Clues Provided by Animal Models of Arthritis

Bartholomew, 1979, Antigenic bacterial polysaccharide in rheumatoid synovial effusions, Arthritis Rheum, 22, 969, 10.1002/art.1780220904 Beaman, 1984, Messenger RNA for an antigen-specific binding molecule from an antigen-specific T cell hybrid, Proc Natl Acad Sci USA, 81, 1524, 10.1073/pnas.81.5.1524 Blake, 1984, The effect of synovial iron on the progression of rheumatoid disease: A histologic assessment of patients with early rheumatoid synovitis, Arthritis Rheum, 27, 495, 10.1002/art.1780270503 Blake, 1981, The importance of iron in rheumatoid disease, Lancet, 2, 1142, 10.1016/S0140-6736(81)90590-0 Brahn, 1985, Abrogation of collagen arthritis and modulation of delayed-type hypersensitivity (DTH) by a type II collagen reactive T cell line (Abstract), Arthritis Rheum, 28, S26 Brahn, 1984, Antigen-specific suppression of collagen arthritis by adoptive transfer of spleen cells, Clin Immunol Immunopath, 31, 124, 10.1016/0090-1229(84)90197-1 Breedveld FC, Dynesius-Trentham R, de Sousa M, et al: Immunomodulation of collagen arthritis by iron. (Submitted for publication) Bromley, 1984, Mast cells at sites of cartilage erosion in the rheumatoid joint, Ann Rheum Dis, 43, 76, 10.1136/ard.43.1.76 Burgos-Vargas, 1986, Antibodies to peptidoglycan in juvenile onset ankylosing spondylitis and pauciarticular onset juvenile arthritis associated with chronic iridocyclitis, J Rheumatol, 13, 760 Castor, 1960, The microscopic structure of normal human synovial tissue, Arthritis Rheum, 3, 140, 10.1002/art.1780030205 Cathcart, 1986, Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen, Lab Invest, 54, 26 Caulfield, 1982, Morphologic demonstration of two stages in the development of type II collagen-induced arthritis, Lab Invest, 46, 321 Caulfield, 1987, Arthritogenic factor (AF) stimulates mast cell degranulation and sequential migration of neutrophils and monocytes into the knees of rats (Abstract), Fed Proc, 46, 731 Combe, 1985, Interleukin 2 in rheumatoid arthritis: Production of and response to interleukin in rheumatoid synovial fluid, synovial tissue and peripheral blood, Clin Exp Immunol, 59, 520 Courtenay, 1980, Immunisation against heterologous type II collagen induces arthritis in mice, Nature, 283, 666, 10.1038/283666a0 Cromartie, 1977, Arthritis in rats after systemic injection of streptococcal cells or cell walls, J Exp Med, 146, 1585, 10.1084/jem.146.6.1585 de Sousa, 1986, Potential of indium-111 to measure inflammatory arthritis, J Rheumatol, 13, 1108 de Sousa, 1987, Activation of the synovium by iron in rats, Arthritis Rheum (Abstract), 30, 510 Englert, 1985, Pretreatment of rats with anticollagen IgG renders them resistant to active type II collagen arthritis, Cell Immunol, 90, 258, 10.1016/0008-8749(85)90188-1 Golub, 1983, Minocycline reduces gingival collagenolytic activity during diabetes: Preliminary observations and a proposed new mechanism of action, J Periodontal Res, 18, 516, 10.1111/j.1600-0765.1983.tb00388.x Greenwald, 1986, Minocycline (Min) inhibits rheumatoid synovial collagenase (C Gase) in vivo and in vitro, Arthritis Rheum, 29, S7 Helfgott, 1986, Presence of a type II collagen binding arthritogenic lymphokine in adjuvant arthritis (Abstract), Arthritis Rheum, 29, S39 Helfgott, 1985, An arthritogenic lymphokine in the rat, J Exp Med, 162, 1531, 10.1084/jem.162.5.1531 Holmdahl, 1986, Collagen II immunity and rheumatoid factors (Abstract), Scand J Immunol, 24, 473 Holoshitz, 1986, T lymphocytes of rheumatoid arthritis patients show augmented reactivity to a fraction of mycobacteria cross-reactive with cartilage, Lancet, 2, 305, 10.1016/S0140-6736(86)90003-6 Holoshitz, 1984, Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II, J Clin Invest, 73, 211, 10.1172/JCI111193 Holoshitz, 1983, Lines of T lymphocytes induce or vaccinate against autoimmune arthritis, Science, 219, 56, 10.1126/science.6336851 Johnson, 1984, Antibody to streptococcal cell wall peptidoglycan-polysaccharide polymers in seropositive and seronegative rheumatic disease, Clin Exp Immunol, 55, 115 Kaibara, 1983, Paradoxical effects of cyclosporin A on collagen arthritis in rats, J Exp Med, 158, 2007, 10.1084/jem.158.6.2007 Kieval RI, Young CT, Prohazka D, et al: Suppression of experimental synovitis by amiprilose hydrochloride (Therafectin): A potential novel mechanism of action. (Submitted for publication) Klareskog, 1982, Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis, Proc Natl Acad Sci USA, 79, 3632, 10.1073/pnas.79.11.3632 Kourounakis, 1976, Restoration of diminished T cell function in adjuvant induced disease by methotrexate, J Rheumatol, 3, 346 Kremer, 1985, Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis, Lancet, 1, 184, 10.1016/S0140-6736(85)92024-0 Lehman, 1984, Lactobacillus casei cell wall induced arthritis in rats: Cell wall fragment distribution and persistence in chronic arthritis susceptible Lew/N and resistant F334/N rats, Arthritis Rheum, 27, 939, 10.1002/art.1780270815 McCune, 1982, Immunosuppression by fractionated total lymphoid irradiation in collagen arthritis, Arthritis Rheum, 25, 532, 10.1002/art.1780250507 McCune, 1984, Connective tissue disease can develop in rats either spontaneously or after total lymphoid irradiation, J Rheumatol, 11, 410 Miyasaka, 1984, Interleukin 2 deficiencies in rheumatoid arthritis and systemic lupus erythematosus, Clin Immunol Immunopath, 31, 109, 10.1016/0090-1229(84)90195-8 Muirden, 1970, The anaemia of rheumatoid arthritis: The significance of iron deposits in the synovial membrane, Aust Ann Med, 2, 94 Nagao, 1980, Muramyl dipeptide-induced adjuvant arthritis, Infect Immun, 28, 624, 10.1128/iai.28.2.624-626.1980 Pardo, 1984, Analysis of in vitro polyclonal B cell differentiation responses to bacterial peptidoglycan and pokeweed mitogen in rheumatoid arthritis, Clin Exp Immunol, 56, 253 Pearson, 1961, Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant: V. Changes affecting the skin and mucous membranes: Comparison of the experimental process with human disease, J Exp Med, 113, 485, 10.1084/jem.113.3.485 Pincus, 1987 Prickett, 1984, Dietary fish oil augments the induction of arthritis in rats immunized with type II collagen, J Immunol, 132, 725, 10.4049/jimmunol.132.2.725 Ridge SC, Rath N, Calivan J, et al: Studies on the effect of D-penicillamine, gold thioglucose and methotrexate on streptococcal cell wall arthritis. J Rheumatol (In press) Rogers, 1983, Exacerbation of collagen arthritis by noise stress, J Rheumatol, 10, 651 Rogers, 1980, Effect of psychological stress on the induction of arthritis in rats, Arthritis Rheum, 23, 1337, 10.1002/art.1780231202 Schoen, 1982, Antigen-specific suppression of type II collagen-induced arthritis by collagen-coupled spleen cells, J Immunol, 128, 717, 10.4049/jimmunol.128.2.717 Skinner, 1971, Tetracycline in the treatment of rheumatoid arthritis: A double blind controlled study, Arthritis Rheum, 14, 727, 10.1002/art.1780140607 Strober, 1985, Efficacy of total lymphoid irradiation in intractable rheumatoid arthritis: A double-blind, randomized trial, Ann Intern Med, 102, 441, 10.7326/0003-4819-102-4-441 Suarez CR, Pickett WC, Bell DH, et al: Effect of low dose methotrexate on neutrophil chemotaxis induced by leukotriene B4 and complement C5a. J Rheumatol (In press) Sutherland, 1981, Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin, Proc Natl Acad Sci USA, 78, 4515, 10.1073/pnas.78.7.4515 Thompson, 1984, A controlled two-centre trial of parenteral methotrexate therapy for refractory rheumatoid arthritis, J Rheumatol, 11, 760 Trentham, 1982, Collagen arthritis as a relevant model for rheumatoid arthritis: Evidence pro and con, Arthritis Rheum, 25, 911, 10.1002/art.1780250801 Trentham DE, Belli JA, Bloomer WD, et al: 2,000 centigray total lymphoid irradiation for refractory rheumatoid arthritis. Arthritis Rheum (In press) Trentham, 1982, Augmentation of collagen arthritis by synthetic analogues of retinoic acid, J Immunol, 129, 2668 Trentham, 1983, Attenuation of an adjuvant arthritis by type II collagen, J Immunol, 130, 2689, 10.4049/jimmunol.130.6.2689 Trentham, 1978, Cellular sensitivity to collagen in rheumatoid arthritis, N Engl J Med, 299, 327, 10.1056/NEJM197808172990703 Trentham, 1977, Autoimmunity to type II collagen: An experimental model of arthritis, J Exp Med, 146, 857, 10.1084/jem.146.3.857 Utsinger, 1980, Bypass disease: A bacterial antigen-antibody systemic immune complex disease, Arthritis Rheum, 23, 758 Van Eden, 1985, Arthritis induced by a T lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans, Proc Natl Acad Sci USA, 82, 5117, 10.1073/pnas.82.15.5117 Wasserman, 1986, Immunoglobulin E-mast cell mediator system, 448 Weinblatt, 1985, Efficacy of low-dose methotrexate in rheumatoid arthritis, N Engl J Med, 312, 818, 10.1056/NEJM198503283121303 Weinblatt, 1987, Cyclosporin A treatment of refractory rheumatoid arthritis, Arthritis Rheum, 30, 11, 10.1002/art.1780300102 Weinblatt ME, Coblyn JS, Holdsworth DE, et al: Long-term prospective trial of low dose methotrexate in rheumatoid arthritis. (Submitted for publication) Weinblatt ME, Fraser PA, Anderson RJ, et al: Diminution of the T8-subset by amiprilose hydrochloride in rheumatoid arthritis. J Rheumatol (In press) Welles, 1985, Studies on the effect of low dose methotrexate on rat adjuvant arthritis, J Rheumatol, 12, 904 Williams, 1985, Comparison of low-dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis: A controlled clinical trial, Arthritis Rheum, 28, 721, 10.1002/art.1780280702 Wooley, 1983, Genetic control of type II collagen-induced arthritis in mice: Factors influencing disease susceptibility and evidence for multiple MHC-associated gene control, Transplant Proc, 15, 180 Wynne-Roberts, 1978, Light- and electron-microscopic findings of juvenile rheumatoid arthritis synovium: Comparison with normal juvenile synovium, Semin Arthritis Rheum, 7, 287, 10.1016/0049-0172(78)90027-6 Zurier, 1982, Prostaglandins, immune responses and murine lupus, Arthritis Rheum, 25, 804, 10.1002/art.1780250718