Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission
Tài liệu tham khảo
Arlotta, 2005, Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo, Neuron, 45, 207, 10.1016/j.neuron.2004.12.036
BrainSpan (2011). BrainSpan: Atlas of the Developing Human Brain. http://www.brainspan.org/.
Brennand, 2015, Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia, Mol. Psychiatry, 20, 361, 10.1038/mp.2014.22
Chambers, 2009, Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling, Nat. Biotechnol., 27, 275, 10.1038/nbt.1529
Darmanis, 2015, A survey of human brain transcriptome diversity at the single cell level, Proc. Natl. Acad. Sci. USA, 112, 7285, 10.1073/pnas.1507125112
Di Giorgio, 2008, Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation, Cell Stem Cell, 3, 637, 10.1016/j.stem.2008.09.017
Edgar, 2002, Gene Expression Omnibus: NCBI gene expression and hybridization array data repository, Nucleic Acids Res., 30, 207, 10.1093/nar/30.1.207
Epi, 2015, A roadmap for precision medicine in the epilepsies, Lancet Neurol., 14, 1219, 10.1016/S1474-4422(15)00199-4
Eroglu, 2010, Regulation of synaptic connectivity by glia, Nature, 468, 223, 10.1038/nature09612
Espuny-Camacho, 2013, Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo, Neuron, 77, 440, 10.1016/j.neuron.2012.12.011
Gupta, 2013, NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons, Neurosci. Lett., 543, 95, 10.1016/j.neulet.2013.03.010
Ho, 2015, From “directed differentiation” to “neuronal induction”: modeling neuropsychiatric disease, Biomark. Insights, 10, 31
Ip, 2010, Investigating gradients of gene expression involved in early human cortical development, J. Anat., 217, 300
Kirwan, 2015, Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro, Development, 142, 3178, 10.1242/dev.123851
Lake, 2016, Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain, Science, 352, 1586, 10.1126/science.aaf1204
Lein, 2007, Genome-wide atlas of gene expression in the adult mouse brain, Nature, 445, 168, 10.1038/nature05453
Lewis, 2003, Altered cortical glutamate neurotransmission in schizophrenia: evidence from morphological studies of pyramidal neurons, Ann. N Y Acad. Sci., 1003, 102, 10.1196/annals.1300.007
Maroof, 2013, Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells, Cell Stem Cell, 12, 559, 10.1016/j.stem.2013.04.008
Mertens, 2016, Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience, Nat. Rev. Neurosci., 17, 424, 10.1038/nrn.2016.46
Miller, 2014, Transcriptional landscape of the prenatal human brain, Nature, 508, 199, 10.1038/nature13185
Oswald, 2008, Maturation of intrinsic and synaptic properties of layer 2/3 pyramidal neurons in mouse auditory cortex, J. Neurophysiol., 99, 2998, 10.1152/jn.01160.2007
Paşca, 2015, Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture, Nat. Methods, 12, 671, 10.1038/nmeth.3415
Pfrieger, 2009, Roles of glial cells in synapse development, Cell. Mol. Life Sci., 66, 2037, 10.1007/s00018-009-0005-7
Picelli, 2013, Smart-seq2 for sensitive full-length transcriptome profiling in single cells, Nat. Methods, 10, 1096, 10.1038/nmeth.2639
Picelli, 2014, Full-length RNA-seq from single cells using Smart-seq2, Nat. Protoc., 9, 171, 10.1038/nprot.2014.006
Pollen, 2014, Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex, Nat. Biotechnol., 32, 1053, 10.1038/nbt.2967
Saito, 2011, Neocortical layer formation of human developing brains and lissencephalies: consideration of layer-specific marker expression, Cereb. Cortex, 21, 588, 10.1093/cercor/bhq125
Sanders, 2015, Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci, Neuron, 87, 1215, 10.1016/j.neuron.2015.09.016
2014, Biological insights from 108 schizophrenia-associated genetic loci, Nature, 511, 421, 10.1038/nature13595
Shcheglovitov, 2013, SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients, Nature, 503, 267, 10.1038/nature12618
Son, 2011, Conversion of mouse and human fibroblasts into functional spinal motor neurons, Cell Stem Cell, 9, 205, 10.1016/j.stem.2011.07.014
Spitzer, 1994, Spontaneous Ca2+ spikes and waves in embryonic neurons: signaling systems for differentiation, Trends Neurosci., 17, 115, 10.1016/0166-2236(94)90120-1
Tang, 2013, Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells, Stem Cell Res. (Amst.), 11, 743, 10.1016/j.scr.2013.05.002
Tao, 2016, Neural Subtype Specification from Human Pluripotent Stem Cells, Cell Stem Cell, 19, 573, 10.1016/j.stem.2016.10.015
Tasic, 2016, Adult mouse cortical cell taxonomy revealed by single cell transcriptomics, Nat. Neurosci., 19, 335, 10.1038/nn.4216
Traynelis, 2010, Glutamate receptor ion channels: structure, regulation, and function, Pharmacol. Rev., 62, 405, 10.1124/pr.109.002451
Treutlein, 2016, Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq, Nature, 534, 391, 10.1038/nature18323
Vierbuchen, 2010, Direct conversion of fibroblasts to functional neurons by defined factors, Nature, 463, 1035, 10.1038/nature08797
Wang, 2013, Distribution of CaMKIIα expression in the brain in vivo, studied by CaMKIIα-GFP mice, Brain Res., 1518, 9, 10.1016/j.brainres.2013.04.042
Yamamoto, 2015, Specific Roles of NMDA Receptor Subunits in Mental Disorders, Curr. Mol. Med., 15, 193, 10.2174/1566524015666150330142807
Yao, 2017, A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development, Cell Stem Cell, 20, 120, 10.1016/j.stem.2016.09.011
Yuan, 2015, Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases, Mol. Pharmacol., 88, 203, 10.1124/mol.115.097998
Zhang, 2013, Rapid single-step induction of functional neurons from human pluripotent stem cells, Neuron, 78, 785, 10.1016/j.neuron.2013.05.029
