Rautava S, Kalliomaki M, Isolauri E: New therapeutic strategy for combating the increasing burden of allergic disease: Probiotics-A Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota (NAMI) Research Group report. J Allergy Clin Immunol 2005, 116:31–37.
Zhang G, Ghosh S: Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity. J Clin Invest 2001, 107:13–19.
Schnare M, Barton GM, Holt AC, et al.: Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001, 2:947–950.
Kaisho T, Akira S: Toll-like receptor function and signaling. J Allergy Clin Immunol 2006, 117:979–987.
Akira S, Uematsu S, Takeuchi O: Pathogen recognition and innate immunity. Cell 2006, 124:783–801.
Cario E: Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2. Gut 2005, 54:1182–1193.
Hausmann M, Kiessling S, Mestermann S, et al.: Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. Gastroenterology 2002, 122:1987–2000.
Hart AL, Al-Hassi HO, Rigby RJ, et al.: Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Gastroenterology 2005, 129:50–65.
Kawai T, Akira S: TLR signaling. Semin Immunol 2007, 19:24–32.
Hayden MS, Ghosh S: Signaling to NF-kappaB. Genes Dev 2004, 18:2195–2224.
O’Neill LA, Fitzgerald KA, Bowie AG: The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol 2003, 24:286–290.
Otte JM, Cario E, Podolsky DK: Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 2004, 126:1054–1070.
Haller D, Jobin C: Interaction between resident luminal bacteria and the host: can a healthy relationship turn sour? J Pediatr Gastroenterol Nutr 2004, 38:123–136.
Ogura Y, Bonen DK, Inohara N, et al.: A frameshift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature 2001, 411:603–606.
Girardin SE, Boneca IG, Carneiro LA, et al.: Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 2003, 300:1584–1587.
Chin AI, Dempsey PW, Bruhn K, et al.: Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 2002, 416:190–194.
Eder W, Klimecki W, Yu L, et al.: Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol 2004, 113:482–488.
Ley RE, Peterson DA, Gordon JI: Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell. 2006, 124:837–848.
Tannock GW: What immunologists should know about bacterial communities of the human bowel. Semin Immunol 2006, 19:94–105
Matsumiya Y, Kato N, Watanabe K, Kato H: Molecular epidemiological study of vertical transmission of vaginal Lactobacillus species from mothers to newborn infants in Japanese, by arbitrarily primed polymerase chain reaction. J Infect Chemother 2002, 8:43–49.
Gronlund MM, Lehtonen OP, Eerola E, Kero P: Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr 1999, 28:19–25.
Harmsen HJ, Wildeboer-Veloo AC, Raangs GC, et al.: Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J Pediatr Gastroenterol Nutr 2000, 30:61–67.
Bennet R, Eriksson M, Nord CE, Zetterstrom R: Fecal bacterial microflora of newborn infants during intensive care management and treatment with five antibiotic regimens. Pediatr Infect Dis 1986, 5:533–539.
de la Cochetiere MF, Piloquet H, des Robert C, et al.: Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of Clostridium. Pediatr Res 2004, 56:366–370.
Rautava S: Potential uses of probiotics in the neonate. Semin Fetal Neonatal Med 2007, 12:45–53.
Hooper LV: Bacterial contributions to mammalian gut development. Trends Microbiol 2004, 12:129–134.
Hooper LV, Wong MH, Thelin A, et al.: Molecular analysis of commensal host-microbial relationships in the intestine. Science 2001, 291:881–884.
Bron PA, Marco M, Hoffer SM, et al.: Genetic characterization of the bile salt response in Lactobacillus plantarum and analysis of responsive promoters in vitro and in situ in the gastrointestinal tract. J Bacteriol 2004, 186:7829–7835.
Sudo N, Sawamura S, Tanaka K, et al.: The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 1997, 159:1739–1745.
Bashir ME, Louie S, Shi HN, et al.: Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. J Immunol 2004, 172:6978–6987.
Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL: An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005, 122:107–118.
Liu PT, Stenger S, Li H, et al.: Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006, 311:1770–1773.
Lee JY, Zhao L, Youn HS, et al.: Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. J Biol Chem 2004, 279:16971–16979.
Ruiz PA, Hoffmann M, Szcesny S, et al.: Innate mechanisms for Bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats. Immunology 2005, 115:441–450.
Savidge TC, Newman PG, Pan WH, et al.: Lipopolysaccharide-induced human enterocyte tolerance to cytokine-mediated interleukin-8 production may occur independently of TLR-4/MD-2 signaling. Pediatr Res 2006, 59:89–95.
Lee J, Mo JH, Katakura K, et al.: Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 2006, 8:1327–1336.
Melmed G, Thomas LS, Lee N, et al.: Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol 2003, 170:1406–1415.
Gewirtz AT, Navas TA, Lyons S, et al.: Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol 2001, 167:1882–1885.
Malin M, Isolauri E, Pikkarainen P, et al.: Enhanced absorption of macromolecules. A secondary factor in Crohn’s disease. Dig Dis Sci 1996, 41:1423–1428.
Collier-Hyams LS, Zeng H, Sun J, et al.: Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway. J Immunol 2002, 169:2846–2850.
Neish AS, Gewirtz AT, Zeng H, et al.: Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science 2000, 289:1560–1563.
Kelly D, Campbell JI, King TP, et al.: Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol Jan 2004, 5:104–112.
Kanneganti TD, Lamkanfi M, Kim YG, et al.: Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 2007, 26:433–443.
Nenci A, Becker C, Wullaert A, et al.: Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 2007, 446:557–561.
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, et al.: Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004, 118:229–241.
Rescigno M, Urbano M, Valzasina B, et al.: Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol 2001, 2:361–367.
Michelsen KS, Aicher A, Mohaupt M, et al.: The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2. J Biol Chem 2001, 276:25680–25686.
Turnbull EL, Yrlid U, Jenkins CD, Macpherson GG: Intestinal dendritic cell subsets: differential effects of systemic TLR4 stimulation on migratory fate and activation in vivo. J Immunol 2005, 174:1374–1384.
An H, Yu Y, Zhang M, et al.: Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology 2002, 106:38–45.
Macpherson AJ, Uhr T: Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 2004, 303:1662–1665.
Niess JH, Reinecker HC: Dendritic cells: the commanders-inchief of mucosal immune defenses. Curr Opin Gastroenterol 2006, 22:354–360.
Uematsu S, Jang MH, Chevrier N, et al.: Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat Immunol 2006, 7:868–874.
Wang Q, McLoughlin RM, Cobb BA, et al.: A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2. J Exp Med 2006, 203:2853–2863.
Moseman EA, Liang X, Dawson AJ, et al.: Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J Immunol 2004, 173:4433–4442.
Pasare C, Medzhitov R: Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003, 299:1033–1036.