Clinical photoacoustic imaging platforms

Bell AG. The photophone. J Franklin Inst. 1880;110:237–48.

Valluru KS, Wilson KE, Willmann JK. Photoacoustic Imaging in oncology: translational preclinical and early clinical experience. Radiology. 2016;280:332–49.

Upputuri PK, Pramanik M. Recent advances toward preclinical and clinical translation of photoacoustic tomography: a review. J Biomed Opt. 2017;22:041006–041006.

Valluru KS, Willmann JK. Clinical photoacoustic imaging of cancer. Ultrasonography. 2016;35:267–80.

Cai X, Kim C, Pramanik M, Wang LV. Photoacoustic tomography of foreign bodies in soft biological tissue. J Biomed Opt. 2011;16:046017.

Zhang Y, Jeon M, Rich LJ, Hong H, Geng J, Zhang Y, Shi S, Barnhart TE, Alexandridis P, Huizinga JD. Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines. Nat Nanotechnol. 2014;9:631–8.

Jeon M, Kim C. Multimodal photoacoustic tomography. IEEE Trans Multimedia. 2013;15:975–82.

Lee C, Han S, Kim S, Jeon M, Jeon MY, Kim C, Kim J. Combined photoacoustic and optical coherence tomography using a single near-infrared supercontinuum laser source. Appl Opt. 2013;52:1824–8.

Kim JY, Lee C, Park K, Han S, Kim C. High-speed and high-SNR photoacoustic microscopy based on a galvanometer mirror in non-conducting liquid. Sci Rep. 2016;6:34803.

Park K, Kim JY, Lee C, Jeon S, Lim G, Kim C. Handheld photoacoustic microscopy probe. Sci Rep. 2017;7:13359.

Kim C, Favazza C, Wang LV. In vivo photoacoustic tomography of chemicals: high-resolution functional and molecular optical imaging at new depths. Chem Rev. 2010;110:2756–82.

Yapici MK, Kim C, Chang C-C, Jeon M, Guo Z, Cai X, Zou J, Wang LV. Parallel acoustic delay lines for photoacoustic tomography. J Biomed Opt. 2012;17:116019–116019.

Park J, Jeon S, Meng J, Song L, Lee JS, Kim C. Delay-multiply-and-sum-based synthetic aperture focusing in photoacoustic microscopy. J Biomed Opt. 2016;21:036010–036010.

Laskey W, Aspelin P, Davidson C, Rudnick M, Aubry P, Kumar S, Gietzen F, Wiemer M, D. S. Group. Nephrotoxicity of iodixanol versus iopamidol in patients with chronic kidney disease and diabetes mellitus undergoing coronary angiographic procedures. Am Heart J. 2009;158:822–8.

Mailloux LU, Napolitano B, Bellucci AG, Vernace M, Wilkes BM, Mossey RT. Renal vascular disease causing end-stage renal disease, incidence, clinical correlates, and outcomes: a 20-year clinical experience. Am J Kidney Dis. 1994;24:622–9.

Abuelo GJ. Diagnosing vascular causes of renal failure. Ann Intern Med. 1995;123:601–14.

Greenland P, Alpert JS, Beller GA, Benjamin EJ, Budoff MJ, Fayad ZA, Foster E, Hlatky MA, Hodgson JM, Kushner FG. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. J Am Coll Cardiol. 2010;56:e50–103.

Maslov K, Zhang HF, Wang LV. Effects of wavelength-dependent fluence attenuation on the noninvasive photoacoustic imaging of hemoglobin oxygen saturation in subcutaneous vasculature in vivo. Inverse Prob. 2007;23:S113.

Zhang HF, Maslov K, Sivaramakrishnan M, Stoica G, Wang LV. Imaging of hemoglobin oxygen saturation variations in single vessels in vivo using photoacoustic microscopy. Appl Phys Lett. 2007;90:053901.

Jeon M, Kim J, Kim C. Multiplane spectroscopic whole-body photoacoustic imaging of small animals in vivo. Med Biol Eng Comput. 2016;54:283–94.

Park S, Lee C, Kim J, Kim C. Acoustic resolution photoacoustic microscopy. Biomed Eng Lett. 2014;4:213–22.

Lee C, Jeon M, Jeon MY, Kim J, Kim C. In vitro photoacoustic measurement of hemoglobin oxygen saturation using a single pulsed broadband supercontinuum laser source. Appl Opt. 2014;53:3884–9.

Ku G, Wang X, Xie X, Stoica G, Wang LV. Imaging of tumor angiogenesis in rat brains in vivo by photoacoustic tomography. Appl Opt. 2005;44:770–5.

Lao Y, Xing D, Yang S, Xiang L. Noninvasive photoacoustic imaging of the developing vasculature during early tumor growth. Phys Med Biol. 2008;53:4203.

Mehrmohammadi M, Yoon SJ, Yeager D, Emelianov SY. Photoacoustic imaging for cancer detection and staging. Curr Mol Imaging. 2013;2:89–105.

Lakshman M, Needles A. Screening and quantification of the tumor microenvironment with micro-ultrasound and photoacoustic imaging. Nat Methods. 2015;12.

Erpelding TN, Kim C, Pramanik M, Jankovic L, Maslov K, Guo Z, Margenthaler JA, Pashley MD, Wang LV. Sentinel lymph nodes in the rat: noninvasive photoacoustic and US imaging with a clinical US system. Radiology. 2010;256:102–10.

Akers WJ, Edwards WB, Kim C, Xu B, Erpelding TN, Wang LV, Achilefu S. Multimodal sentinel lymph node mapping with single-photon emission computed tomography (SPECT)/computed tomography (CT) and photoacoustic tomography. Transl Res. 2012;159:175–81.

Taruttis A, Timmermans AC, Wouters PC, Kacprowicz M, van Dam GM, Ntziachristos V. Optoacoustic imaging of human vasculature: feasibility by using a handheld probe. Radiology. 2016;281:256–63.

Irisawa K, Hirota K, Hashimoto A, Murakoshi D, Ishii H, Tada T, Wada T, Hayakawa T, Azuma R, Otani N, Itoh K, Ishihara M. Photoacoustic imaging system for peripheral small-vessel imaging based on clinical ultrasound technology. Proc SPIE. 2016;9708:970807.

van den Berg PJ, Daoudi K, Bernelot Moens HJ, Steenbergen W. Feasibility of photoacoustic/ultrasound imaging of synovitis in finger joints using a point-of-care system. Photoacoustics. 2017;8:8–14.

Jo J, Xu G, Marquardt A, Girish G, Wang X. Photoacoustic evaluation of human inflammatory arthritis in human joints. Proc. SPIE. 2017;10064:1006409.

Weidner N. Tumor angiogenesis: review of current applications in tumor prognostication. In: Seminars in diagnostic pathology; 1993. p. 302–13.

Brenchley P. Antagonising angiogenesis in rheumatoid arthritis. Ann Rheum Dis. 2001;60:71–4.

Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst. 2001;93:266–76.

Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Guyton RA, Hochman JS, Kovacs RJ. Management of patients with peripheral artery disease (compilation of 2005 and 2011 ACCF/AHA guideline recommendations). Circulation. 2013;127:1425–43.

Park S, Jang J, Kim J, Kim YS, Kim C. Real-time triple-modal photoacoustic, ultrasound, and magnetic resonance fusion imaging of humans. IEEE Trans Med Imaging. 2017;36:1912–21.

Ishihara M, Horiguchi A, Shinmoto H, Tsuda H, Irisawa K, Wada T, Asano T. Comparison of transrectal photoacoustic, Doppler, and magnetic resonance imaging for prostate cancer detection. Proc SPIE. 2016;9708:970852.

Guo Z, Li L, Wang LV. On the speckle-free nature of photoacoustic tomography. Med Phys. 2009;36:4084–8.

Jacques SL. Optical properties of biological tissues: a review. Phys Med Biol. 2013;58:R37.

Kim C, Erpelding TN, Jankovic L, Pashley MD, Wang LV. Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system. Biomed Opt Exp. 2010;1:278–84.

Kang J, Zhang HK, Rahmim A, Wong DF, Kang JU, Boctor EM. Toward high-speed transcranial photoacoustic imaging using compact near-infrared pulsed LED illumination system. In: Photons plus ultrasound: imaging and sensing; 2017. p. 100643B.

Deán-Ben XL, Razansky D. On the link between the speckle free nature of optoacoustics and visibility of structures in limited-view tomography. Photoacoustics. 2016;4:133–40.

Deán-Ben XL, Razansky D. Functional optoacoustic human angiography with handheld video rate three dimensional scanner. Photoacoustics. 2013;1:68–73.

Kim J, Park S, Jung Y, Chang S, Park J, Zhang Y, Lovell JF, Kim C. Programmable real-time clinical photoacoustic and ultrasound imaging system. Sci Rep. 2016;6:35137.

Yang M, Zhao L, He X, Su N, Zhao C, Tang H, Hong T, Li W, Yang F, Lin L. Photoacoustic/ultrasound dual imaging of human thyroid cancers: an initial clinical study. Biomed Opt Exp. 2017;8:3449–57.

Dima A, Ntziachristos V. Non-invasive carotid imaging using optoacoustic tomography. Opt Exp. 2012;20:25044–57.

Diot G, Metz S, Noske A, Liapis E, Schroeder B, Ovsepian SV, Meier R, Rummeny E, Ntziachristos V. Multispectral optoacoustic tomography (MSOT) of human breast cancer. Clin Cancer Res. 2017;23:6912–22.

Oeri M, Bost W, Sénégond N, Tretbar S, Fournelle M. Hybrid photoacoustic/ultrasound tomograph for real-time finger imaging. Ultrasound Med Biol. 2017;43:2200–12.

Ermilov S, Su R, Zamora M, Hernandez T, Nadvoretsky V, Oraevsky A. Optoacoustic angiography of peripheral vasculature. In: Proceedings of SPIE; 2012. p. 82230D.

Toi M, Asao Y, Matsumoto Y, Sekiguchi H, Yoshikawa A, Takada M, Kataoka M, Endo T, Kawaguchi-Sakita N, Kawashima M, Fakhrejahani E, Kanao S, Yamaga I, Nakayama Y, Tokiwa M, Torii M, Yagi T, Sakurai T, Togashi K, Shiina T. Visualization of tumor-related blood vessels in human breast by photoacoustic imaging system with a hemispherical detector array. Sci Rep. 2017;7:41970.

Szabo TL, Lewin PA. Ultrasound transducer selection in clinical imaging practice. J Ultrasound Med. 2013;32:573–82.

Garcia-Uribe A, Erpelding TN, Krumholz A, Ke H, Maslov K, Appleton C, Margenthaler JA, Wang LV. Dual-modality photoacoustic and ultrasound imaging system for noninvasive sentinel lymph node detection in patients with breast cancer. Sci Rep. 2015;5:15748.

Neuschler EI, Butler R, Young CA, Barke LD, Bertrand ML, Böhm-Vélez M, Destounis S, Donlan P, Grobmyer SR, Katzen J. A pivotal study of optoacoustic imaging to diagnose benign and malignant breast masses: a new evaluation tool for radiologists. Radiology. 2017; 172228.

Kim J, Kim M-H, Jo K, Ha J, Kim Y, Lim D-J, Kim C. Photoacoustic analysis of thyroid cancer in vivo: a pilot study. In: Proceedings of SPIE; 2017. p. 1006408-1.

Hai P, Zhou Y, Liang J, Li C, Wang LV. Photoacoustic tomography of vascular compliance in humans. J Biomed Opt. 2015;20:126008.

Butler R, Stavros A, Lavin P, Ulissey M, Tucker F. Opto-acoustic breast imaging: imaging-pathology correlation of opto-acoustic features respecting malignancy; 2015.

Ermilov SA, Fronheiser MP, Brecht H-P, Su R, Conjusteau A, Mehta K, Otto P, Oraevsky AA. Development of laser optoacoustic and ultrasonic imaging system for breast cancer utilizing handheld array probes. In: SPIE BiOS; 2009. p. 10.

Ishihara M, Tsujita K, Horiguchi K, Irisawa K, Komatsu T, Ayaori M, Hirasawa T, Kasamatsu T, Hirota K, Tsuda H. Development of photoacoustic imaging technology overlaid on ultrasound imaging and its clinical application. In: SPIE BiOS; 2015. p. 93232K–93232K-7.

Hai P, Zhou Y, Gong L, Wang LV. Quantitative photoacoustic elastography in humans. J Biomed Opt. 2016;21:5.

Daoudi K, van den Berg PJ, Rabot O, Kohl A, Tisserand S, Brands P, Steenbergen W. Handheld probe integrating laser diode and ultrasound transducer array for ultrasound/photoacoustic dual modality imaging. Opt Exp. 2014;22:26365–74.

Xu G, Rajian JR, Girish G, Kaplan MJ, Fowlkes JB, Carson PL, Wang X. Photoacoustic and ultrasound dual-modality imaging of human peripheral joints. J Biomed Opt. 2013;18:010502.

Yuan J, Xu G, Yu Y, Zhou Y, Carson PL, Wang X, Liu X. Real-time photoacoustic and ultrasound dual-modality imaging system facilitated with graphics processing unit and code parallel optimization. J Biomed Opt. 2013;18:086001.

Dima A, Ntziachristos V. In-vivo handheld optoacoustic tomography of the human thyroid. Photoacoustics. 2016;4:65–9.

Okawa S, Sei K, Hirasawa T, Irisawa K, Hirota K, Wada T, Kushibiki T, Furuya K, Ishihara M. In vivo photoacoustic imaging of uterine cervical lesion and its image processing based on light propagation in biological medium. Proc SPIE. 2017;10064:100642S.

Buehler A, Kacprowicz M, Taruttis A, Ntziachristos V. Real-time handheld multispectral optoacoustic imaging. Opt Lett. 2013;38:1404–6.

Rosenthal A, Razansky D, Ntziachristos V. Fast semi-analytical model-based acoustic inversion for quantitative optoacoustic tomography. IEEE Trans Med Imaging. 2010;29:1275–85.

Glatz J, Deliolanis NC, Buehler A, Razansky D, Ntziachristos V. Blind source unmixing in multi-spectral optoacoustic tomography. Opt Express. 2011;19:3175–84.

Taruttis A, Rosenthal A, Kacprowicz M, Burton NC, Ntziachristos V. Multiscale multispectral optoacoustic tomography by a stationary wavelet transform prior to unmixing. IEEE Trans Med Imaging. 2014;33:1194–202.

Brecht H-P, Su R, Fronheiser M, Ermilov SA, Conjusteau A, Oraevsky AA. Whole-body three-dimensional optoacoustic tomography system for small animals. J Biomed Opt. 2009;14:064007.

Heijblom M, Steenbergen W, Manohar S. Clinical photoacoustic breast imaging: the Twente experience. IEEE Pulse. 2015;6:42–6.

Manohar S, Kharine A, van Hespen JC, Steenbergen W, van Leeuwen TG. The twente photoacoustic mammoscope: system overview and performance. Phys Med Biol. 2005;50:2543.

Heijblom M, Piras D, Brinkhuis M, van Hespen JCG, van den Engh FM, van der Schaaf M, Klaase JM, van Leeuwen TG, Steenbergen W, Manohar S. Photoacoustic image patterns of breast carcinoma and comparisons with Magnetic resonance Imaging and vascular stained histopathology. Sci Rep. 2015;5:11778.

Kruger RA, Kuzmiak CM, Lam RB, Reinecke DR, Del Rio SP, Steed D. Dedicated 3D photoacoustic breast imaging. Med Phys. 2013;40:113301.

Chuah S, Attia A, Long V, Ho C, Malempati P, Fu C, Ford S, Lee J, Tan W, Razansky D. Structural and functional 3D mapping of skin tumours with non-invasive multispectral optoacoustic tomography. Skin Res Technol. 2017;23:221–6.

Deán-Ben X, Merčep E, Razansky D. Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues. Appl Phys Lett. 2017;110:203703.

Gateau J, Gesnik M, Chassot J-M, Bossy E. Single-side access, isotropic resolution, and multispectral three-dimensional photoacoustic imaging with rotate-translate scanning of ultrasonic detector array. J Biomed Opt. 2015;20:056004-1.

Schwarz M, Buehler A, Ntziachristos V. Isotropic high resolution optoacoustic imaging with linear detector arrays in bi-directional scanning. J Biophotonics. 2015;8:60–70.

Wang Y, Wang D, Zhang Y, Geng J, Lovell JF, Xia J. Slit-enabled linear-array photoacoustic tomography with near isotropic spatial resolution in three dimensions. Opt Lett. 2016;41:127–30.

Wang Y, Wang D, Hubbell R, Xia J. Second generation slit-based photoacoustic tomography system for vascular imaging in human. J Biophotonics. 2017;10:799–804.

Plumb AA, Huynh NT, Guggenheim J, Zhang E, Beard P. Rapid volumetric photoacoustic tomographic imaging with a Fabry-Perot ultrasound sensor depicts peripheral arteries and microvascular vasomotor responses to thermal stimuli. Eur Radiol 2017; 1–9.

Vallet M, Varray F, Kalkhoran MA, Vray D, Boutet J. Enhancement of photoacoustic imaging quality by using CMUT technology: experimental study. In: 2014 IEEE International ultrasonics symposium (IUS); 2014. p. 1296–99.

Ansari R, Zhang E, Desjardins AE, Beard PC. All-optical endoscopic probe for high resolution 3D photoacoustic tomography. Proc SPIE. 2017;10064:100641W.

Huynh N, Ogunlade O, Zhang E, Cox B, Beard P. Photoacoustic imaging using an 8-beam Fabry-Perot scanner. Proc. SPIE. 2016;9708:97082L.

Huynh N, Lucka F, Zhang E, Betcke M, Arridge S, Beard P, Cox B. Sub-sampled Fabry-Perot photoacoustic scanner for fast 3D imaging. Proc SPIE. 2017;10064:100641Y.

Vallet M, Varray F, Boutet J, Dinten J-M, Caliano G, Savoia AS, Vray D. Quantitative comparison of PZT and CMUT probes for photoacoustic imaging: experimental validation. Photoacoustics. 2017;8:48–58.

Warshavski O, Meynier C, Sénégond N, Chatain P, Rebling J, Razansky D, Felix N, Nguyen-Dinh A. Experimental evaluation of cMUT and PZT transducers in receive only mode for photoacoustic imaging. In: Proceedings of SPIE; 2016. p. 970830.