Colormapping: a non-mathematical procedure for genetic mapping
Tóm tắt
We describe a new procedure, called colormapping, a non-mathematical method for genetic mapping. Numerical scores representing the genotypes of the markers are converted to colors and these are used to display the genotypes of the markers for each individual in a segregating population. Color genotypes are arranged in a matrix where each row corresponds to a marker – ordered according to their position in the appropriate Linkage Group – and each column represents an individual in the mapping population. The picture is called colormap by which the genotypes of the chromosomal segments can be shown for each individual in the segregating population. A colormap can be used for whole genome analysis which is profitable in genetic and breeding experiments and is suitable for genetic mapping, too. The location of a new marker is found by recognizing similarities between the color pattern of the individuals for the new marker and the ordered markers in the colormap. Colormapping can also be used to find linkages which cannot be determined unambiguously by conventional mapping programs. Moreover, colormaps are extremely powerful for troubleshooting by indicating inaccurate genotypes caused by errors of different origin. Colormap(ping) is generally applicable to genetic mapping/analysis of any organisms.
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