Clinical manifestations and basic mechanisms of myocardial ischemia/reperfusion injury

Tzu Chi Medical Journal - Tập 30 Số 4 - Trang 209 - 2018
Chiu-Fen Yang1
1Dr. Chiu-Fen Yang, Department of Cardiology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 707, Section 3, Chung-Yang Road, Hualien, Taiwan. E-mail: [email protected]

Tóm tắt

Từ khóa


Tài liệu tham khảo

Pfeffer, 1995, Annu Rev Med, Left ventricular remodeling after acute myocardial infarction, 455

Takii, 2010, Circ J, Trends in acute myocardial infarction incidence and mortality over 30 years in Japan: Report from the MIYAGI-AMI registry study, 93

Yellon, 2007, N Engl J Med, Myocardial reperfusion injury, 1121

Jennings, 1960, Arch Pathol, Myocardial necrosis induced by temporary occlusion of a coronary artery in the dog, 68

Bolli, 1999, Physiol Rev, Molecular and cellular mechanisms of myocardial stunning, 609

Bolli, 1992, Circulation, Myocardial 'stunning' in man, 1671

Bolli, 1990, Circulation, Mechanism of myocardial “stunning”, 723

Kim, 2001, Circ Res, A novel mechanism for myocardial stunning involving impaired Ca(2+) handling, 831

Cheirif, 1995, Am J Card Imaging, Diagnosis of myocardial stunning: A new use for myocardial contrast and dobutamine echocardiography, 261

AlJaroudi WA, Hage FG. Myocardial stunning by gated SPECT: An old tool reinvented in a stunning turn. J Nucl Cardiol 2017. doi: 10.1007/s12350-017-1127-1. [Epub ahead of print].

Ito, 2006, Nat Clin Pract Cardiovasc Med, No-reflow phenomenon and prognosis in patients with acute myocardial infarction, 499

Ramjane, 2008, Exp Clin Cardiol, The diagnosis and treatment of the no-reflow phenomenon in patients with myocardial infarction undergoing percutaneous coronary intervention, 121

Abbo, 1995, Am J Cardiol, Features and outcome of no-reflow after percutaneous coronary intervention, 778

Resnic, 2003, Am Heart J, No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention, 42

Iwakura, 2003, J Am Coll Cardiol, Association between hyperglycemia and the no-reflow phenomenon in patients with acute myocardial infarction, 1

Reffelmann, 2006, Basic Res Cardiol, The no-reflow phenomenon: A basic mechanism of myocardial ischemia and reperfusion, 359

Wit, 2001, Circ Res, Reperfusion arrhythmias and sudden cardiac death: A century of progress toward an understanding of the mechanisms, 741

Tatli, 2013, ScientificWorldJournal, Arrhythmias following revascularization procedures in the course of acute myocardial infarction: Are they indicators of reperfusion or ongoing ischemia?, 160380

Gorenek, 2015, EuroIntervention, Cardiac arrhythmias in acute coronary syndromes: Position paper from the joint EHRA, ACCA, and EAPCI task force, 1095

Meerson, 1987, Basic Res Cardiol, The role of lipid peroxidation in pathogenesis of arrhythmias and prevention of cardiac fibrillation with antioxidants, 123

Bernier, 1989, Am J Physiol, Reperfusion arrhythmias: Dose-related protection by anti-free radical interventions, H1344

Priori, 1990, Circulation, Early afterdepolarizations induced in vivo by reperfusion of ischemic myocardium.A possible mechanism for reperfusion arrhythmias, 1911

Kaplinsky, 1981, Circulation, Instantaneous and delayed ventricular arrhythmias after reperfusion of acutely ischemic myocardium: Evidence for multiple mechanisms, 333

Thomas, 2017, Contin Cardiol Educ, Ventricular arrhythmias in acute coronary syndromes – Mechanisms and management, 22

Piper, 1998, Cardiovasc Res, A fresh look at reperfusion injury, 291

Kloner, 1993, J Am Coll Cardiol, Does reperfusion injury exist in humans?, 537

Konstantinidis, 2012, Arterioscler Thromb Vasc Biol, Mechanisms of cell death in heart disease, 1552

Hotchkiss, 2009, N Engl J Med, Cell death, 1570

Eltzschig, 2011, Nat Med, Ischemia and reperfusion – from mechanism to translation, 1391

Vandenabeele, 2010, Nat Rev Mol Cell Biol, Molecular mechanisms of necroptosis: An ordered cellular explosion, 700

Zhang, 2016, Nat Med, CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis, 175

Tani, 1989, Circ Res, Role of intracellular Na+in Ca2+ overload and depressed recovery of ventricular function of reperfused ischemic rat hearts.Possible involvement of H+-Na+and Na+-Ca2+exchange, 1045

Lemasters, 1996, EXS, The pH paradox in ischemia-reperfusion injury to cardiac myocytes, 99

Kim, 2006, Am J Physiol Heart Circ Physiol, Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion, H2024

Steenbergen, 1987, Circ Res, Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart, 700

Jennings RB, Schaper J, Hill ML, Steenbergen C Jr., Reimer KA. Effect of reperfusion late in the phase of reversible ischemic injury. Changes in cell volume, electrolytes, metabolites, and ultrastructure. Circ Res 1985;56:262-78.

Garcia-Dorado, 2012, Cardiovasc Res, Calcium-mediated cell death during myocardial reperfusion, 168

Murphy, 2008, Physiol Rev, Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury, 581

Piper, 1989, Klin Wochenschr, Energy deficiency, calcium overload or oxidative stress: Possible causes of irreversible ischemic myocardial injury, 465

Halestrap, 2006, Biochem Soc Trans, Calcium, mitochondria and reperfusion injury: A pore way to die, 232

Kusuoka, 1987, J Clin Invest, Pathophysiology and pathogenesis of stunned myocardium.Depressed Ca2+ activation of contraction as a consequence of reperfusion-induced cellular calcium overload in ferret hearts, 950

Granger, 2015, Redox Biol, Reperfusion injury and reactive oxygen species: The evolution of a concept, 524

Becker, 2004, Cardiovasc Res, New concepts in reactive oxygen species and cardiovascular reperfusion physiology, 461

Tarasov, 2012, Cell Calcium, Regulation of ATP production by mitochondrial Ca(2+), 28

Jouaville, 1999, Proc Natl Acad Sci U S A, Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming, 13807

Brookes, 2004, Am J Physiol Cell Physiol, Calcium, AT, and ROS: A mitochondrial love-hate triangle, C817

Halestrap, 2009, J Bioenerg Biomembr, Mitochondria and reperfusion injury of the heart – A holey death but not beyond salvation, 113

Halestrap, 2004, Cardiovasc Res, Mitochondrial permeability transition pore opening during myocardial reperfusion – A target for cardioprotection, 372

Griffiths, 1995, Biochem J, Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion, 93

Kroemer, 2007, Physiol Rev, Mitochondrial membrane permeabilization in cell death, 99

Frangogiannis, 2014, Nat Rev Cardiol, The inflammatory response in myocardial injury, repair, and remodelling, 255

Boros, 2006, Am J Transplant, New cellular and molecular immune pathways in ischemia/reperfusion injury, 652

Chen, 2010, Nat Rev Immunol, Sterile inflammation: Sensing and reacting to damage, 826

Oyama, 2004, Circulation, , Liu X, Pu M, Kobzik L, Kelly RA, et al. Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice, 784

Timmers, 2012, Cardiovasc Res, The innate immune response in reperfused myocardium, 276

Linfert, 2009, Transplant Rev (Orlando), Lymphocytes and ischemia-reperfusion injury, 1

Armstrong, 2004, Cardiovasc Res, Protein kinase activation and myocardial ischemia/reperfusion injury, 427

Newton, 1995, J Biol Chem, Protein kinase C: Structure, function, and regulation, 28495

Gopalakrishna, 2000, Free Radic Biol Med, Protein kinase C signaling and oxidative stress, 1349

Inagaki, 2003, Circulation, Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo, 2304

Liu, 1994, Cardiovasc Drugs Ther, Chelerythrine, a highly selective protein kinase C inhibitor, blocks the anti-infarct effect of ischemic preconditioning in rabbit hearts, 881

Ytrehus, 1994, Am J Physiol, Preconditioning protects ischemic rabbit heart by protein kinase C activation, H1145

Ping, 1997, Circ Res, Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity, 404

Mitchell, 1995, Circ Res, Preconditioning of isolated rat heart is mediated by protein kinase C, 73

Ping, 2002, J Clin Invest, Formation of protein kinase C (epsilon)-lck signaling modules confers cardioprotection, 499

Saurin, 2002, Cardiovasc Res, Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts, 672

Inagaki, 2006, Cardiovasc Res, Epsilon protein kinase C as a potential therapeutic target for the ischemic heart, 222

Hausenloy, 2004, Cardiovasc Res, New directions for protecting the heart against ischaemia-reperfusion injury: Targeting the reperfusion injury salvage kinase (RISK)-pathway, 448

Hausenloy, 2005, Trends Cardiovasc Med, The reperfusion injury salvage kinase pathway: A common target for both ischemic preconditioning and postconditioning, 69

Hausenloy, 2007, Heart Fail Rev, Reperfusion injury salvage kinase signalling: Taking a RISK for cardioprotection, 217

Lecour, 2009, J Mol Cell Cardiol, Activation of the protective survivor activating factor enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?, 32

Omura, 2001, J Mol Cell Cardiol, Myocardial ischemia activates the JAK-STAT pathway through angiotensin II signaling in in vivo myocardium of rats, 307

Xuan, 2001, Proc Natl Acad Sci U S A, An essential role of the JAK-STAT pathway in ischemic preconditioning, 9050

Hadebe, 2018, Basic Res Cardiol, The SAFE pathway for cardioprotection: Is this a promising target?, 9

Lecour, 2005, Circulation, Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase), 3911

Kalakech, 2014, PLoS One, RISK and SAFE signaling pathway involvement in apolipoprotein A-I-induced cardioprotection, e107950

Kelly, 2010, Basic Res Cardiol, Ethanolamine is a novel STAT-3 dependent cardioprotective agent, 763

Hunter, 1995, Cell, Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling, 225

Takada, 2004, J Pharmacol Exp Ther, Cytoprotective effect of sodium orthovanadate on ischemia/reperfusion-induced injury in the rat heart involves akt activation and inhibition of fodrin breakdown and apoptosis, 1249

Ping, 1999, Circ Res, Demonstration of selective protein kinase C-dependent activation of Src and lck tyrosine kinases during ischemic preconditioning in conscious rabbits, 542

Takeishi, 1999, Circ Res, Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts, 1164

Takeishi, 2001, J Mol Cell Cardiol, Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: Modulation of MAP kinases activation by ischemic preconditioning, 1989

Aikawa, 1997, J Clin Invest, Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats, 1813

Yuan, 2010, Mol Cell Endocrinol, Activation of Src protein tyrosine kinase plays an essential role in urocortin-mediated cardioprotection, 1

Tonks, 2006, Nat Rev Mol Cell Biol, Protein tyrosine phosphatases: From genes, to function, to disease, 833

Liem, 2004, J Pharmacol Exp Ther, The tyrosine phosphatase inhibitor bis (maltolato) oxovanadium attenuates myocardial reperfusion injury by opening ATP-sensitive potassium channels, 1256

Bhuiyan, 2008, Cardiovasc Ther, Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein, 10

Besnier, 2014, FASEB J, Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B-deficient mice, 3351

Song, 2008, Apoptosis, Small interference RNA against PTP-1B reduces hypoxia/reoxygenation induced apoptosis of rat cardiomyocytes, 383

Hopkins, 2014, Trends Biochem Sci, PTEN function: The long and the short of it, 183

Hlobilková, 2003, Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, The mechanism of action of the tumour suppressor gene PTEN, 19

Cai, 2005, Circ Res, PTEN activity is modulated during ischemia and reperfusion: Involvement in the induction and decay of preconditioning, 1351