Coenzyme Q10 in plasma and erythrocytes: comparison of antioxidant levels in healthy probands after oral supplementation and in patients suffering from sickle cell anemia

Clinica Chimica Acta - Tập 326 - Trang 155-161 - 2002
Petra Niklowitz1, Thomas Menke1, Thomas Wiesel1, Ertan Mayatepek2, Johannes Zschocke2, Jürgen G Okun2, Werner Andler1
1Vestische Kinderklinik Datteln, University Witten-Herdecke, Dr.-Friedrich-Steiner-Str. 5, D-45711 Datteln, Germany
2Division of Metabolic and Endocrine Diseases, University Children's Hospital Heidelberg, Im Neuenheimer Feld 150, 69120 Heidelberg, Germany

Tài liệu tham khảo

Brandt, 1997, Role of deprotonation events in ubihydroquinone: cytochrome c oxidoreductase from bovine heart and yeast mitochondria, Biochemistry, 36, 11234, 10.1021/bi970968g Okun, 1999, Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH: ubiquinone oxidoreductase), J. Biol. Chem., 274, 2625, 10.1074/jbc.274.5.2625 Stocker, 1991, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does α-tocopherol, Proc. Natl. Acad. Sci. U. S. A., 88, 1646, 10.1073/pnas.88.5.1646 Lenaz, 1998, Oxidative stress, antioxidant defences and aging, BioFactors, 8, 195, 10.1002/biof.5520080305 Lücker, 1984, Pharmacokinetics of coenzyme ubidecarenone in healthy volunteers, 143 Tomono, 1986, Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man, Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 536 Bogentoft, 1991, Biopharmaceutical aspects of intravenous and oral administration of coenzyme Q10, 215 Yuzuriha, 1983, Transport of [14C]Coenzyme Q10 from the liver to other tissues after intravenous administration to guinea pigs, Biochim. Biophys. Acta, 759, 286, 10.1016/0304-4165(83)90325-2 Chan, 1999, Interaction of antioxidants and their implication in genetic anemia, Exp. Biol. Med., 222, 274, 10.1046/j.1525-1373.1999.d01-144.x Menke, 2000, Simultaneous detection of ubiquinol-10, ubiquinone-10, and tocopherols in human plasma microsamples and macrosamples as a marker of oxidative damage in neonates and infants, Anal. Biochem., 282, 209, 10.1006/abio.2000.4579 Sierra, 1992, Liquid chromatography determination of α-tocopherol in erythrocytes, Clin. Chim. Acta, 208, 119, 10.1016/0009-8981(92)90029-P Kröger, 1966, On the role of ubiquinone in mitochondria: II. Redox reactions of ubiquinone under the control of oxidative phosphorylation, Biochem. Z., 344, 317 Weber, 1994, Effect of dietary coenzyme Q10 as an antioxidant in human plasma, Mol. Aspects Med., 15, 97, 10.1016/0098-2997(94)90018-3 Littarru, 1991, Metabolic and diagnostic implications of human blood CoQ10 levels, 167 Ernster, 1995, Biochemical, physiological and medical aspects of ubiquinone function, Biochim. Biophys. Acta, 1271, 195, 10.1016/0925-4439(95)00028-3 Lonnrot, 1998, The effects of lifelong ubiquinone Q10 supplementation on the Q9 and Q10 tissue concentrations and life span of male rats and mice, Biochem. Mol. Biol. Int., 44, 727 Moyano, 1997, Tocopherol in inborn errors of intermediary metabolism, Clin. Chim. Acta, 263, 147, 10.1016/S0009-8981(97)00061-2 Hebbel, 1988, Accelerated autooxidation and heme loss due to instability of sickle hemoglobin, Proc. Natl. Acad. Sci. U. S. A., 85, 237, 10.1073/pnas.85.1.237