Combining dynamic contrast enhanced magnetic resonance imaging and microvessel density to assess the angiogenesis after PEI in a rabbit VX2 liver tumor model

Ferlay, 2010, Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008, Int J Cancer, 127, 2893, 10.1002/ijc.25516 Livraghi, 1992, Percutaneous ethanol injection in the treatment of hepatocellular carcinoma in cirrhosis. A study on 207 patients, Cancer, 69, 925, 10.1002/1097-0142(19920215)69:4<925::AID-CNCR2820690415>3.0.CO;2-G Lencioni, 2010, Loco-regional interventional treatment of hepatocellular carcinoma: techniques, outcomes, and future prospects, Transpl Int, 23, 698, 10.1111/j.1432-2277.2010.01109.x Lee, 1995, Percutaneous ethanol injection for the treatment of hepatic tumors: indications, mechanism of action, technique, and efficacy, AJR Am J Roentgenol, 164, 215, 10.2214/ajr.164.1.7998542 Zou, 2013, Ultrasound-guided percutaneous laser and ethanol ablation of rabbit VX2 liver tumors, Acta Radiol, 54, 181, 10.1258/ar.2012.110723 Lin, 2014, Combining radiofrequency ablation and ethanol injection may achieve comparable long-term outcomes in larger hepatocellular carcinoma (3.1-4 cm) and in high-risk locations, Kaohsiung J Med Sci, 30, 396, 10.1016/j.kjms.2014.04.006 Folkman, 2002, Role of angiogenesis in tumor growth and metastasis, Semin Oncol, 29, 15, 10.1053/sonc.2002.37263 Iagaru, 2013, Imaging tumor angiogenesis: the road to clinical utility, AJR Am J Roentgenol, 201, W183, 10.2214/AJR.12.8568 Shao, 2013, Dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging noninvasive evaluation of vascular disrupting treatment on rabbit liver tumors, PLoS One, 8, e82649, 10.1371/journal.pone.0082649 Yang, 2014, In vivo assessment of the vascular disrupting effect of M410 by DCE-MRI biomarker in a rabbit model of liver tumor, Oncol Rep, 32, 709, 10.3892/or.2014.3230 Kim, 2013, Vascular disrupting effect of CKD-516: preclinical study using DCE-MRI, Invest New Drugs, 31, 1097, 10.1007/s10637-012-9915-6 Messiou, 2012, Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity, Radiology, 265, 426, 10.1148/radiol.12112565 Thng, 2010, Perfusion magnetic resonance imaging of the liver, World J Gastroenterol, 16, 1598, 10.3748/wjg.v16.i13.1598 Sato, 2011, Four-dimensional transcatheter intraarterial perfusion MRI monitoring of radiofrequency ablation of rabbit VX2 liver tumors, J Magn Reson Imaging, 34, 563, 10.1002/jmri.22644 Wang, 2008, Four-dimensional transcatheter intraarterial perfusion (TRIP)-MRI for monitoring liver tumor embolization in VX2 rabbits, Magn Reson Med, 60, 970, 10.1002/mrm.21678 Hoekstra, 2013, Enhanced tumor growth after portal vein embolization in a rabbit tumor model, J Surg Res, 180, 89, 10.1016/j.jss.2012.10.032 Sonoda, 2011, Time-course studies of implanted rabbit VX2 liver tumors to identify the appropriate time for starting hepatic arterial embolization in animal models, Oncol-Basel, 80, 92, 10.1159/000328763 Weidner, 1995, Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors, Breast Cancer Res Treat, 36, 169, 10.1007/BF00666038 Kerbel, 2008, Tumor angiogenesis, N Engl J Med, 358, 2039, 10.1056/NEJMra0706596 Liu, 2012, Effects of transcatheter arterial chemoembolization with pingyangmycin-lipiodol emulsion on VX2 liver tumors in rabbits, Zhonghua Gan Zang Bing Za Zhi, 20, 611 Nielsen, 2012, Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) in Preclinical Studies of Antivascular Treatments, Pharmaceutics, 4, 563, 10.3390/pharmaceutics4040563 Yeo, 2015, Correlation of dynamic contrast-enhanced MRI perfusion parameters with angiogenesis and biologic aggressiveness of rectal cancer: Preliminary results, J Magn Reson Imaging, 41, 474, 10.1002/jmri.24541 Tuncbilek, 2009, Value of dynamic contrast-enhanced MRI and correlation with tumor angiogenesis in bladder cancer, AJR Am J Roentgenol, 192, 949, 10.2214/AJR.08.1332 Thomassin-Naggara, 2008, Epithelial ovarian tumors: value of dynamic contrast-enhanced MR imaging and correlation with tumor angiogenesis, Radiology, 248, 148, 10.1148/radiol.2481071120 Hirashima, 2012, Pharmacokinetic parameters from 3-Tesla DCE-MRI as surrogate biomarkers of antitumor effects of bevacizumab plus FOLFIRI in colorectal cancer with liver metastasis, Int J Cancer, 130, 2359, 10.1002/ijc.26282 Tofts, 1999, Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols, J Magn Reson Imaging, 10, 223, 10.1002/(SICI)1522-2586(199909)10:3<223::AID-JMRI2>3.0.CO;2-S Liao, 2004, Angiogenesis in rabbit hepatic tumor after transcatheter arterial embolization, World J Gastroenterol, 10, 1885, 10.3748/wjg.v10.i13.1885 Gupta, 2006, Effect of transcatheter hepatic arterial embolization on angiogenesis in an animal model, Invest Radiol, 41, 516, 10.1097/01.rli.0000209663.00629.8a Qian, 2014, Diffusion-weighted magnetic resonance imaging to evaluate microvascular density after transarterial embolization ablation in a rabbit VX2 liver tumor model, Magn Reson Imaging, 32, 1052, 10.1016/j.mri.2014.05.011 Gadaleta, 2011, Trans-arterial chemoembolization as a therapy for liver tumours: New clinical developments and suggestions for combination with angiogenesis inhibitors, Crit Rev Oncol Hematol, 80, 40, 10.1016/j.critrevonc.2010.10.005 Giesel, 2008, Pharmacokinetic analysis of malignant pleural mesothelioma-initial results of tumor microcirculation and its correlation to microvessel density (CD-34), Acad Radiol, 15, 563, 10.1016/j.acra.2007.12.014 Oshida, 2005, Pharmacokinetic analysis of ductal carcinoma in situ of the breast using dynamic MR mammography, Eur Radiol, 15, 1353, 10.1007/s00330-005-2661-9 Kim, 2013, Perfusion parameters of dynamic contrast-enhanced magnetic resonance imaging in patients with rectal cancer: correlation with microvascular density and vascular endothelial growth factor expression, Korean J Radiol, 14, 878, 10.3348/kjr.2013.14.6.878 Ahn, 2011, Correlations of 3T DCE-MRI quantitative parameters with microvessel density in a human-colorectal-cancer xenograft mouse model, Korean J Radiol, 12, 722, 10.3348/kjr.2011.12.6.722 Robinson, 2003, Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry, J Magn Reson Imaging, 17, 445, 10.1002/jmri.10274 Hylton, 2006, Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker, J Clin Oncol, 24, 3293, 10.1200/JCO.2006.06.8080