Coexpression of SGLT1 and EGFR is associated with tumor differentiation in oral squamous cell carcinoma

Shigaku = Odontology - Tập 100 Số 2 - Trang 156-163 - 2012
Yasuko Hanabata1, Yusuke Nakajima1, Keiichi Morita1, Kou Kayamori2, Ken Omura1
1Department of Oral and Maxillofacial Surgery, Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
2Department of Oral Pathology, Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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Sheu JJ, Hung CH, Wan L, et al. Functional genomic analysis identified epidermal growth factor receptor activation as the most common genomic event in oral squamous cell carcinoma. Cancer Res. 2009;69:2568–76.

Gasco M, Crook T. The p53 network in head and neck cancer. Oral Oncol. 2003;39:222–31.

Rautava J, Lee KJ, Miettinen PJ, et al. ERBB receptor in developing, dysplastic and malignant oral epithelia. Oral Oncol. 2008;44:227–35.

Ang KK, Berkey BA, Tu X, et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res. 2002;62:7350–6.

Yarden Y, Sliwkowski MX. Untangling the ErbB signaling network. Nat Rev Mol Cell Biol. 2001;2:127–37.

Lo HW, Chieh SC, Seyed MA, et al. Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer Cell. 2005;7:575–89.

Scaltriti M, Baselga J. The epidermal growth factor receptor pathway: a model for targeted therapy. Clin Cancer Res. 2006;12:5268–72.

Wang SC, Nakajima Y, Yu YL, et al. Tyrosine phosphorylation controls PCNA function. Nat Cell Biol. 2006;8:1359–68.

Kiyota A, Shintani S, Mihara M, et al. Expression of truncated epidermal growth factor receptor in oral squamous cell carcinoma. Cancer Lett. 2000;161:9–15.

Laimer K, Spizzo G, Gastl G, et al. High EGFR expression predicts poor prognosis in patients with squamous cell carcinoma of the oral cavity and oropharynx: a TMA-based immunohistochemical analysis. Oral Oncol. 2007;43:193–8.

Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer. 2004;4:361–70.

Gupta AK, McKenna WG, Weber CN, et al. Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res. 2002;8:885–92.

Shintani S, Li C, Mihara M, et al. Gefitinib (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, mediates the inhibition of lymph node metastasis in oral cancer cells. Cancer Lett. 2003;201:149–55.

Molinari F, Martin V, Saletti P, et al. Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant. Br J Cancer. 2009;100:1087–94.

Dancey JE, Freidlin B. Targeting epidermal growth factor receptor—are we missing the mark? Lancet. 2003;362:62–4.

Tonb D, Mehta R, Wang H, et al. Short-term effect of epidermal growth factor on glucose uptake in endoscopic biopsies. Dig Dis Sci. 2003;48:1614–8.

Engelman JA, Cantley LC. A sweet new role for EGFR in cancers. Cancer Cell. 2008;13:375–6.

Weihua Z, Tsan R, Huang WC, et al. Survival of cancer cells is mediated by EGFR independent of its kinase activity. Cancer Cell. 2008;13:385–93.

Chiang WF, Liu SY, Yen CY, et al. Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas. Oral Oncol. 2008;44:270–6.

Molinolo AA, Amornphimoltham P, Squarize CH, et al. Dysregulated molecular networks in head and neck carcinogenesis. Oral Oncol. 2008;45:324–34.

Sobin LH, Wittekind C. International Union Against Cancer: TNM classification of malignant tumors. 6th ed. Berlin: Springer; 1987.

WHO International Histological Classification of Tumors. Histological typing of cancer and precancer of the oral mucosa, 2nd edn. 1997.

Yamamoto E, Kohama G, Sunakawa H, et al. Mode of invasion, bleomycin sensitivity, and clinical course in squamous cell carcinoma of the oral cavity. Cancer. 1983;51:2175–80.

Chanwit P, Morita K, Kuribayashi Y, et al. DNA amplification and expression of FADD in oral squamous cell carcinoma. J Oral Pathol Med. 2010;39:525–32.

Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Cancer. 2004;4:891–9.

Helmke BM, Reisser C, Idzkoe M, et al. Expression of SGLT-1 in preneoplastic and neoplastic lesions of head and neck. Oral Oncol. 2004;40:28–35.

Ganapathy V, Thangaraju M, Prasad PD, et al. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol Ther. 2009;121:29–40.

Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell. 1993;73:713–24.

Yamamoto E, Miyakawa A, Kohama G. Mode of invasion and lymph node metastasis in squamous cell carcinoma of the oral cavity. Head Neck Surg. 1984;6:938–47.