Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer

JCI insight - Tập 3 Số 20 - 2018
Heather Kinkead1, Alexander C. Hopkins1, Eric R. Lutz1, Annie A. Wu1, Mark Yarchoan1, Kayla Cruz1, Skylar Woolman1, Teena Vithayathil1, Laura Hix Glickman2,3, Chudi Ndubaku3, Sarah M. McWhirter3, Thomas W. Dubensky3,4, Todd D. Armstrong1, Elizabeth M. Jaffee1, Neeha Zaidi1
1Sidney Kimmel Comprehensive Cancer Center, Skip Viragh Center for Pancreatic Cancer, The Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
2Actym Therapeutics Inc., Berkeley, California, USA.
3Aduro Biotechnologies Inc., Berkeley, California, USA.
4Tempest Therapeutics, San Francisco, California, USA.

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