Clinical impact of MYC abnormalities in plasma cell myeloma

Cancer Genetics - Tập 228 - Trang 115-126 - 2018
Rolando García1, Weina Chen1, Prasad Koduru1
1Department of Pathology, UT Southwestern Medical, 5323 Harry Hines Blvd, Dallas, TX 75390, United States of America

Tài liệu tham khảo

Manier, 2017, Genomic complexity of multiple myeloma and its clinical implications, Nat Rev Clin Oncol, 14, 100, 10.1038/nrclinonc.2016.122 Morgan, 2012, The genetic architecture of multiple myeloma, Nat Rev Cancer, 12, 335, 10.1038/nrc3257 Walker, 2015, APOBEC family mutational signatures are associated with poor progresis in translocations in multiple myeloma, Nat Commun, 6, 6997, 10.1038/ncomms7997 Fonesca, 2003, The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma, Blood, 102, 2562, 10.1182/blood-2003-02-0493 Munshi, 2011, Consensus recommendations for risk stratification in multiple myeloma: report of the international myeloma workshop consensus panel 2, Blood, 117, 4696, 10.1182/blood-2010-10-300970 Chang, 2010, 1p21 deletions are strongly associated with 1q21 gains and are an independent adverse prognostic factor for the outcome of high-dose chemotherapy in pateints with multiple myeloma, Bone Marrow Transpl, 45, 117, 10.1038/bmt.2009.107 Glitza, 2015, Chromosome 8q24.1/c-MYC abnormality: a marker for high-risk myeloma, Leuk Lymphoma, 56, 602, 10.3109/10428194.2014.924116 Avet-Loiseau, 2001, Rearranements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors, Blood, 98, 3082, 10.1182/blood.V98.10.3082 Affer, 2014, Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma, Leukemia, 28, 1725, 10.1038/leu.2014.70 Walker, 2014, Translcoations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients, Blood Cancer J, 4, e191, 10.1038/bcj.2014.13 Chiecchio, 2009, Frequent upregulation of MYC in plasma cell leukemia, Genes Chromosomes Cancer, 48, 624, 10.1002/gcc.20670 Chang, 2011, Clinical and biological implication of MYC activation: a common diffeence between MGUS and newly diagnosed multiple myeloma, Leukemia, 25, 1026, 10.1038/leu.2011.53 Rahnenfuhrer, 2005, Estimating cancer survival and clnical outcome based on genetic tumor progression scores, Bioinformatics, 21, 2438, 10.1093/bioinformatics/bti312 Bogojeska, 2008, An R package for estimating evolutionary pathways and genetic proression scores, Bioinformatics, 24, 2391, 10.1093/bioinformatics/btn410 Ketter, 2007, Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas, Int J Cancer, 121, 1473, 10.1002/ijc.22855 Urbschat, 2011, Clonal cytogenetic proression within intratumorally heterogeneous meningiomas predicts tumor recurrence, Int J Oncol, 39, 1601 An International Sysem for Human Cytogenetic Nomenclature. Eds.McGowan-Joran J, Simons A, Schmid M, Karger, basel, 2016. Feinerer, 2008, Text mining infrastructure in R, Stat Softw, 25, 1 Ramazzotti, 2015, CAPRI: efficient inference of cancer progression models from cross-sectional data, Bioinformatics, 31, 3016, 10.1093/bioinformatics/btv296 De Sano, 2016, RANCO: an R package for the inference of cancer progression models from heterogeneous genomic data, Bioinformatics, 32, 1911, 10.1093/bioinformatics/btw035 Bolli, 2014, Heterogeneity of genomic evolution and mutational profiles in multiple myeloma, Nat Commun, 5, 2997, 10.1038/ncomms3997 Chung, 2007, Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling, Cancer Res, 67, 2982, 10.1158/0008-5472.CAN-06-4046 Pedersen, 2014, MYC translocaton partner gene determines survival of patients with large B-cell lymphoma with MYC- or double-hit MYC/BCL2 translocations, Eur J Haematol, 92, 42, 10.1111/ejh.12212