Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

Clinical Infectious Diseases - Tập 52 Số 3 - Trang e18-e55 - 2011
Catherine Liu1, Arnold S. Bayer2,3, Sara E. Cosgrove4, Robert C. Solomon5, Scott K. Fridkin6, Rachel Gorwitz6, Sheldon L. Kaplan7, Adolf W. Karchmer8, Donald P. Levine9, Barbara E. Murray10, Michael J. Rybak11,9, David A. Talan2,12, Henry F. Chambers1,13
1Department of Medicine, Division of Infectious Diseases, University of California-San Francisco, San Francisco, California
2Department of Medicine, David Geffen School of Medicine at University of California- Los Angeles
3Division of Infectious Diseases, Harbor-UCLA Medical Center, Torrance, CA
4Division of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, Maryland
5Department of Pediatrics, Section of Infectious Diseases, University of Chicago, Chicago, Illinois
6Division of Healthcare Quality Promotion, Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
7Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas
8Division of Infectious Diseases, Beth Israel Deaconess Medicine Center, Harvard Medical School, Boston, Massachusetts
9Department of Medicine, Division of Infectious Diseases, Wayne State University, Detroit Receiving Hospital and University Health Center, Detroit, Michigan
10Division of Infectious Diseases and Center for the Study of Emerging and Re-emerging Pathogens, University of Texas Medical School, Houston, Texas
11Deparment of Pharmacy Practice, Wayne State University, Detroit Michigan
12Divisions of Emergency Medicine and Infectious Diseases, Olive View-UCLA Medical Center, Sylmar, CA
13Division of Infectious Diseases, San Francisco General Hospital, San Francisco, CA

Tóm tắt

AbstractEvidence-based guidelines for the management of patients with methicillin-resistant Staphylococcus aureus (MRSA) infections were prepared by an Expert Panel of the Infectious Diseases Society of America (IDSA). The guidelines are intended for use by health care providers who care for adult and pediatric patients with MRSA infections. The guidelines discuss the management of a variety of clinical syndromes associated with MRSA disease, including skin and soft tissue infections (SSTI), bacteremia and endocarditis, pneumonia, bone and joint infections, and central nervous system (CNS) infections. Recommendations are provided regarding vancomycin dosing and monitoring, management of infections due to MRSA strains with reduced susceptibility to vancomycin, and vancomycin treatment failures.

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