Combination of EPA with Carotenoids and Polyphenol Synergistically Attenuated the Transformation of Microglia to M1 Phenotype Via Inhibition of NF-κB
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Anderle, P., Farmer, P., Berger, A., & Roberts, M. A. (2004). Nutrigenomic approach to understanding the mechanisms by which dietary long-chain fatty acids induce gene signals and control mechanisms involved in carcinogenesis. Nutrition, 20, 103–108.
Arun, P., Brown, M., Ehsanian, R., Chen, Z., & Waes, C. V. (2009). Nuclear NF-κB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer. Clinical Cancer Research, 15(19), 5974–5984.
Aruoma, O., Halliwell, B., Aeschbach, R., & Loligers, J. (1992). Antioxidant and pro-oxidant properties of active rosemary constituents: Carnosol and carnosic acid. Xenobiotica, 22, 257–268.
Azad, N., Rasoolijazi, H., Joghataie, M. T., & Soleimani, S. (2011). Neuroprotective effects of carnosic acid in an experimental model of Alzheimer’s disease in rats. Cell Journal, 13, 39–44.
Barnham, K., Masters, C., & Bush, A. (2004). Neurodegenerative diseases and oxidative stress. Nature Reviews Drug Discovery, 3, 205–214.
Bozic, I., Savic, D., Laketa, D., Bjelobaba, I., Milenkovic, I., Pekovic, S., et al. (2015). Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia. PLoS ONE, 10, 118372–118395.
Britton, G. (1995). Structure and properties of carotenoids in relation to function. The FASEB Journal, 9, 1551–1558.
Calder, P. C. (2012a). Long-chain fatty acids and inflammation. Proceedings of the Nutrition Society, 71(2), 284–289.
Calder, P. C. (2012b). Mechanisms of action of (n-3) fatty acids. Journal of Nutrition, 142, 592S–599S.
Chen, K., Huang, J., Gong, W., Zhang, L., Yu, P., & Wang, J. M. (2006). CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system. Cellular & Molecular Immunology, 3(3), 163–169.
Chu, A. J., Walton, M. A., Prasad, J. K., & Seto, A. (1999). Blockade by polyunsaturated n-3 fatty acids of endotoxin-induced monocytic tissue factor activation is mediated by the depressed receptor expression in THP-1 cells. Journal of Surgical Research, 87, 217–224.
Chuang, D. Y., Simonyi, A., Kotzbauer, P. T., Gu, Z., & Sun, G. Y. (2015). Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway. Journal of Neuroinflammation, 12, 199.
Cianciulli, A., Salvatore, R., Porro, C., Trotta, T., & Panaro, M. A. (2016). Folic acid is able to polarize the inflammatory response in LPS activated microglia by regulating multiple signaling pathways. Mediators of Inflammation, 2016, 5240127.
Clinton, S. (1998). Lycopene: Chemistry, biology, and implications for human health and disease. Nutrition Reviews, 56, 35–51.
Colton, C., & Wilcock, D. M. (2010). Assessing activation states in microglia. CNS & Neurological Disorders: Drug Targets, 9, 174–191.
Conquer, J. A., Tierney, M. C., Zecevic, J., Bettger, W. J., & Fisher, R. H. (2000). Fatty acid analysis of blood plasma of patients with Alzheimer’s disease, other types of dementia, and cognitive impairment. Lipids, 35(12), 1305–1312.
Corsi, L., Dongmo, B. M., & Avallone, R. (2015). Supplementation of omega 3 fatty acids improves oxidative stress in activated BV2 microglial cell line. International Journal of Food Sciences and Nutrition, 66, 293–299.
da Silva, T. M., Munhoz, R. P., Alvarez, C., Naliwaiko, K., Kiss, A., Andreatini, R., et al. (2008). Depression in Parkinson’s disease: A double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation. Journal of Affective Disorders, 111, 351–359.
Doolaege, E. H., Raes, K., De Vos, F., Verhe, R., & De Smet, S. (2011). Absorption, distribution and elimination of carnosic acid, a natural antioxidant from Rosmarinus officinalis, in rats. Plant Foods for Human Nutrition, 66, 196–202.
Dyall, S. C. (2015). Long-chain omega-3 fatty acids and the brain: A review of the independent and shared effects of EPA, DPA and DHA. Front Aging Neurosci, 7, 52–67.
Eilander, A., Hundscheid, D. C., Osendarp, S. J., Transler, C., & Zock, P. L. (2007). Effects of n-3 long chain polyunsaturated fatty acid supplementation on visual and cognitive development throughout childhood: A review of human studies. Prostaglandins Leukotrienes and Essential Fatty Acids, 76, 189–203.
Feart, C., Peuchant, E., Letenneur, L., Samieri, C., Montagnier, D., Fourrier-Reglat, A., et al. (2008). Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: Data from the Bordeaux sample of the Three-City Study. American Journal of Clinical Nutrition, 87, 1156–1162.
Garcia-Alonso, F. J., Jorge-Vidal, V., Ros, G., & Periago, M. J. (2012). Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women. European Journal of Nutrition, 51, 415–424.
Hadad, N., & Levy, R. (2012). The synergistic anti-inflammatory effects of lycopene, lutein, β-carotene, and carnosic acid combinations via redox-based inhibition of NF-κB signaling. Free Radical Biology and Medicine, 53(7), 1381–1391.
Hazan, I., Dana, R., Granot, Y., & Levy, R. (1997). Cytosolic phospholipase A2 and its mode of activation in human neutrophils by opsonized zymosan: Correlation between 42/44 kDa mitogen-activated protein kinase, cytosolic phospholipase A2 and NADPH oxidase. Biochemical Journal, 326, 867–876.
Hazan-Eitan, Z., Weinstein, Y., Hadad, N., Konforty, A., & Levy, R. (2006). Induction of Fc gammaRIIA expression in myeloid PLB cells during differentiation depends on cytosolic phospholipase A2 activity and is regulated via activation of CREB by PGE2. Blood, 108, 1758–1766.
Hazan-Halevy, I., & Levy, R. (2000). Activation of cytosolic phospholipase A2 by opsonized zymosan in human neutrophils requires both ERK and p38 MAP-kinase. Advances in Experimental Medicine and Biology, 479, 115–123.
Itakura, H., Yokoyama, M., Matsuzaki, M., Saito, Y., Origasa, H., Ishikawa, Y., et al. (2011). Relationships between plasma fatty acid composition and coronary artery disease. Journal of Atherosclerosis and Thrombosis, 18, 99–107.
Jack, C., Ruffini, F., Bar-Or, A., & Antel, J. P. (2005). Microglia and multiple sclerosis. Journal of Neuroscience Research, 81, 363–373.
Johnson, E. J. (2014). Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan. Nutrition Reviews, 72, 605–612.
Kohman, R. A. (2012). Aging microglia: Relevance to cognition and neural plasticity. Methods in Molecular Biology, 934, 193–218.
Koscso, B., Csoka, B., Selmeczy, Z., Himer, L., Pacher, P., Virag, L., et al. (2012). Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process. The Journal of Immunology, 188(1), 445–453.
Kucuk, O., Sarkar, F., Sakr, W., Djuric, Z., Pollak, M., Khachik, F., et al. (2001). Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiology, Biomarkers and Prevention, 10, 861–868.
Kurtys, E., Eisel, U. L., Verkuyl, J. M., Broersen, L. M., Dierckx, R. A., & de Vries, E. F. (2016). The combination of vitamins and omega-3 fatty acids has an enhanced anti-inflammatory effect on microglia. Neurochemistry International, 99, 206–214.
Lee, J. Y., Plakidas, A., Lee, W. H., Heikkinen, A., Chanmugam, P., Bray, G., et al. (2003a). Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition by n-3 polyunsaturated fatty acids. Journal of Lipid Research, 44, 479–486.
Lee, A., Sung, S., Kim, Y., & Kim, S. (2003b). Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-α and COX-2 expression by sauchinone effects on I-κBα phosphorylation, C/EBP and AP-1 activation. British Journal of Pharmacology, 139, 11–20.
Libermann, T. A., & Baltimore, D. (1990). Activation of interleukin-6 gene expression through the NF-κ B transcription factor. Molecular and Cellular Biology, 10, 2327–2334.
Lin, P. Y., Chiu, C. C., Huang, S. Y., & Su, K. P. (2012). A meta-analytic review of polyunsaturated fatty acid compositions in dementia. Journal of Clinical Psychiatry, 73, 1245–1254.
Lin, H. Y., Huang, B. R., Yeh, W. L., Lee, C. H., Huang, S. S., Lai, C. H., et al. (2014). Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways. Neurobiology of Aging, 35, 191–202.
Lobo-Silva, D., Carriche, G. M., Castro, A. G., Roque, S., & Saraiva, M. (2016). Balancing the immune response in the brain: IL-10 and its regulation. Journal of Neuroinflammation, 13, 297–307.
Luo, X. G., Ding, J. Q., & Chen, S. D. (2010). Microglia in the aging brain: Relevance to neurodegeneration. Molecular Neurodegeneration, 5, 12–21.
Malada-Edelstein, Y. F., Hadad, N., & Levy, R. (2017). Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia. Journal of Neuroinflammation, 14, 33–49.
Mascio, P. D., Kaiser, S., & Sies, H. (1989). Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of Biochemistry and Biophysics, 274, 532–538.
Mazereeuw, G., Lanctot, K. L., Chau, S. A., Swardfager, W., & Herrmann, N. (2012). Effects of omega-3 fatty acids on cognitive performance: A meta-analysis. Neurobiology of Aging, 33(1482), e17–e1429.
Mengoni, E., Vichera, G., Rigano, L., Rodriguez-Puebla, M., Galliano, S., Cafferata, E., et al. (2010). Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L. Fitoterapia, 82, 414–421.
Moon, D. O., Kim, K. C., Jin, C. Y., Han, M. H., Park, C., Lee, K. J., et al. (2007). Inhibitory effects of eicosapentaenoic acid on lipopolysaccharide-induced activation in BV2 microglia. International Immunopharmacology, 7, 222–229.
Nakanishi, A., & Tsukamoto, I. (2015). n-3 polyunsaturated fatty acids stimulate osteoclastogenesis through PPARγ-mediated enhancement of c-Fos expression, and suppress osteoclastogenesis through PPARγ-dependent inhibition of NFkB activation. Journal of Nutritional Biochemistry, 26, 1317–1327.
Nguyen, V. T., & Benveniste, E. N. (2002). Critical role of tumor necrosis factor-α and NF-κ B in interferon-γ-induced CD40 expression in microglia/macrophages. Journal of Biological Chemistry, 277, 13796–13803.
Offord, E., Mace, K., Ruffieux, C., Malnoe, A., & Pfeifer, A. (1995). Rosemary components inhibit benzo[a]pyrene-induced genotoxicity in human bronchial cells. Carcinogenesis, 16, 2057–2062.
Pantano, C., Reynaert, N., Vliet, A. V. D., & Janssen-Heininger, Y. (2006). Redox-sensitive kinases of the nuclear factor-κB signaling pathway. Antioxidants & Redox Signaling, 8, 1791–1806.
Parker, G., Gibson, N. A., Brotchie, H., Heruc, G., Rees, A. M., & Hadzi-Pavlovic, D. (2006). Omega-3 fatty acids and mood disorders. American Journal of Psychiatry, 163, 969–978.
Perry, V. H., Nicoll, J. A., & Holmes, C. (2010). Microglia in neurodegenerative disease. Nature Reviews Neurology, 6(4), 193–201.
Rafi, M., Yadav, P., & Reyes, M. (2007). Lycopene inhibits LPS-induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells. Journal of Food Science, 72, S069–S074.
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996). Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine, 20(7), 933–956.
Romo Vaquero, M., Garcia Villalba, R., Larrosa, M., Yanez-Gascon, M. J., Fromentin, E., Flanagan, J., et al. (2013). Bioavailability of the major bioactive diterpenoids in a rosemary extract: Metabolic profile in the intestine, liver, plasma, and brain of Zucker rats. Molecular Nutrition & Food Research, 57(10), 1834–1846.
Sachdeva, A. K., & Chopra, K. (2015). Lycopene abrogates Aβ(1-42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer’s disease. Journal of Nutritional Biochemistry, 26, 736–744.
Sagy-Bross, C., Hadad, N., & Levy, R. (2013). Cytosolic phospholipase A2α upregulation mediates apoptotic neuronal death induced by aggregated amyloid-β peptide1-42. Neurochemistry International, 63, 541–550.
Samieri, C., Feart, C., Letenneur, L., Dartigues, J. F., Peres, K., Auriacombe, S., et al. (2008). Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk. American Journal of Clinical Nutrition, 88(3), 714–721.
Samieri, C., Feart, C., Proust-Lima, C., Peuchant, E., Dartigues, J. F., Amieva, H., et al. (2011). Omega-3 fatty acids and cognitive decline: Modulation by ApoEε4 allele and depression. Neurobiology of Aging, 32(2317), e2313–e2322.
Samieri, C., Maillard, P., Crivello, F., Proust-Lima, C., Peuchant, E., Helmer, C., et al. (2012). Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe. Neurology, 79(7), 642–650.
Saraiva, M., & O’Garra, A. (2010). The regulation of IL-10 production by immune cells. Nature Reviews Immunology, 10(3), 170.
Serhan, C. N. (2007). Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annual Review of Immunology, 25, 101–137.
Serhan, C. N., Arita, M., Hong, S., & Gotlinger, K. (2004). Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Lipids, 39, 1125–1132.
Soderberg, M., Edlund, C., Kristensson, K., & Dallner, G. (1991). Fatty acid composition of brain phospholipids in aging and in Alzheimer’s disease. Lipids, 26, 421–425.
Solomonov, Y., Hadad, N., & Levy, R. (2016). Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 13, 134–146.
Stoll, A. L., Severus, W. E., Freeman, M. P., Rueter, S., Zboyan, H. A., Diamond, E., et al. (1999). Omega 3 fatty acids in bipolar disorder: A preliminary double-blind, placebo-controlled trial. Archives of General Psychiatry, 56, 407–412.
Superko, H. R., Superko, S. M., Nasir, K., Agatston, A., & Garrett, B. C. (2013). Omega-3 fatty acid blood levels: Clinical significance and controversy. Circulation, 128, 2154–2161.
Surette, M. E. (2008). The science behind dietary omega-3 fatty acids. Canadian Medical Association Journal, 178, 177–180.
Szaingurten-Solodkin, I., Hadad, N., & Levy, R. (2009). Regulatory role of cytosolic phospholipase A2α in NADPH oxidase activity and in inducible nitric oxide synthase induction by aggregated Aβ1–42 in microglia. Glia, 57, 1727–1740.
Tak, P., & Firestein, G. (2001). NF-κB: A key role in inflammatory diseases. Journal of Clinical Investigation, 107, 7–11.
Tan, C., Xue, J., Lou, X., Abbas, S., Guan, Y., Feng, B., et al. (2014). Liposomes as delivery systems for carotenoids: Comparative studies of loading ability, storage stability and in vitro release. Food Function, 5, 1232–1240.
Tarahovsky, Y. S., Muzafarov, E. N., & Kim, Y. A. (2008). Rafts making and rafts braking: How plant flavonoids may control membrane heterogeneity. Molecular and Cellular Biochemistry, 314, 65–71.
Thomas, J., Thomas, C. J., Radcliffe, J., & Itsiopoulos, C. (2015). Omega-3 fatty acids in early prevention of inflammatory neurodegenerative disease: A focus on Alzheimer’s disease. BioMed Research International, 2015, 172801–172814.
Walfisch, Y., Walfisch, S., Agbaria, R., Levy, J., & Sharoni, Y. (2003). Lycopene in serum, skin and adipose tissues after tomato-oleoresin supplementation in patients undergoing haemorrhoidectomy or peri-anal fistulotomy. British Journal of Nutrition, 90, 759–766.
Wu, W., Li, Y., Wu, Y., Zhang, Y., Wang, Z., & Liu, X. (2015). Lutein suppresses inflammatory responses through Nrf2 activation and NF-κB inactivation in lipopolysaccharide-stimulated BV-2 microglia. Molecular Nutrition & Food Research, 59(9), 1663–1673.
Yanagitai, M., Itoh, S., Kitagawa, T., Takenouchi, T., Kitani, H., & Satoh, T. (2012). Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia. Biochemical and Biophysical Research Communications, 418, 22–26.