Clinical and molecular characteristics of patients with non-amyloid light chain deposition disorders, and outcome following treatment with high-dose melphalan and autologous stem cell transplantation

Bone Marrow Transplantation - Tập 38 Số 5 - Trang 339-343 - 2006
Karin I. Weichman1, Laura M. Dember2, Tatiana Prokaeva2, Daniel G. Wright1, Karen Quillen3, Michael Rosenzweig2, M Skinner2, David C. Seldin2, Vaishali Sanchorawala2
1Department of Medicine, Section of Hematology/Oncology, Boston University Medical Center, Boston, MA, USA
2Amyloid Treatment and Research Program, Boston University Medical Center, Boston, MA, USA
3Department of Laboratory Medicine, Boston University Medical Center, Boston, MA, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Randall RE, Williamson Jr WC, Mullinax F, Tung NY, Still WJ . Manifestations of systemic light chain deposition. Am J Med 1976; 60: 293–299.

Heilman RL, Velosa JA, Holley KE, Offord KP, Kyle RA . Long-term follow-up and response to chemotherapy in patients with light-chain deposition disease. Am J Kidney Dis 1992; 20: 34–41.

Royer B, Arnulf B, Martinez F, Roy L, Flaguel B, Etienne I et al. High dose chemotherapy in light chain or light and heavy chain deposition disease. Kidney Int 2004; 65: 642–648.

Firkin F, Hill PA, Dwyer K, Gock H . Reversal of dialysis-dependent renal failure in light-chain deposition disease by autologous peripheral blood stem cell transplantation. Am J Kidney Dis 2004; 44: 551–555.

Pozzi C, D'Amico M, Fogazzi GB, Curioni S, Ferrario F, Pasquali S et al. Light chain deposition disease with renal involvement: clinical characteristics and prognostic factors. Am J Kidney Dis 2003; 42: 1154–1163.

Terashima K, Takahashi K, Kojima M, Imai Y, Tsuchida S, Migita S et al. Kappa-type light chain crystal storage histiocytosis. Acta Pathol Jpn 1978; 28: 111–138.

Lebeau A, Zeindl-Eberhart E, Muller EC, Muller-Hocker J, Junbult PR, Emmerich B et al. Generalized crystal-storing histiocytosis associated with monoclonal gammopathy: molecular analysis of a disorder with rapid clinical course and review of the literature. Blood 2002; 100: 1817–1827.

Welschof M, Terness P, Kolbinger F, Zewe M, Dubel S, Dorsam H et al. Amino acid sequence based PCR primers for amplification of rearranged human heavy and light chain immunoglobulin variable region genes. J Immunol Methods 1995; 179: 203–214.

Lossos IS, Tibshirani R, Narasimhan B, Levy R . The inference of antigen selection on Ig genes. J Immunol 2000; 165: 5122–5126.

Lin J, Markowitz GS, Valeri AM, Kambham N, Sherman WH, Appel GB et al. Renal monoclonal immunoglobulin deposition disease: the disease spectrum. J Am Soc Nephrol 2001; 12: 1482–1492.

Sethi S, Cuiffo BP, Pinkus GS, Rennke HG . Crystal-storing histiocytosis involving the kidney in a low-grade B-cell lymphoproliferative disorder. Am J Kidney Dis 2002; 39: 183–188.

Foster SJ, Brezinschek HP, Brezinschek RI, Lipsky PE . Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells. J Clin Invest 1997; 99: 1614–1627.

Deret S, Chomilier J, Huang D, Preud'homme JL, Stevens FJ, Aucouturier P et al. Molecular modeling of immunoglobulin light chains implicates hydrophobic residues in non-amyloid light chain deposition disease. Protein Eng 1997; 10: 1191–1197.

Cogne M, Preud'homme JL, Bauwens M, Touchard G, Aucouturier P . Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease. J Clin Invest 1991; 87: 2186–2190.

Child JA, Morgan GJ, Davies FE, Owen RG, Bell SE, Hawkins K et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348: 1875–1883.

Attal M, Harousseau JL, Stoppa AM, Sotto JJ, Fuzibet JG, Rossi JF et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996; 335: 91–97.

Skinner M, Sanchorawala V, Seldin DC, Dember LM, Falk RH, Berk JL et al. High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med 2004; 140: 85–93.