas J. Watson Research Center, Yorktown Heights, New York, USA.
5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
6Department of Chemistry, Columbia University, New York, New York, USA
7Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA.
8Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
9Institute of Cellular Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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10.1126/science.aaa1348

10.1038/nature13988

10.1038/nm.4051

10.1038/nature24473

10.1038/nature24462

10.1126/science.aan3706

10.1126/science.aan4236

10.1126/science.1240527

10.1126/science.1240537

10.4049/jimmunol.1003937

10.1016/j.cell.2007.01.048

10.1021/acsnano.5b02829

10.1126/science.aac4255

10.1002/iid3.35

10.1158/0008-5472.CAN-03-3259

10.1158/2326-6066.CIR-17-0114

10.4049/jimmunol.174.6.3416

10.1126/science.aao3290

10.1126/science.aav3487

10.1016/j.chom.2019.05.003

10.1038/s41586-019-0878-z

10.1038/s41571-018-0006-2

10.1126/science.aar6918

10.1128/AEM.71.5.2318-2324.2005

Humphrey, 1996, VMD: visual molecular dynamics, J Mol Graph, 14, 33, 10.1016/0263-7855(96)00018-5

Abraham, 2015, GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers, SoftwareX, 1, 19, 10.1016/j.softx.2015.06.001

10.1021/ct300400x

10.1063/1.445869

10.1063/1.464397

10.1002/(SICI)1096-987X(199709)18:12<1463::AID-JCC4>3.0.CO;2-H

10.1063/1.447334

10.1063/1.448118

10.1021/acs.jcim.9b00558

10.1002/jcc.23804

10.1016/0009-2614(94)00397-1

Xia, 2014, The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function, Sci Rep, 4, 10.1038/srep04087

Hölzemer, 2015, Selection of an HLA-C*03:04-restricted HIV-1 p24 gag sequence variant is associated with viral escape from KIR2DL3+ natural killer cells: data from an observational cohort in South Africa, PLoS Med, 12, 10.1371/journal.pmed.1001900

10.1126/science.aao4572

10.1073/pnas.1718659115

10.1063/1.1749657

10.1063/1.461148

Russ, 2012, Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection, Front Immunol, 3, 10.3389/fimmu.2012.00371