Clinical trials report

American Academy of Pediatrics, Subcommittee on Management of Acute Otitis Media: Diagnosis and management of acute otitis media. Pediatrics 2004, 113:1451–1465. Little P, Gould C, Williamson I, et al.: Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media. BMJ 2001, 322:336–342. Marchetti F, Ronfani L, Nibali SC, et al.: Delayed prescription may reduce the use of antibiotics for acute otitis media: a prospective observational study in primary care. Arch Pediatr Adolesc Med 2005, 159:679–684. Siegel RM, Kiely M, Bien JP, et al.: Treatment of otitis media with observation and a safety-net antibiotic prescription. Pediatrics 2003, 112:527–531. Finkelstein JA, Stille CJ, Rifas-Shiman SL, Goldmann D: Watchful waiting for acute otitis media: are parents and physicians ready? Pediatrics 2005, 115:1466–1473. Le Saux N, Gaboury I, Baird M, et al.: A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age. CMAJ 2005, 172:335–341. Bertin L, Pons G, d’Athis P, et al.: A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children. Fundam Clin Pharmacol 1996, 10:387–392. Hoberman A, Paradise JL, Reynolds EA, Urkin J: Efficacy of Auralgan for treating ear pain in children with acute otitis media. Arch Pediatr Adolesc Med 1997, 151:675–678.